Splenic stromal cells from aged mice produce higher levels of IL-6 compared to young mice

Mediators of Inflammation

Volumn 2014, Issue , 2014, Pages

  Park, Jihyun ^a   Miyakawa, Takuya ^a   Shiokawa, Aya ^a   Nakajima Adachi, Haruyo ^a   Tanokura, Masaru ^a   Hachimura, Satoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; IL17A PROTEIN, MOUSE; INTERLEUKIN 17; INTERLEUKIN-6, MOUSE; PTPRC PROTEIN, MOUSE;

ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL ISOLATION; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; STROMA CELL; AGING; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CHEMISTRY; CYTOLOGY; METABOLISM; SPLEEN;

AGING; ANIMALS; ANTIGENS, CD45; FEMALE; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RNA, MESSENGER; SPLEEN; STROMAL CELLS;

EID: 84896934419     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/826987     Document Type: Article

References (39)

1. Mammucari C., Rizzuto R., Signaling pathways in mitochondrial dysfunction and aging. Mechanisms of Ageing and Development 2010 131 7-8 536 543 2-s2.0-77956189388 10.1016/j.mad.2010.07.003
2. Gruver A. L., Hudson L. L., Sempowski G. D., Immunosenescence of ageing. Journal of Pathology 2007 211 2 144 156 2-s2.0-33846656968 10.1002/path.2104 (Pubitemid 46195513)
3. Starr M. E., Evers B. M., Saito H., Age-associated increase in cytokine production during systemic inflammation: adipose tissue as a major source of IL-6. Journals of Gerontology A 2009 64 7 723 730 2-s2.0-67649653963 10.1093/gerona/glp046
4. Maggio M., Guralnik J. M., Longo D. L., Ferrucci L., Interleukin-6 in aging and chronic disease: a magnificent pathway. Journals of Gerontology 2006 61 6 575 584 2-s2.0-33745185337
5. Sarkar D., Fisher P. B., Molecular mechanisms of aging-associated inflammation. Cancer Letters 2006 236 1 13 23 2-s2.0-33745384267 10.1016/j.canlet.2005.04.009 (Pubitemid 44382538)
6. Franceschi C., Bonafè M., Valensin S., Olivieri F., De Luca M., Ottaviani E., De Benedictis G., Inflamm-aging. An evolutionary perspective on immunosenescence. Annals of the New York Academy of Sciences 2000 908 244 254 2-s2.0-0033911488 (Pubitemid 30462008)
7. Kovacs E. J., Gomez C. R., Karavitis J., Palmer J. L., Faunce D. E., Ramirez L., Nomellini V., Interleukin-6 contributes to age-related alteration of cytokine production by macrophages. Mediators of Inflammation 2010 2010 7 2-s2.0-77955361681 10.1155/2010/475139 475139
8. Pawelec G., Human immunosenescence: is it infectious? Immunological Reviews 2005 205 257 268 (Pubitemid 40780191)
9. Kovacs E. J., Palmer J. L., Fortin C. F., Fülöp T. Jr., Goldstein D. R., Linton P.-J., Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors. Trends in Immunology 2009 30 7 319 324 2-s2.0-67649610923 10.1016/j.it.2009.03.012
10. Busse P. J., Mathur S. K., Age-related changes in immune function: effect on airway inflammation. Journal of Allergy and Clinical Immunology 2010 126 4 690 699 2-s2.0-77957823632 10.1016/j.jaci.2010.08.011
11. Cardona V., Guilarte M., Luengo O., Labrador-Horrillo M., Sala-Cunil A., Garriga T., Allergic diseases in the elderly. Clinical and Translational Allergy 2011 1, article 11
12. Omoigui S., The Interleukin-6 inflammation pathway from cholesterol to aging-role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. Immunity and Ageing 2007 4, article 1 2-s2.0-34047193690 10.1186/1742-4933-4-1 (Pubitemid 46534042)
13. Naugler W. E., Karin M., The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends in Molecular Medicine 2008 14 3 109 119 2-s2.0-40649109728 10.1016/j.molmed.2007.12.007
14. Huang H., Patel D. D., Manton K. G., The immune system in aging: roles of cytokines, T cells and NK cells. Frontiers in Bioscience 2005 10 192 215 2-s2.0-23044439649
15. Salminen A., Huuskonen J., Ojala J., Kauppinen A., Kaarniranta K., Suuronen T., Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Research Reviews 2008 7 2 83 105 2-s2.0-40949123149 10.1016/j.arr.2007.09.002 (Pubitemid 351418294)
