Assisted reproductive technologies impair the expression and methylation of insulin-induced gene 1 and sterol regulatory element-binding factor 1 in the fetus and placenta

Fertility and Sterility

Volumn 101, Issue 4, 2014, Pages

  Lou, Hangying ^a,b   Le, Fang ^a   Zheng, Yingming ^a   Li, Lejun ^a   Wang, Liya ^a   Wang, Ning ^a   Zhu, Yimin ^a,b   Huang, Hefeng ^a,b   Jin, Fan ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Assisted reproductive technology (ART); fetus; insulin induced gene 1 (INSIG1); placenta; sterol regulatory element binding protein 1 (SREBP1)

Indexed keywords

APOLIPOPROTEIN B; GENOMIC DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL;

ADULT; ARTICLE; BIRTH WEIGHT; CESAREAN SECTION; CHOLESTEROL METABOLISM; CHORION VILLUS; CONGENITAL MALFORMATION; CONTROLLED STUDY; DISEASE DURATION; DNA METHYLATION; FEMALE; FETUS; FETUS DISEASE; GENETIC TRANSCRIPTION; GESTATIONAL AGE; GESTATIONAL SAC; GROWTH DISORDER; HUMAN; INFERTILITY THERAPY; INSULIN INDUCED GENE 1; INTRACYTOPLASMIC SPERM INJECTION; LIPID BLOOD LEVEL; LIVE BIRTH; MALE; MATERNAL AGE; MATERNAL BLOOD; MULTIPLE PREGNANCY; OUTCOME ASSESSMENT; OVARY HYPERSTIMULATION; PATERNAL AGE; PLACENTA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYROSEQUENCING; SEX RATIO; SIGNAL TRANSDUCTION; SUBFERTILITY; TEACHING HOSPITAL; UMBILICAL CORD BLOOD;

ASSISTED REPRODUCTIVE TECHNOLOGY (ART); FETUS; INSULIN-INDUCED GENE 1 (INSIG1); PLACENTA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1 (SREBP1);

ADULT; CHOLESTEROL; DNA METHYLATION; FEMALE; FETUS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; ORGAN SPECIFICITY; PLACENTA; PREGNANCY; REPRODUCTIVE TECHNIQUES, ASSISTED; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84897394924     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.12.034     Document Type: Article

References (38)

