Genes relevant with osteoarthritis by comparison gene expression profiles of synovial membrane of osteoarthritis patients at different stages

European Review for Medical and Pharmacological Sciences

Volumn 18, Issue 3, 2014, Pages 431-439

  Ma, C H ^a   Lv, Q ^b   Cao, Y ^a   Wang, Q ^a   Zhou, X K ^a   Ye, B W ^a   Yi, C Q ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

Differentially expressed genes; Gene therapy; Osteoarthritis

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BONE MORPHOGENETIC PROTEIN 5; CYCLOOXYGENASE 2; CYTOCHROME P450 2E1; RAC2 PROTEIN; TOLL LIKE RECEPTOR; TRANSCRIPTOME;

ACR GENE; ADRB2 GENE; APOLD1 GENE; ARSG GENE; ARTICLE; BONE; BTBD11 GENE; C20ORF46 GENE; CARTILAGE; CARTILAGE CELL; CILP2 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; CRIP2 GENE; CYP2R1 GENE; CYTH2 GENE; DISEASE SEVERITY; DOWN REGULATION; EBF2 GENE; EFEMP1 GENE; ELL2 GENE; FAM129A GENE; GBGT1 GENE; GENE; GENE EXPRESSION; GENE NUMBER; HAUS3 GENE; HCG26 GENE; HUMAN; IGHM GENE; IGKV1 5 GENE; IGKV4 1 GENE; IGLV1 36 GENE; IGLV2 23 GENE; IMMUNE SYSTEM; LOC100129034 GENE; LOC100507560 GENE; LTBP2 GENE; LZTS2 GENE; MAN2A1 GENE; MPI GENE; NUCLEOTIDE SEQUENCE; OLFML2A GENE; OSTEOARTHRITIS; PAMR1 GENE; PATHOGENESIS; PBLD GENE; PDZRN4 GENE; PLEKHG4 GENE; PROTEIN GLYCOSYLATION; PRR14 GENE; RAI14 GENE; RNF150 GENE; ROR2 GENE; SEC24A GENE; SERPINA3 GENE; SLN GENE; SPATA18 GENE; STT3A GENE; SYNOVIUM; TNIK GENE; TRIP10 GENE; UPREGULATION; WNT SIGNALING PATHWAY; ZIC1 GENE; DISEASE COURSE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; GENETICS; KNEE OSTEOARTHRITIS; METABOLISM; MICROARRAY ANALYSIS; MULTIGENE FAMILY; PATHOLOGY;

DISEASE PROGRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENETIC ASSOCIATION STUDIES; HUMANS; MICROARRAY ANALYSIS; MULTIGENE FAMILY; OSTEOARTHRITIS, KNEE; SYNOVIAL MEMBRANE; TRANSCRIPTOME;

