Antiarrhythmic effects of the highly selective late sodium channel current blocker GS-458967

Heart Rhythm

Volumn 10, Issue 7, 2013, Pages 1036-1043

  Sicouri, Serge ^a   Belardinelli, Luiz ^b   Antzelevitch, Charles ^a  

^a MASONIC MEDICAL RESEARCH LABORATORY   (United States)

^b GILEAD SCIENCES   (United States)

Author keywords

Antiarrhythmic drugs; Electrophysiology; Late sodium current; Pharmacology; Ranolazine

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; CALCIUM; GS 458967; ISOPRENALINE; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; ELECTROPHYSIOLOGY; EXPERIMENTAL DOG; HEART ARRHYTHMIA; MEMBRANE POTENTIAL; MEMBRANE STEADY POTENTIAL; MICROELECTRODE; NONHUMAN; PRIORITY JOURNAL; PULMONARY VEIN; PURKINJE FIBER; QT PROLONGATION; SUPERIOR CAVA VEIN;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; DISEASE MODELS, ANIMAL; DOGS; ELECTROPHYSIOLOGICAL PHENOMENA; HEART CONDUCTION SYSTEM; MEMBRANE POTENTIALS; PYRIDINES; SODIUM CHANNEL BLOCKERS; TRIAZOLES;

EID: 84879486271     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.03.023     Document Type: Article

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