메뉴 건너뛰기




Volumn 58, Issue 3, 2008, Pages 718-729

The abundant synovial expression of the RANK/RANKL/osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ETANERCEPT; INFLIXIMAB; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

EID: 40549088214     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.23290     Document Type: Article
Times cited : (77)

References (36)
  • 3
    • 33745055952 scopus 로고    scopus 로고
    • Immunohistochemical analysis of hip arthritis in ankylosing spondylitis: Evaluation of the bone-cartilage interface and subchondral bone marrow
    • Appel H, Kuhne M, Spiekermann S, Kohler D, Zacher J, Stein H, et al. Immunohistochemical analysis of hip arthritis in ankylosing spondylitis: evaluation of the bone-cartilage interface and subchondral bone marrow. Arthritis Rheum 2006;54:1805-13.
    • (2006) Arthritis Rheum , vol.54 , pp. 1805-1813
    • Appel, H.1    Kuhne, M.2    Spiekermann, S.3    Kohler, D.4    Zacher, J.5    Stein, H.6
  • 4
    • 33749340335 scopus 로고    scopus 로고
    • Immunohistologic analysis of zygapophyseal joints in patients with ankylosing spondylitis
    • Appel H, Kuhne M, Spiekermann S, Ebhart H, Grozdanovic Z, Kohler D, et al. Immunohistologic analysis of zygapophyseal joints in patients with ankylosing spondylitis. Arthritis Rheum 2006;54:2845-51.
    • (2006) Arthritis Rheum , vol.54 , pp. 2845-2851
    • Appel, H.1    Kuhne, M.2    Spiekermann, S.3    Ebhart, H.4    Grozdanovic, Z.5    Kohler, D.6
  • 5
    • 9244252016 scopus 로고    scopus 로고
    • The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling
    • Theoleyre S, Wittrant Y, Tat SK, Fortun Y, Redini F, Heymann D. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 2004;15:457-75.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 457-475
    • Theoleyre, S.1    Wittrant, Y.2    Tat, S.K.3    Fortun, Y.4    Redini, F.5    Heymann, D.6
  • 6
    • 0031894140 scopus 로고    scopus 로고
    • Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis
    • Gravallese EM, Harada Y, Wang JT, Gorn AH, Thornhill TS, Goldring SR. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol 1998;152:943-51.
    • (1998) Am J Pathol , vol.152 , pp. 943-951
    • Gravallese, E.M.1    Harada, Y.2    Wang, J.T.3    Gorn, A.H.4    Thornhill, T.S.5    Goldring, S.R.6
  • 8
    • 17444452820 scopus 로고    scopus 로고
    • Activated human T cells directly induce osteoclastogenesis from human monocytes: Possible role of T cells in bone destruction in rheumatoid arthritis patients
    • Kotake S, Udagawa N, Hakoda M, Mogi M, Yano K, Tsuda E, et al. Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum 2001;44:1003-12.
    • (2001) Arthritis Rheum , vol.44 , pp. 1003-1012
    • Kotake, S.1    Udagawa, N.2    Hakoda, M.3    Mogi, M.4    Yano, K.5    Tsuda, E.6
  • 9
    • 0034121039 scopus 로고    scopus 로고
    • Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis
    • Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, et al. Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000;43:259-69.
    • (2000) Arthritis Rheum , vol.43 , pp. 259-269
    • Takayanagi, H.1    Iizuka, H.2    Juji, T.3    Nakagawa, T.4    Yamamoto, A.5    Miyazaki, T.6
  • 10
    • 0037364369 scopus 로고    scopus 로고
    • Mechanisms of TNF-α and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis
    • Ritchlin CT, Haas-Smith SA, Li P, Hicks DG, Schwarz EM. Mechanisms of TNF-α and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis. J Clin Invest 2003;111:821-31.
    • (2003) J Clin Invest , vol.111 , pp. 821-831
    • Ritchlin, C.T.1    Haas-Smith, S.A.2    Li, P.3    Hicks, D.G.4    Schwarz, E.M.5
  • 11
    • 0036892685 scopus 로고    scopus 로고
    • Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: Semi-quantitative and quantitative analysis
    • Crotti TN, Smith MD, Weedon H, Ahern MJ, Findlay DM, Kraan M, et al. Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: semi-quantitative and quantitative analysis. Ann Rheum Dis 2002;61:1047-54.
