-
2
-
-
34047103363
-
A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis
-
Miyamoto, Y., Mabuchi, A., Shi, D., Kubo, T., Takatori, Y., Saito, S., Fujioka, M., Sudo, A., Uchida, A., Yamamoto, S. et al. (2007) A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat. Genet., 39, 529-533.
-
(2007)
Nat. Genet.
, vol.39
, pp. 529-533
-
-
Miyamoto, Y.1
Mabuchi, A.2
Shi, D.3
Kubo, T.4
Takatori, Y.5
Saito, S.6
Fujioka, M.7
Sudo, A.8
Uchida, A.9
Yamamoto, S.10
-
3
-
-
43049122786
-
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility
-
Chapman, K., Takahashi, A., Meulenbelt, I., Watson, C., Rodriguez-Lopez, J., Egli, R., Tsezou, A., Malizos, K.N., Kloppenburg, M., Shi, D. et al. (2008) A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Hum. Mol. Genet., 17, 1497-1504.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1497-1504
-
-
Chapman, K.1
Takahashi, A.2
Meulenbelt, I.3
Watson, C.4
Rodriguez-Lopez, J.5
Egli, R.6
Tsezou, A.7
Malizos, K.N.8
Kloppenburg, M.9
Shi, D.10
-
4
-
-
66449089103
-
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
-
Evangelou, E., Chapman, K., Meulenbelt, I., Karassa, F.B., Loughlin, J., Carr, A., Doherty, M., Doherty, S., Gomez-Reino, J.J., Gonzalez, A. et al. (2009) Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum., 60, 1710-1721.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1710-1721
-
-
Evangelou, E.1
Chapman, K.2
Meulenbelt, I.3
Karassa, F.B.4
Loughlin, J.5
Carr, A.6
Doherty, M.7
Doherty, S.8
Gomez-Reino, J.J.9
Gonzalez, A.10
-
5
-
-
78650964172
-
Association of genetic and mechanical factors with age of onset of knee osteoarthritis
-
Ji, J., Dai, J., Shi, D. and Jiang, Q. (2010) Association of genetic and mechanical factors with age of onset of knee osteoarthritis. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 27, 672-674.
-
(2010)
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
, vol.27
, pp. 672-674
-
-
Ji, J.1
Dai, J.2
Shi, D.3
Jiang, Q.4
-
6
-
-
34548409926
-
An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage
-
Southam, L., Rodriguez-Lopez, J., Wilkins, J.M., Pombo-Suarez, M., Snelling, S., Gomez-Reino, J.J., Chapman, K., Gonzalez, A. and Loughlin, J. (2007) An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage. Hum. Mol. Genet., 16, 2226-2232.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 2226-2232
-
-
Southam, L.1
Rodriguez-Lopez, J.2
Wilkins, J.M.3
Pombo-Suarez, M.4
Snelling, S.5
Gomez-Reino, J.J.6
Chapman, K.7
Gonzalez, A.8
Loughlin, J.9
-
7
-
-
70449729925
-
Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study
-
Vaes, R.B., Rivadeneira, F., Kerkhof, J.M., Hofman, A., Pols, H.A., Uitterlinden, A.G. and van Meurs, J.B. (2009) Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study. Ann. Rheum. Dis., 68, 1754-1760.
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1754-1760
-
-
Vaes, R.B.1
Rivadeneira, F.2
Kerkhof, J.M.3
Hofman, A.4
Pols, H.A.5
Uitterlinden, A.G.6
van Meurs, J.B.7
-
8
-
-
78650988509
-
The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance
-
Valdes, A.M., Evangelou, E., Kerkhof, H.J., Tamm, A., Doherty, S.A., Kisand, K., Kerna, I., Uitterlinden, A., Hofman, A., Rivadeneira, F. et al. (2011) The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance. Ann. Rheum. Dis., 70, 873-875.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 873-875
-
-
Valdes, A.M.1
Evangelou, E.2
Kerkhof, H.J.3
Tamm, A.4
Doherty, S.A.5
Kisand, K.6
Kerna, I.7
Uitterlinden, A.8
Hofman, A.9
Rivadeneira, F.10
-
9
-
-
77956361934
-
Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes
-
Valdes, A.M., McWilliams, D., Arden, N.K., Doherty, S.A., Wheeler, M., Muir, K.R., Zhang, W., Cooper, C., Maciewicz, R.A. and Doherty, M. (2010) Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. Arthritis Rheum., 62, 2688-2695.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2688-2695
-
-
Valdes, A.M.1
McWilliams, D.2
Arden, N.K.3
Doherty, S.A.4
Wheeler, M.5
Muir, K.R.6
Zhang, W.7
Cooper, C.8
Maciewicz, R.A.9
Doherty, M.10
-
10
-
-
0031464970
-
Cartilage-derived morphogenetic protein-1
-
Luyten, F.P. (1997) Cartilage-derived morphogenetic protein-1. Int. J. Biochem. Cell Biol., 29, 1241-1244.
