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Volumn 70, Issue 7, 2010, Pages 2655-2664

Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ESTRADIOL; ESTROGEN RECEPTOR; RECOMBINANT VASCULOTROPIN; SEPRASE; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN; VIMENTIN;

EID: 77950845143     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4373     Document Type: Article
Times cited : (46)

References (51)
  • 1
    • 0029036480 scopus 로고
    • Hormones and mammary carcinogenesis in mice, rats, and humans: A unifying hypothesis
    • Nandi S, Guzman RC, Yang J. Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis. Proc Natl Acad Sci U S A 1995;92:3650-3657
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3650-3657
    • Nandi, S.1    Guzman, R.C.2    Yang, J.3
  • 2
    • 0032034512 scopus 로고    scopus 로고
    • The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland
    • Woodward TL, Xie JW, Haslam SZ. The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland. J Mammary Gland Biol Neoplasia 1998;3: 117-131
    • (1998) J Mammary Gland Biol Neoplasia , vol.3 , pp. 117-131
    • Woodward, T.L.1    Xie, J.W.2    Haslam, S.Z.3
  • 4
    • 2342444724 scopus 로고    scopus 로고
    • Watch thy neighbor: Cancer is a communal affair
    • DOI 10.1242/jcs.01137
    • Weaver VM, Gilbert P. Watch thy neighbor: cancer is a communal affair. J Cell Sci 2004;117:1287-1290 (Pubitemid 38559806)
    • (2004) Journal of Cell Science , vol.117 , Issue.8 , pp. 1287-1290
    • Weaver, V.M.1    Gilbert, P.2
  • 5
    • 72549085332 scopus 로고    scopus 로고
    • Activation of host wound responses in breast cancer microenvironment
    • Troester MA, Lee MH, Carter M, et al. Activation of host wound responses in breast cancer microenvironment. Clin Cancer Res 2009; 15:7020-7028
    • (2009) Clin Cancer Res , vol.15 , pp. 7020-7028
    • Troester, Ma.1    Lee, M.H.2    Carter, M.3
  • 6
    • 0035170731 scopus 로고    scopus 로고
    • Reactive stroma in prostate cancer progression
    • Tuxhorn JA, Ayala GE, Rowley DR. Reactive stroma in prostate cancer progression. J Urol 2001;166:2472-2483 (Pubitemid 33065339)
    • (2001) Journal of Urology , vol.166 , Issue.6 , pp. 2472-2483
    • Tuxhorn, J.A.1    Ayala, G.E.2    Rowley, D.R.3
  • 7
    • 0035032263 scopus 로고    scopus 로고
    • The complexities of breast cancer desmoplasia
    • Walker RA. The complexities of breast cancer desmoplasia. Breast Cancer Res 2001;3:143-145
    • (2001) Breast Cancer Res , vol.3 , pp. 143-145
    • Walker, R.A.1
  • 8
    • 34648852355 scopus 로고    scopus 로고
    • Pancreatic cancer-associated stroma production
    • Korc M. Pancreatic cancer-associated stroma production. Am J Surg 2007;194:S84-6.