    • (2002) Ann Rheum Dis , vol.61 , pp. 1047-1054
    • Crotti, T.N.1    Smith, M.D.2    Weedon, H.3    Ahern, M.J.4    Findlay, D.M.5    Kraan, M.6
  • 12
    • 0037242711 scopus 로고    scopus 로고
    • Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls
    • Haynes DR, Barg E, Crotti TN, Holding C, Weedon H, Atkins GJ, et al. Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls. Rheumatology 2003;42:123-34.
    • (2003) Rheumatology , vol.42 , pp. 123-134
    • Haynes, D.R.1    Barg, E.2    Crotti, T.N.3    Holding, C.4    Weedon, H.5    Atkins, G.J.6
  • 13
    • 33748068083 scopus 로고    scopus 로고
    • RANK expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone
    • Atkins GJ, Kostakis P, Vincent C, Farrugia AN, Houchins JP, Findlay DM, et al. RANK expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone. Bone Miner Res 2006;21:1339-49.
    • (2006) Bone Miner Res , vol.21 , pp. 1339-1349
    • Atkins, G.J.1    Kostakis, P.2    Vincent, C.3    Farrugia, A.N.4    Houchins, J.P.5    Findlay, D.M.6
  • 14
    • 0026003027 scopus 로고
    • The European Spondyloarthropathy Study Group preliminary criteria for the classification of spondyloarthropathy
    • Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondyloarthropathy Study Group preliminary criteria for the classification of spondyloarthropathy. Arthritis Rheum 1991;34:1218-27.
    • (1991) Arthritis Rheum , vol.34 , pp. 1218-1227
    • Dougados, M.1    van der Linden, S.2    Juhlin, R.3    Huitfeldt, B.4    Amor, B.5    Calin, A.6
  • 15
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
    • (1988) Arthritis Rheum , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3    McShane, D.J.4    Fries, J.F.5    Cooper, N.S.6
  • 16
    • 0033396977 scopus 로고    scopus 로고
    • Needle arthroscopy of the knee with synovial biopsy sampling: Technical experience in 150 patients
    • Baeten D, Van den Bosch F, Elewaut D, Stuer A, Veys EM, De Keyser F. Needle arthroscopy of the knee with synovial biopsy sampling: technical experience in 150 patients. Clin Rheumatol 1999;18:434-41.
    • (1999) Clin Rheumatol , vol.18 , pp. 434-441
    • Baeten, D.1    Van den Bosch, F.2    Elewaut, D.3    Stuer, A.4    Veys, E.M.5    De Keyser, F.6
  • 17
    • 0033637389 scopus 로고    scopus 로고
    • Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: Influence of disease duration and activity
    • Baeten D, Demetter P, Cuvelier C, Van Den Bosch F, Kruithof E, Van Damme N, et al. Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: influence of disease duration and activity. Ann Rheum Dis 2000;59:945-53.
    • (2000) Ann Rheum Dis , vol.59 , pp. 945-953
    • Baeten, D.1    Demetter, P.2    Cuvelier, C.3    Van Den Bosch, F.4    Kruithof, E.5    Van Damme, N.6
  • 18
    • 0035150659 scopus 로고    scopus 로고
    • Immunomodulatory effects of anti-tumor necrosis factor α therapy on synovium in spondylarthropathy: Histologic findings in eight patients from an open-label pilot study
    • Baeten D, Kruithof E, Van den Bosch F, Demetter P, Van Damme N, Cuvelier C, et al. Immunomodulatory effects of anti-tumor necrosis factor α therapy on synovium in spondylarthropathy: histologic findings in eight patients from an open-label pilot study. Arthritis Rheum 2001;44:186-95.
    • (2001) Arthritis Rheum , vol.44 , pp. 186-195
    • Baeten, D.1    Kruithof, E.2    Van den Bosch, F.3    Demetter, P.4    Van Damme, N.5    Cuvelier, C.6
  • 19
    • 29144437814 scopus 로고    scopus 로고
    • Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies
    • Kruithof E, De Rycke L, Roth J, Mielants H, Van den Bosch F, De Keyser F, et al. Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies. Arthritis Rheum 2005;52:3898-909.