-
(1997)
Int. J. Biochem. Cell Biol.
, vol.29
, pp. 1241-1244
-
-
Luyten, F.P.1
-
11
-
-
0010546206
-
Growth/Differentiation Factor-5 (GDF-5) and Skeletal Development
-
Buxton, P., Edwards, C., Archer, C.W. and Francis-West, P. (2001) Growth/Differentiation Factor-5 (GDF-5) and Skeletal Development. J. Bone. Joint. Surg. Am., 83, S23-S30.
-
(2001)
J. Bone. Joint. Surg. Am.
, vol.83
-
-
Buxton, P.1
Edwards, C.2
Archer, C.W.3
Francis-West, P.4
-
12
-
-
0032905901
-
Mechanisms of GDF-5 action during skeletal development
-
Francis-West, P.H., Abdelfattah, A., Chen, P., Allen, C., Parish, J., Ladher, R., Allen, S., MacPherson, S., Luyten, F.P. and Archer, C.W. (1999) Mechanisms of GDF-5 action during skeletal development. Development, 126, 1305-1315.
-
(1999)
Development
, vol.126
, pp. 1305-1315
-
-
Francis-West, P.H.1
Abdelfattah, A.2
Chen, P.3
Allen, C.4
Parish, J.5
Ladher, R.6
Allen, S.7
MacPherson, S.8
Luyten, F.P.9
Archer, C.W.10
-
13
-
-
0033178337
-
p38 Mitogen-Activated Protein Kinase Functionally Contributes to Chondrogenesis Induced by Growth/Differentiation Factor-5 in ATDC5 Cells
-
Nakamura, K., Shirai, T., Morishita, S., Uchida, S., Saeki-Miura, K. and Makishima, F. (1999) p38 Mitogen-Activated Protein Kinase Functionally Contributes to Chondrogenesis Induced by Growth/Differentiation Factor-5 in ATDC5 Cells. Exp. Cell Res., 250, 351-363.
-
(1999)
Exp. Cell Res.
, vol.250
, pp. 351-363
-
-
Nakamura, K.1
Shirai, T.2
Morishita, S.3
Uchida, S.4
Saeki-Miura, K.5
Makishima, F.6
-
14
-
-
0037330644
-
Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes
-
Settle, J.S.H., Rountree, R.B., Sinha, A., Thacker, A., Higgins, K. and Kingsley, D.M. (2003) Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev. Biol., 254, 116-130.
-
(2003)
Dev. Biol.
, vol.254
, pp. 116-130
-
-
Settle, J.S.H.1
Rountree, R.B.2
Sinha, A.3
Thacker, A.4
Higgins, K.5
Kingsley, D.M.6
-
15
-
-
0029936784
-
A human chondrodysplasia due to a mutation in a TGF-beta superfamily member
-
Thomas, J.T., Lin, K., Nandedkar, M., Camargo, M., Cervenka, J. and Luyten, F.P. (1996) A human chondrodysplasia due to a mutation in a TGF-beta superfamily member. Nat. Genet., 12, 315-317.
-
(1996)
Nat. Genet.
, vol.12
, pp. 315-317
-
-
Thomas, J.T.1
Lin, K.2
Nandedkar, M.3
Camargo, M.4
Cervenka, J.5
Luyten, F.P.6
-
16
-
-
0030763771
-
Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1
-
Thomas, J.T., Kilpatrick, M.W., Lin, K., Erlacher, L., Lembessis, P., Costa, T., Tsipouras, P. and Luyten, F.P. (1997) Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1. Nat. Genet., 17, 58-64.
