Using matched molecular series as a predictive tool to optimize biological activity

Journal of Medicinal Chemistry

Volumn 57, Issue 6, 2014, Pages 2704-2713

  O'Boyle, Noel M ^a   Boström, Jonas ^b   Sayle, Roger A ^a   Gill, Adrian ^b  

^a NextMove Software Ltd   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALKANE; HALIDE; SUNITINIB;

ALGORITHM; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOLOGICAL ACTIVITY; DATA BASE; HYPOTHESIS; IC 50; METHODOLOGY; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; PREDICTOR VARIABLE;

ALGORITHMS; ALKANES; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DATABASES, CHEMICAL; DRUG DESIGN; MOLECULAR STRUCTURE; PREDICTIVE VALUE OF TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84897391807     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500022q     Document Type: Article

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