    • (2005) Arthritis Rheum , vol.52 , pp. 3898-3909
    • Kruithof, E.1    De Rycke, L.2    Roth, J.3    Mielants, H.4    Van den Bosch, F.5    De Keyser, F.6
  • 22
    • 20544446895 scopus 로고    scopus 로고
    • Association of osteoprotegerin with human abdominal aortic aneurysm progression
    • Moran CS, McCann M, Karan M, Norman P, Ketheesan N, Golledge J. Association of osteoprotegerin with human abdominal aortic aneurysm progression. Circulation 2005;111:3119-25.
    • (2005) Circulation , vol.111 , pp. 3119-3125
    • Moran, C.S.1    McCann, M.2    Karan, M.3    Norman, P.4    Ketheesan, N.5    Golledge, J.6
  • 23
    • 33749604848 scopus 로고    scopus 로고
    • RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis
    • Pettit AR, Walsh NC, Manning C, Goldring SR, Gravallese EM. RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis. Rheumatology 2006;45:1068-76.
    • (2006) Rheumatology , vol.45 , pp. 1068-1076
    • Pettit, A.R.1    Walsh, N.C.2    Manning, C.3    Goldring, S.R.4    Gravallese, E.M.5
  • 24
    • 4444242688 scopus 로고    scopus 로고
    • Diagnostic classification of spondylarthropathy and rheumatoid arthritis by synovial histopathology: A prospective study in 154 consecutive patients
    • Baeten D, Kruithof E, De Rycke L, Vandooren B, Wyns B, Boullart L, et al. Diagnostic classification of spondylarthropathy and rheumatoid arthritis by synovial histopathology: a prospective study in 154 consecutive patients. Arthritis Rheum 2004;50:2931-41.
    • (2004) Arthritis Rheum , vol.50 , pp. 2931-2941
    • Baeten, D.1    Kruithof, E.2    De Rycke, L.3    Vandooren, B.4    Wyns, B.5    Boullart, L.6
  • 25
    • 0035091547 scopus 로고    scopus 로고
    • Measurement of cytokine and adhesion molecule expression in synovial tissue by digital image analysis
    • Kraan MC, Smith MD, Weedon H, Ahern MJ, Breedveld FC, Tak PP. Measurement of cytokine and adhesion molecule expression in synovial tissue by digital image analysis. Ann Rheum Dis 2001;60:296-8.
    • (2001) Ann Rheum Dis , vol.60 , pp. 296-298
    • Kraan, M.C.1    Smith, M.D.2    Weedon, H.3    Ahern, M.J.4    Breedveld, F.C.5    Tak, P.P.6
  • 26
    • 0642364978 scopus 로고    scopus 로고
    • RANKL regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
    • Kim HH, Shin HS, Kwak HJ, Ahn KY, Kim JH, Lee HJ, et al. RANKL regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. FASEB J 2003;17:2163-5.
    • (2003) FASEB J , vol.17 , pp. 2163-2165
    • Kim, H.H.1    Shin, H.S.2    Kwak, H.J.3    Ahn, K.Y.4    Kim, J.H.5    Lee, H.J.6
  • 27
    • 33745024234 scopus 로고    scopus 로고
    • CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-mediated osteoclastogenesis: Evidence of NF-κB-dependent, CD40-mediated bone destruction in rheumatoid arthritis
    • Lee HY, Jeon HS, Song EK, Han MK, Park SI, Lee SI, et al. CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-mediated osteoclastogenesis: evidence of NF-κB-dependent, CD40-mediated bone destruction in rheumatoid arthritis. Arthritis Rheum 2006;54:1747-58.
    • (2006) Arthritis Rheum , vol.54 , pp. 1747-1758
    • Lee, H.Y.1    Jeon, H.S.2    Song, E.K.3    Han, M.K.4    Park, S.I.5    Lee, S.I.6
  • 28
    • 33947497852 scopus 로고    scopus 로고
    • Osteoclasts: What do they do and how do they do it?