-
(1997)
Nat. Genet.
, vol.17
, pp. 58-64
-
-
Thomas, J.T.1
Kilpatrick, M.W.2
Lin, K.3
Erlacher, L.4
Lembessis, P.5
Costa, T.6
Tsipouras, P.7
Luyten, F.P.8
-
17
-
-
24644515898
-
Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2
-
Seemann, P., Schwappacher, R., Kjaer, K.W., Krakow, D., Lehmann, K., Dawson, K., Stricker, S., Pohl, J., Ploger, F., Staub, E. et al. (2005) Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2. J. Clin. Invest., 115, 2373-2381.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2373-2381
-
-
Seemann, P.1
Schwappacher, R.2
Kjaer, K.W.3
Krakow, D.4
Lehmann, K.5
Dawson, K.6
Stricker, S.7
Pohl, J.8
Ploger, F.9
Staub, E.10
-
18
-
-
0031230465
-
Mutations in CDMP1 cause autosomal dominant brachydactyly type C
-
Polinkovsky, A., Robin, N.H., Thomas, J.T., Irons, M., Lynn, A., Goodman, F.R., Reardon, W., Kant, S.G., Brunner, H.G., van der Burgt, I. et al. (1997) Mutations in CDMP1 cause autosomal dominant brachydactyly type C. Nat. Genet., 17, 18-19.
-
(1997)
Nat. Genet.
, vol.17
, pp. 18-19
-
-
Polinkovsky, A.1
Robin, N.H.2
Thomas, J.T.3
Irons, M.4
Lynn, A.5
Goodman, F.R.6
Reardon, W.7
Kant, S.G.8
Brunner, H.G.9
van der Burgt, I.10
-
19
-
-
0037157775
-
Frameshift mutation in the cartilage-derived morphogenetic protein 1 (CDMP1) gene and severe acromesomelic chondrodysplasia resembling Grebe-type chondrodysplasia
-
Faiyaz-Ul-Haque, M., Ahmad, W., Wahab, A., Haque, S., Azim, A.C., Zaidi, S.H.E., Teebi, A.S., Ahmad, M., Cohn, D.H., Siddique, T. et al. (2002) Frameshift mutation in the cartilage-derived morphogenetic protein 1 (CDMP1) gene and severe acromesomelic chondrodysplasia resembling Grebe-type chondrodysplasia. Am. J. Med. Genet., 111, 31-37.
-
(2002)
Am. J. Med. Genet.
, vol.111
, pp. 31-37
-
-
Faiyaz-Ul-Haque, M.1
Ahmad, W.2
Wahab, A.3
Haque, S.4
Azim, A.C.5
Zaidi, S.H.E.6
Teebi, A.S.7
Ahmad, M.8
Cohn, D.H.9
Siddique, T.10
-
20
-
-
55649089437
-
Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study
-
Dai, J., Shi, D., Zhu, P., Qin, J., Ni, H., Xu, Y., Yao, C., Zhu, L., Zhu, H., Zhao, B. et al. (2008) Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study. Arthritis Res. Ther., 10, R126.
