Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury

American Journal of Pathology

Volumn 172, Issue 3, 2008, Pages 592-602

  Jiang, Wei ^a   Hall, Sean R ^a   Moos, Michael P W ^a   Cao, Richard Yang ^a   Ishii, Satoshi ^d   Ogunyankin, Kofo O ^b   Melo, Luis G ^a,b   Funk, Colin D ^a,c  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c QUEEN S UNIVERSITY   (Canada)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 CARBOXYPHENYLTHIO) 5 HYDROXY 7,9,11,14 ICOSATETRAENOIC ACID; ALBUMIN I 125; CYSTEINYLLEUKOTRIENE 2 RECEPTOR; EARLY GROWTH RESPONSE FACTOR 1; INTERCELLULAR ADHESION MOLECULE 1; LEUKOTRIENE RECEPTOR BLOCKING AGENT; PEPTIDOLEUKOTRIENE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; GENE EXPRESSION; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM;

EID: 40449090322     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.070834     Document Type: Article

References (53)

1. LM Buja Myocardial ischemia and reperfusion injury Cardiovasc Pathol 14 2005 170 175
2. AL Moens MJ Claeys JP Timmermans CJ Vrints Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process Int J Cardiol 100 2005 179 190
3. JL Park BR Lucchesi Mechanisms of myocardial reperfusion injury Ann Thorac Surg 68 1999 1905 1912
4. P Di Napoli AA Taccardi R De Caterina A Barsotti Pathophysiology of ischemia-reperfusion injury: experimental data Ital Heart J 3 Suppl 4 2002 24S 28S
5. AM Lefer PS Tsao DJ Lefer XL Ma Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia FASEB J 5 1991 2029 2034
6. CD Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 2001 1871 1875
7. CD Funk Leukotriene modifiers as potential therapeutics for cardiovascular disease Nat Rev Drug Disc 4 2005 664 672
8. Y Hui CD Funk Cysteinyl leukotriene receptors Biochem Pharmacol 64 2002 1549 1557
9. G Folco G Rossoni C Buccellati F Berti J Maclouf A Sala Leukotrienes in cardiovascular diseases Am J Respir Crit Care Med 161 2000 S112 S116
10. P Ciana M Fumagalli ML Trincavelli C Verderio P Rosa D Lecca S Ferrario C Parravicini V Capra P Gelosa U Guerrini S Belcredito M Cimino L Sironi E Tremoli GE Rovati C Martini MP Abbracchio The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor EMBO J 25 2006 4615 4627
11. CE Heise BF O'Dowd DJ Figueroa N Sawyer T Nguyen DS Im R Stocco JN Bellefeuille M Abramovitz R Cheng DL Williams Jr Z Zeng Q Liu L Ma MK Clements N Coulombe Y Liu CP Austin SR George GP O'Neill KM Metters KR Lynch JF Evans Characterization of the human cysteinyl leukotriene 2 receptor J Biol Chem 275 2000 30531 30536
12. J Takasaki M Kamohara M Matsumoto T Saito T Sugimoto T Ohishi H Ishii T Ota T Nishikawa Y Kawai Y Masuho T Isogai Y Suzuki S Sugano K Furuichi The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor Biochem Biophys Res Commun 274 2000 316 322
13. K Lötzer R Spanbroek M Hildner A Urbach R Heller E Bretschneider H Galczenski JF Evans AJ Habenicht Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis Arterioscler Thromb Vasc Biol 23 2003 e32 e36
14. M Kamohara J Takasaki M Matsumoto Si Matsumoto T Saito T Soga H Matsushime K Furuichi Functional characterization of cysteinyl leukotriene CysLT(2) receptor on human coronary artery smooth muscle cells Biochem Biophys Res Commun 287 2001 1088 1092
15. Y Hui G Yang H Galczenski DJ Figueroa CP Austin NG Copeland DJ Gilbert NA Jenkins CD Funk The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization J Biol Chem 276 2001 47489 47495
16. Y Hui Y Cheng I Smalera W Jian L Goldhahn GA Fitzgerald CD Funk Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure Circulation 110 2004 3360 3366
