Activation of innate immunity is required for efficient nuclear reprogramming

Cell

Volumn 151, Issue 3, 2012, Pages 547-558

  Lee, Jieun ^a   Sayed, Nazish ^a   Hunter, Arwen ^a   Au, Kin Fai ^a   Wong, Wing H ^a   Mocarski, Edward S ^c   Pera, Renee Reijo ^b   Yakubov, Eduard ^a   Cooke, John P ^a  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84868007347     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.09.034     Document Type: Article

References (44)

1. O. Adachi, T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function Immunity 9 1998 143 150
2. K. Agger, P.A. Cloos, J. Christensen, D. Pasini, S. Rose, J. Rappsilber, I. Issaeva, E. Canaani, A.E. Salcini, and K. Helin UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development Nature 449 2007 731 734
3. S. Akira, and K. Takeda Toll-like receptor signalling Nat. Rev. Immunol. 4 2004 499 511
4. L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 2001 732 738
5. A.J. Bannister, P. Zegerman, J.F. Partridge, E.A. Miska, J.O. Thomas, R.C. Allshire, and T. Kouzarides Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain Nature 410 2001 120 124
6. B. Beutler Inferences, questions and possibilities in Toll-like receptor signalling Nature 430 2004 257 263
7. L.A. Boyer, D. Mathur, and R. Jaenisch Molecular control of pluripotency Curr. Opin. Genet. Dev. 16 2006 455 462
8. T. Brambrink, R. Foreman, G.G. Welstead, C.J. Lengner, M. Wernig, H. Suh, and R. Jaenisch Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells Cell Stem Cell 2 2008 151 159
9. H.J. Cho, C.S. Lee, Y.W. Kwon, J.S. Paek, S.H. Lee, J. Hur, E.J. Lee, T.Y. Roh, I.S. Chu, and S.H. Leem Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation Blood 116 2010 386 395
10. J. Choe, M.S. Kelker, and I.A. Wilson Crystal structure of human toll-like receptor 3 (TLR3) ectodomain Science 309 2005 581 585
11. F. De Santa, M.G. Totaro, E. Prosperini, S. Notarbartolo, G. Testa, and G. Natoli The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing Cell 130 2007 1083 1094
12. M. Farlik, B. Reutterer, C. Schindler, F. Greten, C. Vogl, M. Müller, and T. Decker Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression Immunity 33 2010 25 34
13. K. Hagino-Yamagishi, L.A. Donehower, and H.E. Varmus Retroviral DNA integrated during infection by an integration-deficient mutant of murine leukemia virus is oligomeric J. Virol. 61 1987 1964 1971
14. M.S. Hayden, and S. Ghosh Signaling to NF-kappaB Genes Dev. 18 2004 2195 2224
15. M.S. Hayden, A.P. West, and S. Ghosh NF-kappaB and the immune response Oncogene 25 2006 6758 6780
16. T. Kaisho, and S. Akira Toll-like receptor function and signaling J. Allergy Clin. Immunol. 117 2006 979 987 quiz 988
17. H. Kato, S. Sato, M. Yoneyama, M. Yamamoto, S. Uematsu, K. Matsui, T. Tsujimura, K. Takeda, T. Fujita, O. Takeuchi, and S. Akira Cell type-specific involvement of RIG-I in antiviral response Immunity 23 2005 19 28
18. T. Kawai, and S. Akira The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors Nat. Immunol. 11 2010 373 384
19. D. Kim, C.H. Kim, J.I. Moon, Y.G. Chung, M.Y. Chang, B.S. Han, S. Ko, E. Yang, K.Y. Cha, R. Lanza, and K.S. Kim Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins Cell Stem Cell 4 2009 472 476
20. M. Lachner, D. O'Carroll, S. Rea, K. Mechtler, and T. Jenuwein Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins Nature 410 2001 116 120
21. Q. Li, and I.M. Verma NF-kappaB regulation in the immune system Nat. Rev. Immunol. 2 2002 725 734