    • (2007) Am J Surg , vol.194
    • Korc, M.1
  • 9
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121:335-348 (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 11
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 12
    • 0032933778 scopus 로고    scopus 로고
    • Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast
    • Brown LF, Guidi AJ, Schnitt SJ, et al. Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. Clin Cancer Res 1999;5:1041-1056
    • (1999) Clin Cancer Res , vol.5 , pp. 1041-1056
    • Brown, L.F.1    Guidi, A.J.2    Schnitt, S.J.3
  • 13
    • 0037115522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4
    • Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 2002; 62:7203-7206
    • (2002) Cancer Res , vol.62 , pp. 7203-7206
    • Bachelder, R.E.1    Wendt, Ma.2    Mercurio, A.M.3
  • 14
    • 33748087454 scopus 로고    scopus 로고
    • Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium
    • DOI 10.1158/0008-5472.CAN-06-1456
    • Jacobsen BM, Harrell JC, Jedlicka P, Borges VF, Varella-Garcia M, Horwitz KB. Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium. Cancer Res 2006;66:8274-8279 (Pubitemid 44299197)
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 8274-8279
    • Jacobsen, B.M.1    Harrell, J.C.2    Jedlicka, P.3    Borges, V.F.4    Varella-Garcia, M.5    Horwitz, K.B.6
  • 16
    • 33749457974 scopus 로고    scopus 로고
    • Estrogen receptor positive breast cancer metastasis: Altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes
    • Harrell JC, Dye WW, Allred DC, et al. Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Res 2006;66:9308-9315
    • (2006) Cancer Res , vol.66 , pp. 9308-9315
    • Harrell, J.C.1    Dye, W.W.2    Allred, D.C.3
  • 17
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • DOI 10.1016/S1046-2023(03)00032-X
    • Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in threedimensional basement membrane cultures. Methods 2003;30: 256-268 (Pubitemid 36677560)
    • (2003) Methods , vol.30 , Issue.3 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 19
    • 48349094384 scopus 로고    scopus 로고
    • Unraveling the microenvironmental influences on the normal mammary gland and breast cancer
    • Weigelt B, Bissell MJ. Unraveling the microenvironmental influences on the normal mammary gland and breast cancer. Semin Cancer Biol 2008;18:311-321
    • (2008) Semin Cancer Biol , vol.18 , pp. 311-321
    • Weigelt, B.1    Bissell, M.J.2
  • 20
    • 34247398806 scopus 로고    scopus 로고
    • Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
    • DOI 10.1242/dev.02797
    • Moraes RC, Zhang X, Harrington N, et al. Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia. Development 2007;134:1231-1242 (Pubitemid 46630090)
    • (2007) Development , vol.134 , Issue.6 , pp. 1231-1242
    • Moraes, R.C.1    Zhang, X.2    Harrington, N.3    Fung, J.Y.4    Wu, M.-F.5    Hilsenbeck, S.G.6    Allred, D.C.7    Lewis, M.T.8
  • 21
    • 0032835899 scopus 로고    scopus 로고
    • Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1- MMP in primary breast carcinomas
    • DOI 10.1002/(SICI)1096-9896(199910)189:2<161::AID-PATH406>3.0.CO;2- 2
    • Jones JL, Glynn P, Walker RA. Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas. J Pathol 1999;189:161-168 (Pubitemid 29448907)
    • (1999) Journal of Pathology , vol.189 , Issue.2 , pp. 161-168
    • Jones, J.L.1    Glynn, P.2    Walker, R.A.3
  • 22
    • 0043136697 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor by MCF-7 breast cancer cells promotes estrogen-independent tumor growth in vivo
    • Guo P, Fang Q, Tao HQ, et al. Overexpression of vascular endothelial growth factor by MCF-7 breast cancer cells promotes estrogen-independent tumor growth in vivo. Cancer Res 2003; 63:4684-4691 (Pubitemid 36951048)
    • (2003) Cancer Research , vol.63 , Issue.15 , pp. 4684-4691
    • Guo, P.1    Fang, Q.2    Tao, H.-Q.3    Schafer, C.A.4    Fenton, B.M.5    Ding, I.6    Hu, B.7    Cheng, S.-Y.8
  • 23
    • 0242710183 scopus 로고    scopus 로고
    • Update on animal models developed for analyses of estrogen receptor biological activity
    • Korach KS, Emmen JM, Walker VR, et al. Update on animal models developed for analyses of estrogen receptor biological activity. J Steroid Biochem Mol Biol 2003;86:387-391
    • (2003) J Steroid Biochem Mol Biol , vol.86 , pp. 387-391
    • Korach, K.S.1    Emmen, J.M.2    Walker, V.R.3
  • 24
    • 20544455330 scopus 로고    scopus 로고
    • Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
    • DOI 10.1016/j.bbrc.2005.05.132, PII S0006291X05011344
    • Ferrara N, Hillan KJ, Novotny W. Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy. Biochem Biophys Res Commun 2005;333:328-335 (Pubitemid 40848295)
    • (2005) Biochemical and Biophysical Research Communications , vol.333 , Issue.2 , pp. 328-335
    • Ferrara, N.1    Hillan, K.J.2    Novotny, W.3
  • 26
    • 0037842715 scopus 로고    scopus 로고
    • Vascular endothelial growth factorand anti-angiogenic peptides as therapeutic and investigational molecules
    • Zachary I. Vascular endothelial growth factor and anti-angiogenic peptides as therapeutic and investigational molecules. IDrugs 2003;6:224-231 (Pubitemid 36717189)
    • (2003) IDrugs , vol.6 , Issue.3 , pp. 224-231
    • Zachary, I.1
  • 27
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • Lee TH, Seng S, Sekine M, et al. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 2007;4:e186.