17. Y Kanaoka JA Boyce Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses J Immunol 173 2004 1503 1510
18. NG Frangogiannis CW Smith ML Entman The inflammatory response in myocardial infarction Cardiovasc Res 53 2002 31 47
19. S Barst K Mullane The release of a leukotriene D4-like substance following myocardial infarction in rabbits Eur J Pharmacol 114 1985 383 387
20. M Carry V Korley JT Willerson L Weigelt AW Ford-Hutchinson P Tagari Increased urinary leukotriene excretion in patients with cardiac ischemia. In vivo evidence for 5-lipoxygenase activation Circulation 85 1992 230 236
21. GL Yu EQ Wei SH Zhang HM Xu LS Chu WP Zhang Q Zhang Z Chen RH Mei MH Zhao Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice Pharmacology 73 2005 31 40
22. SH Fang Y Zhou LS Chu WP Zhang ML Wang GL Yu F Peng EQ Wei Spatio-temporal expression of cysteinyl leukotriene receptor-2 mRNA in rat brain after focal cerebral ischemia Neurosci Lett 412 2007 78 83
23. G Sener O Sehirli A Velioglu-Ogunc S Cetinel N Gedik M Caner A Sakarcan BC Yegen Montelukast protects against renal ischemia/reperfusion injury in rats Pharmacol Res 54 2006 65 71
24. XS Chen JR Sheller EN Johnson CD Funk Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene Nature 372 1994 179 182
25. O Tarnavski JR McMullen M Schinke Q Nie S Kong S Izumo Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies Physiol Genom 16 2004 349 360
26. X Liu J Wei DH Peng MD Layne SF Yet Absence of heme oxygenase-1 exacerbates myocardial ischemia/reperfusion injury in diabetic mice Diabetes 54 2005 778 784
27. P Petzelbauer PA Zacharowski Y Miyazaki P Friedl G Wickenhauser FJ Castellino M Groger K Wolff K Zacharowski The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia-reperfusion injury Nat Med 11 2005 298 304
28. J Schumacher K Binkowski A Dendorfer KF Klotz Organ-specific extravasation of albumin-bound Evans blue during nonresuscitated hemorrhagic shock in rats Shock 20 2003 565 568
29. JG Younger N Sasaki J Delgado AC Ko TX Nghiem MD Waite GO Till PA Ward Systemic and lung physiological changes in rats after intravascular activation of complement J Appl Physiol 90 2001 2289 2295
30. E Harja LG Bucciarelli Y Lu DM Stern YS Zou AM Schmidt SF Yan Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation Circ Res 94 2004 333 339
31. T Takahashi T Tang NC Lai DM Roth B Rebolledo M Saito WY Lew P Clopton HK Hammond Increased cardiac adenylyl cyclase expression is associated with increased survival after myocardial infarction Circulation 114 2006 388 396
32. O Dewald G Ren GD Duerr M Zoerlein C Klemm C Gersch S Tincey LH Michael ML Entman NG Frangogiannis Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction Am J Pathol 164 2004 665 677
33. Y Okada G Scott MK Ray Y Mishina Y Zhang Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis Nature 450 2007 119 123
34. X Liu JA Simpson KR Brunt CA Ward SR Hall RT Kinobe V Barrette MY Tse SC Pang AS Pachori VJ Dzau K Ogunyankin LG Melo Pre-emptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function one year after acute myocardial infarction Am J Physiol 293 2007 H48 H59
35. SR Hall L Wang B Milne M Hong Left ventricular dysfunction after acute intracranial hypertension is associated with increased hydroxyl free radical production, cardiac ryanodine hyperphosphorylation, and troponin I degradation J Heart Lung Transplant 24 2005 1639 1649
36. P Anversa C Beghi Y Kikkawa G Olivetti Myocardial infarction in rats. Infarct size, myocyte hypertrophy and capillary growth Circ Res 58 1986 26 37
