Metal-induced folding of diels-alderase ribozymes studied by static and time-resolved NMR spectroscopy

Journal of the American Chemical Society

Volumn 131, Issue 17, 2009, Pages 6261-6270

  Manoharan, Vijayalaxmi ^a   Fürtig, Boris ^a,c   Jäschke, Andres ^b   Schwalbe, Harald ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c MAX F PERUTZ LABORATORIES   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL HETEROGENEITY; DIELS-ALDER; DIELS-ALDERASE; FOLDING RATES; IN-SITU; LOCAL DYNAMICS; MIXING TECHNIQUES; MODEL-BASED; NMR SPECTROSCOPY; ORDERS OF MAGNITUDE; PSEUDOKNOT; RIBOZYMES; SINGLE NUCLEOTIDES; TIME-RESOLVED;

METAL IONS; MULTIUSER DETECTION; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACIDS; RNA; TRACE ANALYSIS;

METALS;

CALCIUM ION; LIGAND; METAL ION; RIBOZYME; RNA; CALCIUM; DIELS ALDER RIBOZYME; DIELS-ALDER RIBOZYME; METAL;

ARTICLE; CATALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC HETEROGENEITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FOLDING; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; BIOCATALYSIS; CHEMISTRY; CONFORMATION; DRUG EFFECT; METABOLISM; THERMODYNAMICS; TIME; X RAY CRYSTALLOGRAPHY;

BIOCATALYSIS; CALCIUM; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; METALS; NUCLEIC ACID CONFORMATION; RNA, CATALYTIC; THERMODYNAMICS; TIME FACTORS;

EID: 70149105259     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja900244x     Document Type: Article

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