    • (2007) PLoS Med , vol.4
    • Lee, T.H.1    Seng, S.2    Sekine, M.3
  • 28
    • 13244262659 scopus 로고    scopus 로고
    • Antigen binding of human IgG fabs mediate ERK-associated proliferation of human breast cancer cells
    • DOI 10.1089/dna.2005.24.73
    • Wen YJ, Mancino A, Pashov A, Whitehead T, Stanley J, KieberEmmons T. Antigen binding of human IgG Fabs mediate ERKassociated proliferation of human breast cancer cells. DNA Cell Biol 2005;24:73-84. (Pubitemid 40189744)
    • (2005) DNA and Cell Biology , vol.24 , Issue.2 , pp. 73-84
    • Wen, Y.-J.1    Mancino, A.2    Pashov, A.3    Whitehead, T.4    Stanley, J.5    Kieber-Emmons, T.6
  • 30
    • 33947230755 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines
    • DOI 10.1158/1541-7786.MCR-06-0263
    • Hollestelle A, Elstrodt F, Nagel JH, Kallemeijn WW, Schutte M. Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines. Mol Cancer Res 2007;5:195-201. (Pubitemid 46424000)
    • (2007) Molecular Cancer Research , vol.5 , Issue.2 , pp. 195-201
    • Hollestelle, A.1    Elstrodt, F.2    Nagel, J.H.A.3    Kallemeijn, W.W.4    Schutte, M.5
  • 31
    • 0027161705 scopus 로고
    • Induction of α-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts
    • Ronnov-Jessen L, Petersen OW. Induction of a-smooth muscle actin by transforming growth factor-β 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia. Lab Invest 1993;68:696-707. (Pubitemid 23202798)
    • (1993) Laboratory Investigation , vol.68 , Issue.6 , pp. 696-707
    • Ronnov-Jessen, L.1    Petersen, O.W.2
  • 32
    • 33845707705 scopus 로고    scopus 로고
    • VEGF and PIGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization
    • Li B, Sharpe EE, Maupin AB, et al. VEGF and PIGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization. FASEB J 2006;20: 1495-1497
    • (2006) FASEB J , vol.20 , pp. 1495-1497
    • Li, B.1    Sharpe, E.E.2    Maupin, A.B.3
  • 34
    • 0037052448 scopus 로고    scopus 로고
    • Stromal effects on mammary gland development and breast cancer
    • Wiseman BS, Werb Z. Stromal effects on mammary gland development and breast cancer. Science 2002;296:1046-1049
    • (2002) Science , vol.296 , pp. 1046-1049
    • Wiseman, B.S.1    Werb, Z.2
  • 35
    • 0015852146 scopus 로고
    • Breast cancer: Induction of differentiation by embryonic tissue
    • DeCosse JJ, Gossens CL, Kuzma JF, Unsworth BR. Breast cancer: induction of differentiation by embryonic tissue. Science 1973;181: 1057-1058
    • (1973) Science , vol.181 , pp. 1057-1058
    • Decosse, J.J.1    Gossens, C.L.2    Kuzma, J.F.3    Unsworth, B.R.4
  • 36
    • 0017756381 scopus 로고
    • Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth
    • Cooper M, Pinkus H. Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth. Cancer Res 1977;37:2544-2552
    • (1977) Cancer Res , vol.37 , pp. 2544-2552
    • Cooper, M.1    Pinkus, H.2
  • 38
    • 0035253742 scopus 로고    scopus 로고
    • Know thy neighbor: Stromal cells can contribute oncogenic signals
    • Tlsty TD, Hein PW. Know thy neighbor: stromal cells can contribute oncogenic signals. Curr Opin Genet Dev 2001;11:54-59
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 54-59
    • Tlsty, T.D.1    Hein, P.W.2
  • 40
    • 0034161922 scopus 로고    scopus 로고
    • Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
    • Barcellos-Hoff MH, Ravani SA. Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res 2000;60:1254-1260
    • (2000) Cancer Res , vol.60 , pp. 1254-1260
    • Barcellos-Hoff, M.H.1    Ravani, S.A.2
  • 41
    • 3042667195 scopus 로고    scopus 로고
    • Three-dimensional in vitro tissue culture models of breast cancer-a review
    • Kim JB, Stein R, O'Hare MJ. Three-dimensional in vitro tissue culture models of breast cancer-a review. Breast Cancer Res Treat 2004; 85:281-291