EID: 84896996773     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. GILLAM MH, LIE SA, SALTER A, FURNES O, GRAVES SE, HAVELIN LI, RYAN P. The progression of end-stage osteoarthritis: analysis of data from the Australian and Norwegian joint replacement registries using a multi-state model. Osteoarthritis Cartilage 2013; 21: 405-412.
2. TAKAHASHI D, IWASAKI N, KON S, MATSUI Y, MAJIMA T, MINAMI A, UEDE T. Down-regulation of cathepsin K in synovium leads to progression of osteoarthritis in rabbits. Arthritis Rheum 2009; 60: 2372-2380.
3. PELLETIER JP, KAPOOR M, FAHMI H, LAJEUNESSE D, BLESIUS A, MAILLET J, MARTEL-PELLETIER J. Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1beta in the synovium. Ann Rheum Dis 2013; 72: 250-257.
4. FIRESTEIN GS. Evolving concepts of rheumatoid arthritis. Nature 2003; 423: 356-361.
5. SETO H, KAMEKURA S, MIURA T, YAMAMOTO A, CHIKUDA H, OGATA T, HIRAOKA H, ODA H, NAKAMURA K, KUROSAWA H, CHUG UI, KAWAGUCHI H, TANAKA S. Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts. J Clin Invest 2004; 113: 718-726.
6. TSUNEYOSHI Y, TANAKA M, NAGAI T, SUNAHARA N, MATSUDA T, SONODA T, IJIRI K, KOMIYA S, MATSUYAMA T. Functional folate receptor beta-expressing macrophages in osteoarthritis synovium and their M1/M2 expression profiles. Scand J Rheumatol 2012; 41: 132-140.
7. SUURMOND J, DORJEE AL, BOON MR, KNOL EF, HUIZINGA TW, TOES RE, SCHUERWEGH AJ. Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and-negative rheumatoid arthritis and osteoarthritis synovium. Arthritis Res Ther 2011; 13: R150.
8. LUO XY, YANG MH, WU FX, WU LJ, CHEN L, TANG Z, LIU NT, ZENG XF, GUAN JL, YUAN GH. Vitamin D receptor gene BsmI polymorphism B allele, but not BB genotype, is associated with systemic lupus erythematosus in a Han Chinese population. Lupus 2012; 21: 53-59.
9. ZHANG Q, CHENG B, YANG C-X, GE H-A. Interaction relationships of osteoarthritis and rheumatoid arthritis related genes. Eur Rev Med Pharmacol Sci 2014; 18: 179-184.
10. ZHANG B, XIE QG, QUAN Y, PAN XM. Expression profiling based on graph-clustering approach to determine osteoarthritis related pathway. Eur Rev Med Pharmacol Sci 2013; 17: 2097-2102.
11. WANG Q, ROZELLE AL, LEPUS CM, SCANZELLO CR, SONG JJ, LARSEN DM, CRISH JF, BEBEK G, RITTER SY, LINDSTROM TM, HWANG I, WONG HH, PUNZI L, ENCARNACION A, SHAMLOO M, GOODMAN SB, WYSS-CORAY T, GOLDRING SR, BANDA NK, THURMAN JM, GOBEZIE R, CROW MK, HOLERS VM, LEE DM, ROBINSON WH. Identification of a central role for complement in osteoarthritis. Nat Med 2011; 17: 1674-1679.
12. IRIZARRY RA, BOLSTAD BM, COLLIN F, COPE LM, HOBBS B, SPEED TP. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003; 31: e15.
13. TUSHER VG, TIBSHIRANI R, CHU G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001; 98: 5116-5121.
14. ALLOCCO DJ, KOHANE IS, BUTTE AJ. Quantifying the relationship between co-expression, co-regulation and gene function. BMC Bioinformatics 2004; 5: 18.
15. BADER GD, HOGUE CW. An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics 2003; 4: 2.
16. HUANG DA W, SHERMAN BT, LEMPICKI RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009; 37: 1-13.
17. SHARAN R, ULITSKY I, SHAMIR R. Network-based prediction of protein function.Mol Syst Biol 2007; 3: 88.
18. KUSAOI M, YAMAJI K, MURAYAMA G, YASUI M, YAMADA R, HISHINUMA R, NEMOTO T, HOHTATSU K, KAGEYAMA M, KAWAMOTO T, SUGIMOTO K, SEKIYA F, KON T, OGASAWARA M, KEMPE K, TSUDA H, TAKASAKI Y. Gene expression analysis using a high-resolution DNA mi-croarray of peripheral whole blood immediately before and after leukocytapheresis for rheumatoid arthritis. Ther Apher Dial 2012; 16: 456-466.
19. TAKAYANAGI H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 2007; 7: 292-304.
20. LORENZO J, HOROWITZ M, CHOI Y. Osteoimmunology: interactions of the bone and immune system. Endocr Rev 2008; 29: 403-440.
21. ZHAO C, INOUE J, IMOTO I, OTSUKI T, IIDA S, UEDA R, INAZAWA J. POU2AF1, an amplification target at 11q23, promotes growth of multiple myeloma cells by directly regulating expression of a B-cell maturation factor, TNFRSF17. Oncogene 2008; 27: 63-75.