37. T De Celle JP Cleutjens WM Balnkesteijn JJ Debets JF Smits BJ Janssen Long-term structural and functional consequences of cardiac ischemia-reperfusion injury in vivo in mice Exp Physiol 89 2004 605 615
38. GM Rubanyi The role of endothelium in cardiovascular homeostasis and disease J Cardiovasc Pharmacol 22 1993 S1 S4
39. K Sasaki A Ueno M Kswamura M Katori S Shigehiro R Kikawada Reduction of myocardial infarct size in rats by selective 5-lipooxygenase inhibitor (AA-861) Adv Prostglandin Thromboxane Leukot Res 17A 1987 381 383
40. G Rossoni A Sala F Berti T Testa C Buccellati C Molta R Muller-Peddinghaus J Maclouf GC Folco Myocardial protection by the leukotriene synthesis inhibitor BAY X1005: importance of transcellular biosynthesis of cysteinyl-leukotrienes J Pharmacol Exp Ther 276 1996 335 341
41. CE Hock LD Beck LA Papa Peptide leukotriene antagonism in myocardial ischemia and reperfusion Cardiovasc Res 26 1992 1206 1211
42. A Helgadottir A Manolescu G Thorleifsson S Gretarsdottir H Jonsdottir U Thorsteinsdottir NJ Samani G Gudmundsson SF Grant G Thorgeirsson S Sveinbjornsdottir EM Valdimarsson SE Matthiasson H Johannsson O Gudmundsdottir ME Gurney J Sainz M Thorhallsdottir M Andresdottir ML Frigge EJ Topol A Kong V Gudnason H Hakonarson JR Gulcher K Stefansson The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke Nat Genet 36 2004 233 239
43. A Sala G Folco Neutrophils, endothelial cells, and cysteinyl leukotrienes: a new approach to neutrophil-dependent inflammation? Biochem Biophys Res Commun 283 2001 1003 1006
44. KE Pedersen BS Bochner BJ Undem Cysteinyl leukotrienes induce P-selectin expression in human endothelial cells via a non-CysLT1 receptor-mediated mechanism J Pharmacol Exp Ther 281 1997 655 662
45. A Di Gennaro C Carnini C Buccellati R Ballerio S Zarini F Fumagalli S Viappiani L Librizzi A Hernandez RC Murphy G Constantin M De Curtis G Folco A Sala Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes FASEB J 18 2004 842 844
46. B Uzonyi K Lotzer S Jahn C Kramer M Hildner E Bretschneider D Radke M Beer R Vollandt JF Evans CD Funk AJ Habenicht Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells Proc Natl Acad Sci USA 103 2006 6326 6331
47. SF Yan T Fujita J Lu K Okada Y Shan Zou N Mackman DJ Pinsky DM Stern Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress. (Erratum in: Nat Med 2001, 7:509) Nat Med 6 2000 1355 1361
48. DJ Figueroa RM Breyer SK Defoe S Kargman BL Daugherty K Waldburger Q Liu M Clements Z Zeng GP O'Neill TR Jones KR Lynch CP Austin JF Evans Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes Am J Respir Crit Care Med 163 2001 226 233
49. A Adamek S Jung C Dienesch M Laser G Ertl J Bauersachs S Frantz Role of 5-lipoxygenase in myocardial ischemia-reperfusion injury in mice Eur J Pharmacol 57 2007 51 54
50. H Hu G Chen JM Zhang WP Zhang L Zhang QF Ge HT Yao W Ding Z Chen EQ Wei Distribution of cysteinyl leukotriene receptor 2 in human traumatic brain injury and brain tumors Acta Pharmacol Sin 26 2005 685 690
51. MT Crow K Mani Y-J Nam RN Kitsis The mitochondrial death pathway and cardiac myocyte apoptosis Circ Res 95 2004 957 970
52. F Eefting B Rensing J Wigman WJ Pannekoek WM Liu MJ Cramer DJ Lips PA Doevendans Role of apoptosis in reperfusion injury Cardiovasc Res 61 2004 414 426
53. C Duilio G Ambrosio P Kuppusamy A DiPaula LC Becker JL Zweier Neutrophils are primary source of O2 radicals during reperfusion after prolonged myocardial ischemia Am J Physiol 280 2001 H2649 H2657