Caffeine mediates sustained inactivation of breast cancer-associated myofibroblasts via up-regulation of tumor suppressor genes

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Al Ansari, Mysoon M ^a   Aboussekhra, Abdelilah ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CAFFEINE; CAVEOLIN 1; GELATINASE A; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P16; PROTEIN P21; PROTEIN P53; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN A;

ARTICLE; BREAST CANCER; BREAST STROMAL FIBROBLAST; CANCER ASSOCIATED FIBROBLAST; CANCER CELL; CELL INVASION; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MIGRATION INHIBITION; MYOFIBROBLAST; PARACRINE SIGNALING; TUMOR SUPPRESSOR GENE; UPREGULATION;

BREAST NEOPLASMS; CAFFEINE; CAVEOLIN 1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOKINES; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOBLOTTING; MYOFIBROBLASTS; NEOPLASM PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84896996277     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090907     Document Type: Article

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