Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK

Biochemical Pharmacology

Volumn 88, Issue 3, 2014, Pages 334-350

  Wang, Xue ^a   Wang, Xu Lei ^a,b   Chen, Hua Li ^a   Wu, Dan ^a   Chen, Jia Xiang ^a   Wang, Xiao Xiao ^a   Li, Ru Li ^a   He, Jin Han ^a   Mo, Li ^a   Cen, Xiaobo ^a   Wei, Yu Quan ^a   Jiang, Wei ^a  

^a SICHUAN UNIVERSITY   (China)

^b SOUTHWEST JIAOTONG UNIVERSITY   (China)

Author keywords

AMPK; Autophagy; Doxorubicin; Ghrelin; p38 MAPK

Indexed keywords

ADENYLATE KINASE; CATALASE; DOXORUBICIN; GHRELIN; JANUS KINASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CARDIOTOXICITY; CELL DEATH; CELL SIZE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART PERFORMANCE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMPK; AUTOPHAGY; DOXORUBICIN; GHRELIN; P38-MAPK;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; AUTOPHAGY; CELL LINE; CELL SIZE; CELL SURVIVAL; DOXORUBICIN; ENZYME ACTIVATION; GHRELIN; MALE; MICE; MICE, INBRED C57BL; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; TOR SERINE-THREONINE KINASES;

EID: 84897116012     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.01.040     Document Type: Article

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