Complete Freund's adjuvant-induced acute inflammatory pain could be attenuated by triptolide via inhibiting spinal glia activation in rats

Journal of Surgical Research

Volumn 188, Issue 1, 2014, Pages 174-182

  Xu, Fei ^a   Li, Youhan ^a   Li, Shuo ^a   Ma, Yunqing ^b   Zhao, Ning ^c   Liu, Yong ^d   Qian, Niansong ^e   Zhao, Hong ^e   Li, Yu ^a  

^a BEIJING 302 HOSPITAL   (China)

^b 304TH HOSPITAL   (China)

^c AIR FORCE GENERAL HOSPITAL   (China)

^d NAVY GENERAL HOSPITAL   (China)

^e CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Glia; Inflammatory pain; pERK; Triptolide

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BIOLOGICAL MARKER; FREUND ADJUVANT; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OX42 PROTEIN; PROTEIN; TRIPTOLIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPERIMENTAL BEHAVIORAL TEST; GLIA; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; INFLAMMATORY PAIN; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL CORD; WESTERN BLOTTING;

GLIA; INFLAMMATORY PAIN; PERK; TRIPTOLIDE;

ACUTE PAIN; ANIMALS; CYTOKINES; DITERPENES; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; EPOXY COMPOUNDS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREUND'S ADJUVANT; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; NEUROGLIA; PHENANTHRENES; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84897381653     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.11.1087     Document Type: Article

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