Complex RNA folding kinetics revealed by single-molecule FRET and hidden Markov models

Journal of the American Chemical Society

Volumn 136, Issue 12, 2014, Pages 4534-4543

  Keller, Bettina G ^a   Kobitski, Andrei ^b   Jäschke, Andres ^c   Nienhaus, G Ulrich ^b,d   Noé, Frank ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d University of Illinois at Urbana Champaign   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINETIC ENERGY; MOLECULES;

ANALYSIS TECHNIQUES; COMPACT STRUCTURES; FOLDING KINETICS; FOLDING PATHWAY; SECONDARY STRUCTURES; SINGLE-MOLECULE FRETS; TERTIARY STRUCTURES; WATSON-CRICK BASE PAIRING;

HIDDEN MARKOV MODELS;

MAGNESIUM ION; RIBOZYME; RNA;

ARTICLE; BASE PAIRING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIDDEN MARKOV MODEL; HISTOGRAM; KINETICS; PHOTON; PHOTON BASED SINGLE MOLECULE FLUORESCENCE RESONANCE ENERGY TRANSFER; PROCESS OPTIMIZATION; PROTEIN SECONDARY STRUCTURE; RNA FOLDING; STRUCTURE ANALYSIS; TERTIARY WATSON CRICK BASE PAIRING; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; NUCLEOTIDE SEQUENCE; PROBABILITY;

BASE SEQUENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; MARKOV CHAINS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RNA FOLDING; RNA, CATALYTIC;

EID: 84897091038     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4098719     Document Type: Article

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