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Dai, J.1
Shi, D.2
Zhu, P.3
Qin, J.4
Ni, H.5
Xu, Y.6
Yao, C.7
Zhu, L.8
Zhu, H.9
Zhao, B.10
-
21
-
-
77956009674
-
Evidence of association between GDF5 polymorphisms and congenital dislocation of the hip in a Caucasian population
-
Rouault, K., Scotet, V., Autret, S., Gaucher, F., Dubrana, F., Tanguy, D., El Rassi, C.Y., Fenoll, B. and Ferec, C. (2010) Evidence of association between GDF5 polymorphisms and congenital dislocation of the hip in a Caucasian population. Osteoarthritis Cartilage, 18, 1144-1149.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 1144-1149
-
-
Rouault, K.1
Scotet, V.2
Autret, S.3
Gaucher, F.4
Dubrana, F.5
Tanguy, D.6
El Rassi, C.Y.7
Fenoll, B.8
Ferec, C.9
-
22
-
-
79953679565
-
GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women
-
Williams, F.M., Popham, M., Hart, D.J., de Schepper, E., Bierma-Zeinstra, S., Hofman, A., Uitterlinden, A.G., Arden, N.K., Cooper, C., Spector, T.D. et al. (2011) GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women. Arthritis Rheum., 63, 708-712.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 708-712
-
-
Williams, F.M.1
Popham, M.2
Hart, D.J.3
de Schepper, E.4
Bierma-Zeinstra, S.5
Hofman, A.6
Uitterlinden, A.G.7
Arden, N.K.8
Cooper, C.9
Spector, T.D.10
-
23
-
-
78649375679
-
Components of the transforming growth factor-β family and the pathogenesis of human Achilles tendon pathology-a genetic association study
-
Posthumus, M., Collins, M., Cook, J., Handley, C.J., Ribbans, W.J., Smith, R.K., Schwellnus, M.P. and Raleigh, S.M. (2010) Components of the transforming growth factor-(family and the pathogenesis of human Achilles tendon pathology-a genetic association study. Rheumatology (Oxford), 49, 2090-2097.
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 2090-2097
-
-
Posthumus, M.1
Collins, M.2
Cook, J.3
Handley, C.J.4
Ribbans, W.J.5
Smith, R.K.6
Schwellnus, M.P.7
Raleigh, S.M.8
-
24
-
-
80051687184
-
The polygenic profiles in participants with achilles tendinopathy and controls
-
Posthumus, M., Saunders, C., September, A.V. and Collins, M. (2011) The polygenic profiles in participants with achilles tendinopathy and controls. Br. J. Sports. Med., 45, 369.
-
(2011)
Br. J. Sports. Med.
, vol.45
, pp. 369
-
-
Posthumus, M.1
Saunders, C.2
September, A.V.3
Collins, M.4
-
25
-
-
67650074525
-
Functional analysis of the GDF5 regulatory polymorphism that is associated with OA susceptibility
-
Egli, R., Southam, L., Wilkins, J.M., Lorenzen, I., Pombo-Suarez, M., Gonzalez, A., Carr, A., Chapman, K. and Loughlin, J. (2009) Functional analysis of the GDF5 regulatory polymorphism that is associated with OA susceptibility. Arthritis Rhuematism, 60, 2055-2064.
-
(2009)
Arthritis Rhuematism
, vol.60
, pp. 2055-2064
-
-
Egli, R.1
Southam, L.2
Wilkins, J.M.3
Lorenzen, I.4
Pombo-Suarez, M.5
Gonzalez, A.6
Carr, A.7
Chapman, K.8
Loughlin, J.9
-
26
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango Allen, H., Estrada, K., Lettre, G., Berndt, S.I., Weedon, M.N., Rivadeneira, F., Willer, C.J., Jackson, A.U., Vedantam, S., Raychaudhuri, S. et al. (2010) Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature, 467, 832-838.
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
Berndt, S.I.4
Weedon, M.N.5
Rivadeneira, F.6
Willer, C.J.7
Jackson, A.U.8
Vedantam, S.9
Raychaudhuri, S.10
-
27
-
-
38649121127
-
Common variants in the GDF5-UQCC region are associated with variation in human height
-
Sanna, S., Jackson, A.U., Nagaraja, R., Willer, C.J., Chen, W.-M., Bonnycastle, L.L., Shen, H., Timpson, N., Lettre, G., Usala, G. et al. (2008) Common variants in the GDF5-UQCC region are associated with variation in human height. Nat. Genet., 40, 198-203.
-
(2008)
Nat. Genet.
, vol.40
, pp. 198-203
-
-
Sanna, S.1
Jackson, A.U.2
Nagaraja, R.3
Willer, C.J.4
Chen, W.-M.5
Bonnycastle, L.L.6
Shen, H.7
Timpson, N.8
Lettre, G.9
Usala, G.10
-
28
-
-
33847716756
-
Developmental failure of the intra-articular ligaments in mice with absence of growth differentiation factor 5
-
Harada, M., Takahara, M., Zhe, P., Otsuji, M., Iuchi, Y., Takagi, M. and Ogino, T. (2007) Developmental failure of the intra-articular ligaments in mice with absence of growth differentiation factor 5. Osteoarthritis Cartilage, 15, 468-474.
