GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition

Osteoarthritis and Cartilage

Volumn 22, Issue 4, 2014, Pages 566-577

  Enochson, L ^a   Stenberg, J ^a   Brittberg, M ^b   Lindahl, A ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Canonical Wnt signaling; Chondrocytes; Growth and differentiation factor 5; Matrix metalloprotease 13; Osteoarthritis

Indexed keywords

AGGRECANASE 1; BETA CATENIN; COLLAGENASE 3; DICKKOPF 1 PROTEIN; GROWTH DIFFERENTIATION FACTOR 5; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSCRIPTION FACTOR SOX9; ACAN PROTEIN, HUMAN; ADAM PROTEIN; ADAMTS5 PROTEIN, HUMAN; AGGRECAN; COLLAGEN TYPE 12; DKK1 PROTEIN, HUMAN; FRZB PROTEIN; GLYCOPROTEIN; SIGNAL PEPTIDE; SOX9 PROTEIN, HUMAN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTICLE; CARTILAGE CELL; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL EXPANSION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WNT SIGNALING PATHWAY; ADULT; ARTICULAR CARTILAGE; METABOLISM; OSTEOARTHRITIS; PHYSIOLOGY;

ADAM PROTEINS; ADULT; AGGRECANS; BETA CATENIN; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGEN TYPE XII; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOPROTEINS; GROWTH DIFFERENTIATION FACTOR 5; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASE 13; OSTEOARTHRITIS; POLYMERASE CHAIN REACTION; SOX9 TRANSCRIPTION FACTOR; TISSUE INHIBITOR OF METALLOPROTEINASES; WNT SIGNALING PATHWAY;

EID: 84897026966     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2014.02.004     Document Type: Article

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