1. A. Nyboe Andersen, and K. Erb Register data on assisted reproductive technology (ART) in Europe including a detailed description of ART in Denmark Int J Androl 29 2006 12 16
2. L.A. Kondapalli, and A. Perales-Puchalt Low birth weight: is it related to assisted reproductive technology or underlying infertility? Fertil Steril 99 2013 303 310
3. A. Moini, M. Shiva, A. Arabipoor, R. Hosseini, M. Chehrazi, and M. Sadeghi Obestetic and neonatal outcomes of twin pregnancies conceived by assisted reproductive technology compared with twin pregnancies conceived spontaneously: a prospective follow-up study Eur J Obstet Gynecol Reprod Biol 165 2012 29 32
4. J.F. Kawwass, S. Crawford, D.M. Kissin, D.R. Session, S. Boulet, and D.J. Jamieson Tubal factor infertility and perinatal risk after assisted reproductive technology Obstet Gynecol 121 2013 1263 1271
5. K.T. Jenkins, L.S. Merkens, M.R. Tubb, L. Myatt, W.S. Davidson, and R.D. Steiner et al. Enhanced placental cholesterol efflux by fetal HDL in Smith-Lemli-Opitz syndrome Mol Genet Metab 94 2008 240 247
6. L.A. Woollett Maternal cholesterol in fetal development: transport of cholesterol from the maternal to the fetal circulation Am J Clin Nutr 82 2005 1155 1161
7. D.S. Lin, R.M. Pitkin, and W.E. Connor Placental transfer of cholesterol into the human fetus Am J Obstet Gynecol 128 1977 735 739
8. J.M. Dietschy, S.D. Turley, and D.K. Spady Role of liver in the maintenance of cholesterol and low-density lipoprotein homeostasis in different animal species, including humans J Lipid Res 34 1993 1637 1659
9. M.S. Brown, and J.L. Goldstein The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor Cell 89 1997 331 340
10. Y.A. Moon, G. Liang, X. Xie, M. Frank-Kamenetsky, K. Fitzgerald, and V. Koteliansky et al. The Scap/SREBP pathway in essential for developing diabetic fatty liver and carbonhydrate-induced hypertriglyceridemia in animals Cell Metab 15 2012 240 246
11. T. Yang, P.J. Espenshade, M.E. Wright, D. Yabe, Y. Gong, and R. Aebersold et al. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER Cell 110 2002 489 500
12. M.S. Brown, and J.L. Goldstein A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood Proc Natl Acad Sci 96 1999 11041 11048
13. J.D. Horton, J.L. Goldstein, and M.S. Brown SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver J Clin Invest 109 2002 1125 1131
14. A.C. Collier, S.J. Miyagi, Y. Yamauchi, and M.A. Ward Assisted reproduction technologies impair placental steroid metabolism J Steroid Biochem Mol Biol 116 2009 21 28
15. M. Ceelen, M.M. van Weissenbruch, J.C. Roos, J.P. Vermeiden, F.E. van Leeuwen, and H.A. Delemarre-Van de Waal Body composition in children and adolescents born after in vitro fertilization or spontaneous conception J Clin Endocrinol Metab 92 2007 3417 3423
16. M. Ceelen, M.M. van Weissenbruch, J.P. Vermeiden, F.E. van Leeuwen, and H.A. Delemarre-Van de Waal Cardiometabolic differences in children born after in vitro fertilization: follow-up study J Clin Endocrinol Metab 93 2008 1682 1688
17. M. Ceelen, M.M. van Weissenbruch, J.P. Vermeiden, F.E. van Leeuwen, and H.A. Delemarre-van de Waal Pubertal development in children and adolescents born after IVF and spontaneous conception Hum Reprod 23 2008 2791 2798
18. H.L. Miles, P.L. Hofman, J. Peek, M. Harris, D. Wilson, and E.M. Robinson et al. In vitro fertilization improves childhood growth and metabolism J Clin Endocrinol Metab 92 2007 3441 3445
19. S.D. Sokka, D. Loutradis, C. Kanaka-Gantenbein, A. Margeli, M. Papastamataki, and I. Papassotiriou et al. Absence of insulin resistance and low-grade inflammation despite early metabolic syndrome manifestations in children born after in vitro fertilization Fertil Steril 94 2010 1693 1699
20. A.J. Matkins, D. Platt, T. Papenbrock, A. Wilkins, J.J. Eckert, and W.Y. Kwong et al. Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure Proc Natl Acad Sci USA 104 2007 5449 5454
21. K. Takaishi, L. Duplomb, M.Y. Wang, J. Li, and R.H. Unger Hepatic insig-1 or-2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rat and in fasted/refed normal rats Proc Natl Acad Sci USA 101 2004 7106 7111
22. G. Mingrone, G. Rosa, A.V. Greco, M. Manco, N. Vega, and G. Nanni et al. Intramyocitic lipid accumulation and SREBP-1c expression are ralated to insulin resisance and cardiovascular risk in morbid obesity Atherosclerosis 170 2003 155 161
23. L.C. Li, and R. Dahiya MethPrimer: designing primers for methylation PCRs Bioinformatics 18 2002 1427 1431
24. F. Le, L.Y. Wang, N. Wang, L. Li, J. Li le, and Y.M. Zheng et al. In vitro fertilization alters growth and expression of Igf2/H19 and their epigenetic mechanisms in the liver and skeletal muscle of newborn and elder mice Biol Reprod 88 2013 1 10
25. N. Stefan, K. Kantartzis, and H.U. Häring Causes and metabolic consequences of fatty liver Endocrinol Rev 29 2008 939 960
26. B. Desvergne, L. Michalik, and W. Wahli Transcriptional regulation of metabolism Physiol Rev 86 2006 465 514
27. J. Li, X. Yu, W. Pan, and R.H. Unger Gene expression profile of rat adipose tissue at the onset of high-fat-diet obesity Am J Physiol Endocrinol Metab 282 2002 E1334 E1341
28. J. Li, K. Takaishi, W. Cook, S.K. McCorkle, and R.H. Unger Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes Proc Natl Acad Sci U S A 100 2003 9476 9481
29. E.M. Smith, Y. Zhang, T.M. Baye, S. Gawrieh, R. Cole, and J. Blangero et al. INSIG1 influences obesity-related hypertriglyceridemia in humans J Lipid Res 51 2010 701 708
30. L.E. Young, and H.R. Fairburn Improving the safety of embryo technologies: possible role of genomic imprinting Theriogenology 53 2000 627 648
31. S. Khosla, W. Dean, D. Brown, W. Reik, and R. Feil Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes Biol Reprod 64 2001 918 926
32. L.B. Romundstad, P.R. Romundstad, A. Sunde, V. von During, R. Skjaven, and D. Gunnell et al. Effects of technology or maternal factors on perinatal outcome after assisted fertilization: a population-based cohort study Lancet 372 2008 737 743
33. C.C. Boissonnas, H.E. Abdalaoui, V. Haelewyn, P. Fauque, J.M. Dupont, and I. Gut et al. Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men Eur J Hum Genet 18 2010 73 80
34. H. Kobayashi, H. Hiura, R.M. John, A. Sato, E. Otsu, and N. Kobayashi et al. DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm Eur J Hum Genet 17 2009 1582 1591
35. M.R. Mann, S.S. Lee, A.S. Doherty, R.I. Verona, L.D. Nolen, and R.M. Schultz et al. Selective loss of imprinting in the placenta following preimplantation development in culture Development 131 2004 3727 3735
36. J.H. Dean, M.G. Chapman, and E.A. Sullivan The effect on human sex ratio at birth by assisted reproductive technology (ART) procedures - an assessment of babies born following single embryo transfers, Australia and New Zealand, 2002-2006 Br J Obstet Gynaecol 117 2010 1628 1634
37. T. Chiang, R.M. Schultz, and M.A. Lampson Meiotic origins of maternal age-related aneuploidy Biol Reprod 86 2012 1 7
38. I. Shimomura, H. Shimano, J.D. Horton, J.L. Goldstein, and M.S. Brown Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells J Clin Invest 99 1997 838 845