-
(2007)
Osteoarthritis Cartilage
, vol.15
, pp. 468-474
-
-
Harada, M.1
Takahara, M.2
Zhe, P.3
Otsuji, M.4
Iuchi, Y.5
Takagi, M.6
Ogino, T.7
-
29
-
-
0028232724
-
Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily
-
Storm, E.E., Huynh, T.V., Copeland, N.G., Jenkins, N.A., Kingsley, D.M. and Lee, S.J. (1994) Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily. Nature, 368, 639-643.
-
(1994)
Nature
, vol.368
, pp. 639-643
-
-
Storm, E.E.1
Huynh, T.V.2
Copeland, N.G.3
Jenkins, N.A.4
Kingsley, D.M.5
Lee, S.J.6
-
30
-
-
78650666914
-
GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes
-
Daans, M., Luyten, F.P. and Lories, R.J.U. (2011) GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes. Ann. Rheum. Dis., 70, 208-213.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 208-213
-
-
Daans, M.1
Luyten, F.P.2
Lories, R.J.U.3
-
31
-
-
61449135868
-
Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation
-
Cheung, K.S., Hashimoto, K., Yamada, N. and Roach, H.I. (2009) Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation. Rheumatol. Int., 29, 525-534.
-
(2009)
Rheumatol. Int.
, vol.29
, pp. 525-534
-
-
Cheung, K.S.1
Hashimoto, K.2
Yamada, N.3
Roach, H.I.4
-
32
-
-
65249106542
-
Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage
-
da Silva, M.A., Yamada, N., Clarke, N.M. and Roach, H.I. (2009) Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage. J. Orthop. Res., 27, 593-601.
-
(2009)
J. Orthop. Res.
, vol.27
, pp. 593-601
-
-
da Silva, M.A.1
Yamada, N.2
Clarke, N.M.3
Roach, H.I.4
-
33
-
-
26844518429
-
Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions
-
Roach, H.I., Yamada, N., Cheung, K.S., Tilley, S., Clarke, N.M., Oreffo, R.O., Kokubun, S. and Bronner, F. (2005) Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions. Arthritis. Rheum., 52, 3110-3124.
-
(2005)
Arthritis. Rheum.
, vol.52
, pp. 3110-3124
-
-
Roach, H.I.1
Yamada, N.2
Cheung, K.S.3
Tilley, S.4
Clarke, N.M.5
Oreffo, R.O.6
Kokubun, S.7
Bronner, F.8
-
34
-
-
77955436218
-
Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease
-
Scott, J.L., Gabrielides, C., Davidson, R.K., Swingler, T.E., Clark, I.M., Wallis, G.A., Boot-Handford, R.P., Kirkwood, T.B.L., Talyor, R.W. and Young, D.A. (2010) Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease. Ann. Rheum. Dis., 69, 1502-1510.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1502-1510
-
-
Scott, J.L.1
Gabrielides, C.2
Davidson, R.K.3
Swingler, T.E.4
Clark, I.M.5
Wallis, G.A.6
Boot-Handford, R.P.7
Kirkwood, T.B.L.8
Talyor, R.W.9
Young, D.A.10
-
35
-
-
0036856355
-
MethPrimer: designing primers for methylation PCRs
-
Li, L.-C. and Dahiya, R. (2002) MethPrimer: designing primers for methylation PCRs. Bioinformatics, 18, 1427-1431.
-
(2002)
Bioinformatics
, vol.18
, pp. 1427-1431
-
-
Li, L.-C.1
Dahiya, R.2
-
36
-
-
38449102144
-
Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
-
Klug, M. and Rehli, M. (2006) Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics, 1, 127-130.
-
(2006)
Epigenetics
, vol.1
, pp. 127-130
-
-
Klug, M.1
Rehli, M.2
-
37
-
-
0038664127
-
Identification and functional analysis of human transcriptional promoters
-
Trinklein, N.D., Aldred, S.J., Saldanha, A.J. and Myers, R.M. (2003) Identification and functional analysis of human transcriptional promoters. Genome Res., 13, 308-312.