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 281-291
    • Kim, J.B.1    Stein, R.2    O'Hare, M.J.3
  • 42
    • 0039827497 scopus 로고
    • Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells
    • DOI 10.1073/pnas.84.1.136
    • Li ML, Aggeler J, Farson DA, Hatier C, Hassell J, Bissell MJ. Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proc Natl Acad Sci U S A 1987;84:136-140 (Pubitemid 17013590)
    • (1987) Proceedings of the National Academy of Sciences of the United States of America , vol.84 , Issue.1 , pp. 136-140
    • Li, M.L.1    Aggeler, J.2    Farson, D.A.3
  • 43
    • 0035872250 scopus 로고    scopus 로고
    • A heterologous 3-D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation
    • DOI 10.1006/excr.2001.5210
    • Kunz-Schughart LA, Heyder P, Schroeder J, Knuechel R. A heterologous 3-D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation. Exp Cell Res 2001 ; 266:74-86. (Pubitemid 32989044)
    • (2001) Experimental Cell Research , vol.266 , Issue.1 , pp. 74-86
    • Kunz-Schughart, L.A.1    Heyder, P.2    Schroeder, J.3    Knuechel, R.4
  • 44
    • 0037484174 scopus 로고    scopus 로고
    • Modeling tissue-specific signaling and organ function in three dimensions
    • Schmeichel KL, Bissell MJ. Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci 2003;116: 2377-2388
    • (2003) J Cell Sci , vol.116 , pp. 2377-2388
    • Schmeichel, K.L.1    Bissell, M.J.2
  • 45
    • 65449159747 scopus 로고    scopus 로고
    • A compact VEGF signature associated with distant metastases and poor outcomes
    • Hu Z, Fan C, Livasy C, et al. A compact VEGF signature associated with distant metastases and poor outcomes. BMC Med 2009;7:9.
    • (2009) BMC Med , vol.7 , pp. 9
    • Hu, Z.1    Fan, C.2    Livasy, C.3
  • 46
    • 34547451080 scopus 로고    scopus 로고
    • Human bone marrow stromal cells enhance breast cancer cell growth rates in a cell line-dependent manner when evaluated in 3D tumor environments
    • Sasser AK, Mundy BL, Smith KM, et al. Human bone marrow stromal cells enhance breast cancer cell growth rates in a cell line-dependent manner when evaluated in 3D tumor environments. Cancer Lett 2007;254:255-264
    • (2007) Cancer Lett , vol.254 , pp. 255-264
    • Sasser, A.K.1    Mundy, B.L.2    Smith, K.M.3
  • 47
    • 0025367297 scopus 로고
    • Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
    • Bartek J, Iggo R, Gannon J, Lane DP. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene 1990;5:893-899 (Pubitemid 20192074)
    • (1990) Oncogene , vol.5 , Issue.6 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 48
    • 0037277319 scopus 로고    scopus 로고
    • Breast cancer-induced angiogenesis: Multiple mechanisms and the role of the microenvironment
    • DOI 10.1186/bcr589
    • Boudreau N, Myers C. Breast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironment. Breast Cancer Res 2003;5:140-146 (Pubitemid 36519407)
    • (2003) Breast Cancer Research , vol.5 , Issue.3 , pp. 140-146
    • Boudreau, N.1    Myers, C.2
  • 49
    • 42549173671 scopus 로고    scopus 로고
    • The potential of anti-vascular endothelial growth factor therapy in metastatic breast cancer: Clinical experience with anti-angiogenic agents, focusing on bevacizumab
    • Marty M, Pivot X. The potential of anti-vascular endothelial growth factor therapy in metastatic breast cancer: clinical experience with anti-angiogenic agents, focusing on bevacizumab. Eur J Cancer 2008;44:912-920
    • (2008) Eur J Cancer , vol.44 , pp. 912-920
    • Marty, M.1    Pivot, X.2
  • 51
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357:2666-2676
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3


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