    • Teitelbaum SL. Osteoclasts: what do they do and how do they do it? Am J Pathol 2007;170:427-35.
    • (2007) Am J Pathol , vol.170 , pp. 427-435
    • Teitelbaum, S.L.1
  • 29
    • 4444235330 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinases and their inhibitors in peripheral synovitis and down-regulation by tumor necrosis factor α blockade in spondylarthropathy
    • Vandooren B, Kruithof E, Yu DT, Rihl M, Gu J, De Rycke L, et al. Involvement of matrix metalloproteinases and their inhibitors in peripheral synovitis and down-regulation by tumor necrosis factor α blockade in spondylarthropathy. Arthritis Rheum 2004;50:2942-53.
    • (2004) Arthritis Rheum , vol.50 , pp. 2942-2953
    • Vandooren, B.1    Kruithof, E.2    Yu, D.T.3    Rihl, M.4    Gu, J.5    De Rycke, L.6
  • 30
    • 27744515760 scopus 로고    scopus 로고
    • Involvement of subchondral bone marrow in rheumatoid arthritis: Lymphoid neogenesis and in situ relationship to subchondral bone marrow osteoclast recruitment
    • Bugatti S, Caporali R, Manzo A, Vitolo B, Pitzalis C, Montecucco C. Involvement of subchondral bone marrow in rheumatoid arthritis: lymphoid neogenesis and in situ relationship to subchondral bone marrow osteoclast recruitment. Arthritis Rheum 2005;52:3448-59.
    • (2005) Arthritis Rheum , vol.52 , pp. 3448-3459
    • Bugatti, S.1    Caporali, R.2    Manzo, A.3    Vitolo, B.4    Pitzalis, C.5    Montecucco, C.6
  • 31
    • 34247881945 scopus 로고    scopus 로고
    • Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation
    • Kim MW, Cho ML, Lee SH, Oh HJ, Kang CM, Ju JH, et al. Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation. Immunol Lett 2007;110:54-64.
    • (2007) Immunol Lett , vol.110 , pp. 54-64
    • Kim, M.W.1    Cho, M.L.2    Lee, S.H.3    Oh, H.J.4    Kang, C.M.5    Ju, J.H.6
  • 32
    • 21644448012 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor
    • Zannettino AC, Holding CA, Diamond P, Atkins GJ, Kostakis P, Farrugia A, et al. Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor. J Cell Physiol 2005;204:714-23.
    • (2005) J Cell Physiol , vol.204 , pp. 714-723
    • Zannettino, A.C.1    Holding, C.A.2    Diamond, P.3    Atkins, G.J.4    Kostakis, P.5    Farrugia, A.6
  • 33
    • 0033945112 scopus 로고    scopus 로고
    • Relationship between time-integrated C-reactive protein levels and radiologic progression in patients with rheumatoid arthritis
    • Plant MJ, Williams AL, O'Sullivan MM, Lewis PA, Coles EC, Jessop JD. Relationship between time-integrated C-reactive protein levels and radiologic progression in patients with rheumatoid arthritis. Arthritis Rheum 2000;43:1473-7.
    • (2000) Arthritis Rheum , vol.43 , pp. 1473-1477
    • Plant, M.J.1    Williams, A.L.2    O'Sullivan, M.M.3    Lewis, P.A.4    Coles, E.C.5    Jessop, J.D.6
  • 34
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis
    • for the Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
    • Lipsky PE, van der Heijde DM, St Clair EW, Furst DE, Breedveld FC, Kalden JR, et al, for the Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. Infliximab and methotrexate in the treatment of rheumatoid arthritis. N Engl J Med 2000;343:1594-602.
    • (2000) N Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    van der Heijde, D.M.2    St Clair, E.W.3    Furst, D.E.4    Breedveld, F.C.5    Kalden, J.R.6
  • 35
    • 0034523328 scopus 로고    scopus 로고
    • TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
    • Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL. TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Inves 2000;106:1481-8.
    • (2000) J Clin Inves , vol.106 , pp. 1481-1488
    • Lam, J.1    Takeshita, S.2    Barker, J.E.3    Kanagawa, O.4    Ross, F.P.5    Teitelbaum, S.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.