-
(2003)
Genome Res.
, vol.13
, pp. 308-312
-
-
Trinklein, N.D.1
Aldred, S.J.2
Saldanha, A.J.3
Myers, R.M.4
-
38
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber, M., Hellmann, I., Stadler, M.B., Ramos, L., Paabo, S., Rebhan, M. and Schubeler, D. (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet., 39, 457-466.
-
(2007)
Nat. Genet.
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
39
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga, M.F., Ballestar, E., Paz, M.F., Ropero, S., Setien, F., Ballestar, M.L., Heine-Suñer, D., Cigudosa, J.C., Urioste, M., Benitez, J. et al. (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl Acad. Sci. USA, 102, 10604-10609.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Ropero, S.4
Setien, F.5
Ballestar, M.L.6
Heine-Suñer, D.7
Cigudosa, J.C.8
Urioste, M.9
Benitez, J.10
-
40
-
-
77955651636
-
Epigenetic alterations in aging
-
Gonzalo, S. (2010) Epigenetic alterations in aging. J. Appl. Physiol., 109, 586-597.
-
(2010)
J. Appl. Physiol.
, vol.109
, pp. 586-597
-
-
Gonzalo, S.1
-
41
-
-
59249107052
-
DNA methylation profiles in monozygotic and dizygotic twins
-
Kaminsky, Z.A., Tang, T., Wang, S.-C., Ptak, C., Oh, G.H.T., Wong, A.H.C., Feldcamp, L.A., Virtanen, C., Halfvarson, J., Tysk, C. et al. (2009) DNA methylation profiles in monozygotic and dizygotic twins. Nat. Genet., 41, 240-245.
-
(2009)
Nat. Genet.
, vol.41
, pp. 240-245
-
-
Kaminsky, Z.A.1
Tang, T.2
Wang, S.-C.3
Ptak, C.4
Oh, G.H.T.5
Wong, A.H.C.6
Feldcamp, L.A.7
Virtanen, C.8
Halfvarson, J.9
Tysk, C.10
-
42
-
-
79961202381
-
Genetic contributions to the association between adult height and testicular germ cell tumors
-
doi: 10.1093/ije/dyq260
-
Cook, M.B., Chia, V.M., Berndt, S.I., Graubard, B.I., Chanock, S.J., Rubertone, M.V., Erickson, R.L., Hayes, R.B. and McGlynn, K.A. (2011) Genetic contributions to the association between adult height and testicular germ cell tumors. Int. J. Epidemiol. doi: 10.1093/ije/dyq260
-
(2011)
Int. J. Epidemiol.
-
-
Cook, M.B.1
Chia, V.M.2
Berndt, S.I.3
Graubard, B.I.4
Chanock, S.J.5
Rubertone, M.V.6
Erickson, R.L.7
Hayes, R.B.8
McGlynn, K.A.9
-
43
-
-
45849127657
-
Intra-individual Change Over Time in DNA Methylation With Familial Clustering
-
Bjornsson, H.T., Sigurdsson, M.I., Fallin, M.D., Irizarry, R.A., Aspelund, T., Cui, H., Yu, W., Rongione, M.A., Ekström, T.J., Harris, T.B. et al. (2008) Intra-individual Change Over Time in DNA Methylation With Familial Clustering. JAMA, 299, 2877-2883.
-
(2008)
JAMA
, vol.299
, pp. 2877-2883
-
-
Bjornsson, H.T.1
Sigurdsson, M.I.2
Fallin, M.D.3
Irizarry, R.A.4
Aspelund, T.5
Cui, H.6
Yu, W.7
Rongione, M.A.8
Ekström, T.J.9
Harris, T.B.10
-
44
-
-
4444375474
-
Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study
-
Fuke, C., Shimabukuro, M., Petronis, A., Sugimoto, J., Oda, T., Miura, K., Miyazaki, T., Ogura, C., Okazaki, Y. and Jinno, Y. (2004) Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study. Ann. Hum. Genet., 68, 196-204.
-
(2004)
Ann. Hum. Genet.