22. GRAVALLESE EM, GALSON DL, GOLDRING SR, AURON PE. The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption. Arthritis Res 2001; 3: 6-12.
23. YASUDA H, SHIMA N, NAKAGAWA N, YAMAGUCHI K, KINOSAKI M, MOCHIZUKI S, TOMOYASU A, YANO K, GOTO M, MURAKAMI A, TSUDA E, MORINAGA T, HIGASHIO K, UDAGAWA N, TAKAHASHI N, SUDA T. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci U S A 1998; 95: 3597-3602.
24. VANDOOREN B, CANTAERT T, NOORDENBOS T, TAK PP, BAETEN D. The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation. Arthritis Rheum 2008; 58: 718-729.
25. TAKAYANAGI H, IIZUKA H, JUJI T, NAKAGAWA T, YAMAMOTO A, MIYAZAKI T, KOSHIHARA Y, ODA H, NAKAMURA K, TANAKA S. Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000; 43: 259-269.
26. RITCHLIN CT, SCHWARZ EM, O'KEEFE RJ, LOONEY RJ. RANK, RANKL and OPG in inflammatory arthritis and periprosthetic osteolysis. J Musculoskelet Neuronal Interact 2004; 4: 276-284.
27. CHUNG EY, PSATHAS JN, YU D, LI Y, WEISS MJ, THOMASTIKHONENKO A. CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis. J Clin Invest; 122: 2257-2266.
28. TOWNSEND MJ, MONROE JG, CHAN AC. B-cell targeted therapies in human autoimmune diseases: an updated perspective. Immunol Rev 2010; 237: 264-283.
29. KOMORI T. Regulation of skeletal development by the Runx family of transcription factors. J Cell Biochem 2005; 95: 445-453.
30. KOBAYASHI T, KRONENBERG H. Minireview: transcriptional regulation in development of bone. Endocrinology 2005; 146: 1012-1017.
31. WANG X, MANNER PA, HORNER A, SHUM L, TUAN RS, NUCKOLLS GH. Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic car tilage. Osteoar thritis Car tilage 2004; 12: 963-973.
32. HOPWOOD B, TSYKIN A, FINDLAY DM, FAZZALARI NL. Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factorbeta/ bone morphogenic protein signalling. Arthritis Res Ther 2007; 9: R100.
33. MATSUHASHI T, IWASAKI N, NAKAGAWA H, HATO M, KUROGOCHI M, MAJIMA T, MINAMI A, NISHIMURA SI. Alteration of N-glycans related to articular cartilage deterioration after anterior cruciate ligament transection in rabbits. Osteoarthritis Cartilage 2008; 16: 772-778.
34. URITA A, MATSUHASHI T, ONODERA T, NAKAGAWA H, HATO M, AMANO M, SEITO N, MINAMI A, NISHIMURA S, IWASAKI N. Alterations of high-mannose type N-glycosylation in human and mouse osteoarthritis cartilage. Arthritis Rheum 2011; 63: 3428-3438.
35. ROOS EM, HERZOG W, BLOCK JA, BENNELL KL. Muscle weakness, afferent sensory dysfunction and exercise in knee osteoarthritis. Nat Rev Rheumatol 2010; 7: 57-63.
36. SLEMENDA C, HEILMAN DK, BRANDT KD, KATZ BP, MAZZUCA SA, BRAUNSTEIN EM, BYRD D. Reduced quadriceps strength relative to body weight: a risk factor for knee osteoarthritis in women? Arthritis Rheum 1998; 41: 1951-1959.
37. SEGAL NA, TORNER JC, FELSON D, NIU J, SHARMA L, LEWIS CE, NEVITT M. Effect of thigh strength on incident radiographic and symptomatic knee osteoar thritis in a longitudinal cohort. Arthritis Rheum 2009; 61: 1210-1217.
38. VELASCO J, ZARRABEITIA MT, PRIETO JR, PEREZ-CASTRILLON JL, PEREZ-AGUILAR MD, PEREZ-NUNEZ MI, SANUDO C, HERNANDEZ-ELENA J, CALVO I, ORTIZ F, GONZALEZMACIAS J, RIANCHO JA.Wnt pathway genes in osteoporosis and osteoarthritis: differential expression and genetic association study. Osteoporos Int 2010; 21: 109-118.
39. DELL'ACCIO F, DE BARI C, ELTAWIL NM, VANHUMMELEN P, PITZALIS C. Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis. Arthritis Rheum 2008; 58: 1410-1421.
40. BLOM AB, BROCKBANK SM, VAN LENT PL, VAN BEUNINGEN HM, GEURTS J, TAKAHASHI N, VAN DER KRAAN PM, VAN DE LOO FA, SCHREURS BW, CLEMENTS K, NEWHAM P, VAN DEN BERG WB. Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1. Arthritis Rheum 2009; 60: 501-512.
41. GOLDRING MB,MARCU KB. Cartilage homeostasis in health and rheumatic diseases. Arthritis Res Ther 2009; 11: 224.
42. YANG HY, LEE HS, LEE CH, FANG WH, CHEN HC, SALTER DM, SU SL. Association of a functional polymorphism in the promoter region of TLR-3 with osteoarthritis: A two-stage case-control study. J Orthop Res 2013; 31: 680-685.