Vitamin D receptor gene BsmI polymorphism B allele, but not BB genotype, is associated with systemic lupus erythematosus in a Han Chinese population

Lupus

Volumn 21, Issue 1, 2012, Pages 53-59

  Luo, X Y ^a   Yang, M H ^a   Wu, F X ^a   Wu, L J ^b   Chen, L ^a   Tang, Z ^a   Liu, N T ^c   Zeng, X F ^d   Guan, J L ^e   Yuan, G H ^a  

^a AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

^b PEOPLE S HOSPITAL OF XINJIANG UYGUR AUTONOMOUS REGION   (China)

^c Suining Municipal People's Hospital   (China)

^d PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^e SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

BsmI; polymorphism; systemic lupus erythematosus; vitamin D receptor (VDR)

Indexed keywords

MESSENGER RNA; NUCLEOSOME ANTIBODY; VITAMIN D RECEPTOR;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADOLESCENT; ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; ETHNIC GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL; YOUNG ADULT;

EID: 83655192297     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203311422709     Document Type: Article

References (28)

1. Lettre G, Rioux JD. Autoimmune diseases: insights from genome-wide association studies. Hum Mol Genet. 2008 ; 17 (R2). R116 - R121
2. Tsao BP. An update on genetic studies of systemic lupus erythematosus. Curr Rheumatol Rep. 2002 ; 4: 359-367
3. Lemire JM, Archer DC, Beck L, Spiegeberg HL. Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions. J Nutr. 1995 ; 125 (Suppl). 1704-1708
4. Baker AR, McDonnell DP, Hughes M, et al. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci U S A. 1988 ; 85: 3294-3298
5. Miyamoto K, Kesterson RA, Yamamoto H, et al. Structural organization of the human vitamin D receptor chromosomal gene and its promoter. Mol Endocrinol. 1997 ; 11: 1165-1179 (Pubitemid 27278838)
6. Strugnell SA, DeLuca HF. The Vitamin D receptor structure and transcriptional activation. Proc Soc Exp Biol Med. 1997 ; 215: 223-228
7. Morrison NA, Qi JC, Tokita A, et al. Prediction of bone density from vitamin D receptor alleles. Nature. 1994 ; 367: 284-287 (Pubitemid 24051146)
8. Eisman JA. Genetics of osteoporosis. Endocr Rev. 1999 ; 20: 788-804 (Pubitemid 30647074)
9. Carling T, Rastad J, Akerstrom G, Westin G. Vitamin D receptor (VDR) and parathyroid hormone messenger ribonucleic acid levels correspond to polymorphic VDR alleles in human parathyroid tumors. J Clin Endocrinol Metab. 1998 ; 83: 2255-2259 (Pubitemid 28503010)
10. Ingles SA, Coetzee GA, Ross RK, et al. Association of prostate cancer with vitamin D receptor haplotypes in African-Americans. Cancer Res. 1998 ; 58: 1620-1623 (Pubitemid 28215081)
11. Ozaki Y, Nomura S, Nagahama M, Yoshimura C, Kagawa H, Fukuhara S. Vitamin-D receptor genotype and renal disorder in Japanese patients with systemic lupus erythematosus. Nephron. 2000 ; 85: 86-91 (Pubitemid 30242835)
12. Sakulpipatsin W, Verasertniyom O, Nantiruj K, Totemchokchyakarn K, Lertsrisatit P, Janwityanujit S. Vitamin D receptor gene BsmI polymorphisms in Thai patients with systemic lupus erythematosus. Arthritis Res Ther. 2006 ; 8: R48 - R48
13. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997 ; 40: 1725-1725
14. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum. 1992 ; 35 (6). 630-640
15. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001 ; 25: 402-408 (Pubitemid 34164012)
16. Sullivan KE. Genetics of systemic lupus erythematosus: clinical implications. Rheum Dis Clin North Am. 2000 ; 26: 229-256 (Pubitemid 30198758)
17. Voll RE, Roth EA, Girkontaite I, et al. Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce doublestranded DNA antibody production. Arthritis Rheum. 1997 ; 40: 2162-2171 (Pubitemid 28016412)
18. Arnson Y, Amital H, Shoenfeld Y. Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Ann Rheum Dis. 2007 ; 66: 1137-1142 (Pubitemid 47309727)
19. Evans RM. The steroid and thyroid hormone receptor superfamily. Science. 1988 ; 240: 889-895
20. Boonstra A, Barrat FJ, Crain C, et al. 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol. 2001 ; 167: 4974-4980 (Pubitemid 33009728)
21. Takeuchi A, Reddy GS, Kobayashi T, et al. Nuclear factor of activated T cells (NFAT) as a molecular target for 1alpha,25-dihydroxyvitamin D3-mediated effects. J Immunol. 1998 ; 160: 209-218 (Pubitemid 28116731)
22. Cantorna MT, Woodward WD, Hayes CE, DeLuca HF. 1,25-dihydroxyvitamin D3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-beta 1 and IL-4. J Immunol. 1998 ; 160: 5314-5319 (Pubitemid 28267819)
23. Skjodt H, Hughes DE, Dobson PR, Russell RG. Constitutive and inducible expression of HLA class II determinants by human osteoblast-like cells in vitro. J Clin Invest. 1990 ; 85: 1421-1426 (Pubitemid 20176433)
24. Huang CM, Wu MC, Wu JY, Tsai FJ. Association of vitamin D receptor gene BsmI polymorphisms in Chinese patients with systemic lupus erythematosus. Lupus. 2002 ; 11: 31-34
25. Abbasi M, Rezaieyazdi Z, Afshari JT, Hatef M, Sahebari M, Saadati N. Lack of association of vitamin D receptor gene BsmI polymorphisms in patients with systemic lupus erythematosus. Rheumatol Int. 2010 ; 30: 1537-1539
26. Ogunkolade BW, Boucher BJ, Prahl JM, et al. Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians. Diabetes. 2002 ; 51: 2294-2300 (Pubitemid 34729038)
27. Ohtera K, Ishii S, Matsuyama T. Influence of the vitamin D receptor alleles on human osteoblast-like cells. J Bone Joint Surg Br. 2001 ; 83: 134-138 (Pubitemid 32170979)
28. Mocharla H, Butch AW, Pappas AA, et al. Quantification of vitamin D receptor mRNA by competitive polymerase chain reaction in PBMC: lack of correspondence with common allelic variants. J Bone Miner Res. 1997 ; 12: 726-733 (Pubitemid 27200323)