, vol.68
, pp. 196-204
-
-
Fuke, C.1
Shimabukuro, M.2
Petronis, A.3
Sugimoto, J.4
Oda, T.5
Miura, K.6
Miyazaki, T.7
Ogura, C.8
Okazaki, Y.9
Jinno, Y.10
-
45
-
-
0020638422
-
DNA methylation decreases in aging but not in immortal cells
-
Wilson, V.L. and Jones, P.A. (1983) DNA methylation decreases in aging but not in immortal cells. Science, 220, 1055-1057.
-
(1983)
Science
, vol.220
, pp. 1055-1057
-
-
Wilson, V.L.1
Jones, P.A.2
-
46
-
-
0023664725
-
Genomic 5-methyldeoxycytidine decreases with age
-
Wilson, V.L., Smith, R.A., Ma, S. and Cutler, R.G. (1987) Genomic 5-methyldeoxycytidine decreases with age. J. Biol. Chem., 262, 9948-9951.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9948-9951
-
-
Wilson, V.L.1
Smith, R.A.2
Ma, S.3
Cutler, R.G.4
-
47
-
-
3242663659
-
An integrated epigenetic and genetic approach to common human disease
-
Bjornsson, H.T., Daniele Fallin, M. and Feinberg, A.P. (2004) An integrated epigenetic and genetic approach to common human disease. Trends Genet., 20, 350-358.
-
(2004)
Trends Genet.
, vol.20
, pp. 350-358
-
-
Bjornsson, H.T.1
Daniele Fallin, M.2
Feinberg, A.P.3
-
48
-
-
61549140408
-
DNA methylation is not responsible for p21WAF1/CIP1 down-regulation in osteoarthritic chondrocytes
-
Sesselmann, S., Soder, S., Voigt, R., Haag, J., Grogan, S.P. and Aigner, T. (2009) DNA methylation is not responsible for p21WAF1/CIP1 down-regulation in osteoarthritic chondrocytes. Osteoarthritis Cartilage, 17, 507-512.
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 507-512
-
-
Sesselmann, S.1
Soder, S.2
Voigt, R.3
Haag, J.4
Grogan, S.P.5
Aigner, T.6
-
49
-
-
61549102182
-
Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage
-
Loeser, R.F., Im, H.J., Richardson, B., Lu, Q. and Chubinskaya, S. (2009) Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage. Osteoarthritis Cartilage, 17, 513-517.
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 513-517
-
-
Loeser, R.F.1
Im, H.J.2
Richardson, B.3
Lu, Q.4
Chubinskaya, S.5
-
50
-
-
79952818200
-
Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus
-
Dodd, A.W., Rodriguez-Fontenla, C., Calaza, M., Carr, A., Gomez-Reino, J.J., Tsezou, A., Reynard, L.N., Gonzalez, A. and Loughlin, J. (2011) Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus. Osteoarthritis Cartilage, 19, 430-434.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 430-434
-
-
Dodd, A.W.1
Rodriguez-Fontenla, C.2
Calaza, M.3
Carr, A.4
Gomez-Reino, J.J.5
Tsezou, A.6
Reynard, L.N.7
Gonzalez, A.8
Loughlin, J.9
-
51
-
-
27744577751
-
BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing
-
Bock, C., Reither, S., Mikeska, T., Paulsen, M., Walter, Jr. and Lengauer, T. (2005) BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics, 21, 4067-4068.
-
(2005)
Bioinformatics
, vol.21
, pp. 4067-4068
-
-
Bock, C.1
Reither, S.2
Mikeska, T.3
Paulsen, M.4
Walter, J.R.5
Lengauer, T.6
-
52
-
-
79956347514
-
Folate depletion during pregnancy and lactation reduces genomic DNA methylation in murine adult offspring
-
McKay, J., Waltham, K., Williams, E. and Mathers, J. (2011) Folate depletion during pregnancy and lactation reduces genomic DNA methylation in murine adult offspring. Genes Nutrition, 6, 189-196.
-
(2011)
Genes Nutrition
, vol.6
, pp. 189-196
-
-
McKay, J.1
Waltham, K.2
Williams, E.3
Mathers, J.4
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