22. G. Li, R. Margueron, M. Ku, P. Chambon, B.E. Bernstein, and D. Reinberg Jarid2 and PRC2, partners in regulating gene expression Genes Dev. 24 2010 368 380
23. D.A. Lim, Y.C. Huang, T. Swigut, A.L. Mirick, J.M. Garcia-Verdugo, J. Wysocka, P. Ernst, and A. Alvarez-Buylla Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells Nature 458 2009 529 533
24. N. Maherali, R. Sridharan, W. Xie, J. Utikal, S. Eminli, K. Arnold, M. Stadtfeld, R. Yachechko, J. Tchieu, and R. Jaenisch Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution Cell Stem Cell 1 2007 55 70
25. S.M. McWhirter, K.A. Fitzgerald, J. Rosains, D.C. Rowe, D.T. Golenbock, and T. Maniatis IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts Proc. Natl. Acad. Sci. USA 101 2004 233 238
26. H. Niwa How is pluripotency determined and maintained? Development 134 2007 635 646
27. H. Niwa Open conformation chromatin and pluripotency Genes Dev. 21 2007 2671 2676
28. K. Okita, T. Ichisaka, and S. Yamanaka Generation of germline-competent induced pluripotent stem cells Nature 448 2007 313 317
29. T.T. Onder, N. Kara, A. Cherry, A.U. Sinha, N. Zhu, K.M. Bernt, P. Cahan, B.O. Marcarci, J. Unternaehrer, and P.B. Gupta Chromatin-modifying enzymes as modulators of reprogramming Nature 483 2012 598 602
30. J.C. Peng, A. Valouev, T. Swigut, J. Zhang, Y. Zhao, A. Sidow, and J. Wysocka Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells Cell 139 2009 1290 1302
31. C.R. Roy, and E.S. Mocarski Pathogen subversion of cell-intrinsic innate immunity Nat. Immunol. 8 2007 1179 1187
32. A.A. Sharov, S. Masui, L.V. Sharova, Y. Piao, K. Aiba, R. Matoba, L. Xin, H. Niwa, and M.S. Ko Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data BMC Genomics 9 2008 269
33. M. Stadtfeld, and K. Hochedlinger Induced pluripotency: history, mechanisms, and applications Genes Dev. 24 2010 2239 2263
34. M. Stadtfeld, N. Maherali, D.T. Breault, and K. Hochedlinger Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse Cell Stem Cell 2 2008 230 240
35. K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
36. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872
37. K.V. Tarasov, Y.S. Tarasova, W.L. Tam, D.R. Riordon, S.T. Elliott, G. Kania, J. Li, S. Yamanaka, D.G. Crider, and G. Testa B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells PLoS ONE 3 2008 e2478
38. M. Wernig, A. Meissner, R. Foreman, T. Brambrink, M. Ku, K. Hochedlinger, B.E. Bernstein, and R. Jaenisch In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state Nature 448 2007 318 324
39. M. Wernig, C.J. Lengner, J. Hanna, M.A. Lodato, E. Steine, R. Foreman, J. Staerk, S. Markoulaki, and R. Jaenisch A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types Nat. Biotechnol. 26 2008 916 924
40. D. Wolf, and S.P. Goff TRIM28 mediates primer binding site-targeted silencing of murine leukemia virus in embryonic cells Cell 131 2007 46 57
41. E. Yakubov, G. Rechavi, S. Rozenblatt, and D. Givol Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors Biochem. Biophys. Res. Commun. 394 2010 189 193
42. M. Yamamoto, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway Science 301 2003 640 643
43. W.C. Yang, K.G. Patel, J. Lee, Y.T. Ghebremariam, H.E. Wong, J.P. Cooke, and J.R. Swartz Cell-free production of transducible transcription factors for nuclear reprogramming Biotechnol. Bioeng. 104 2009 1047 1058
44. H. Zhou, S. Wu, J.Y. Joo, S. Zhu, D.W. Han, T. Lin, S. Trauger, G. Bien, S. Yao, and Y. Zhu Generation of induced pluripotent stem cells using recombinant proteins Cell Stem Cell 4 2009 381 384