16. Ershler W. B., Keller E. T., Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annual Review of Medicine 2000 51 245 270 2-s2.0-0034051068 10.1146/annurev.med.51.1.245 (Pubitemid 30216036)
17. Kiecolt-Glaser J. K., Preacher K. J., MacCallum R. C., Atkinson C., Malarkey W. B., Glaser R., Chronic stress and age-related increases in the proinflammatory cytokine IL-6. Proceedings of the National Academy of Sciences of the United States of America 2003 100 15 9090 9095 2-s2.0-0041305837 10.1073/pnas.1531903100 (Pubitemid 36899228)
18. Wellen K. E., Hotamisligil G. S., Inflammation, stress, and diabetes. Journal of Clinical Investigation 2005 115 5 1111 1119 2-s2.0-18244370762 10.1172/JCI200525102 (Pubitemid 40629025)
19. Ogura H., Murakami M., Okuyama Y., Tsuruoka M., Kitabayashi C., Kanamoto M., Nishihara M., Iwakura Y., Hirano T., Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction. Immunity 2008 29 4 628 636 2-s2.0-55049118394 10.1016/j.immuni.2008.07.018
20. Cyster J. G., Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annual Review of Immunology 2005 23 127 159 2-s2.0-17644365138 10.1146/annurev.immunol.23.021704.115628 (Pubitemid 40563167)
21. Roozendaal R., Mebius R. E., Stromal cell-immune cell interactions. Annual Review of Immunology 2011 29 23 43 2-s2.0-79953035119 10.1146/annurev-immunol-031210-101357
22. Link A., Vogt T. K., Favre S., Britschgi M. R., Acha-Orbea H., Hinz B., Cyster J. G., Luther S. A., Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nature Immunology 2007 8 11 1255 1265 2-s2.0-35548975191 10.1038/ni1513 (Pubitemid 350011765)
23. den Haan J. M., Mebius R. E., Kraal G., Stromal cells of the mouse spleen. Frontiers in Immunology 2012 3 1 5
24. Boehmer E. D., Goral J., Faunce D. E., Kovacs E. J., Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression. Journal of Leukocyte Biology 2004 75 2 342 349 2-s2.0-0842309938 10.1189/jlb.0803389 (Pubitemid 38174592)
25. Shortman K., Naik S. H., Steady-state and inflammatory dendritic-cell development. Nature Reviews Immunology 2007 7 1 19 30 2-s2.0-33845898737 10.1038/nri1996 (Pubitemid 46020824)
26. Saito H., Patterson C., Hu Z., Runge M. S., Tipnis U., Sinha M., Papaconstantinou J., Expression and self-regulatory function of cardiac interleukin-6 during endotoxemia. American Journal of Physiology: Heart and Circulatory Physiology 2000 279 5 H2241 H2248 2-s2.0-0033674089
27. O'Shea J. J., Ma A., Lipsky P., Cytokines and autoimmunity. Nature Reviews Immunology 2002 2 1 37 45 2-s2.0-0036359580 (Pubitemid 37328774)
28. Latifi S. Q., O'Riordan M. A., Levine A. D., Stallion A., Persistent elevation of serum interleukin-6 in intraabdominal sepsis identifies those with prolonged length of stay. Journal of Pediatric Surgery 2004 39 10 1548 1552 2-s2.0-5344277490 10.1016/j.jpedsurg.2004.06.015 (Pubitemid 39349740)
29. Ishihara K., Hirano T., IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine and Growth Factor Reviews 2002 13 4-5 357 368 2-s2.0-0036694589 10.1016/S1359-6101(02)00027-8
30. Murakami M., Okuyama Y., Ogura H., Asano S., Arima Y., Tsuruoka M., Harada M., Kanamoto M., Sawa Y., Iwakura Y., Takatsu K., Kamimura D., Hirano T., Local microbleeding facilitates IL-6-and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells. Journal of Experimental Medicine 2011 208 1 103 114 2-s2.0-78651474359 10.1084/jem.20100900
31. Komatsu N., Takayanagi H., Inflammation and bone destruction in arthritis: synergistic activity of immune and mesenchymal cells in joints. Frontiers in Immunology 2012 3 1 11
32. Kumagai N., Chiba Y., Hosono M., Fujii M., Kawamura N., Keino H., Yoshikawa K., Ishii S., Saitoh Y., Satoh M., Shimada A., Hosokawa M., Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse. Brain Research 2007 1185 1 75 85 2-s2.0-36448941228 10.1016/j.brainres.2007.09.021 (Pubitemid 350166311)
33. Meador B. M., Krzyszton C. P., Johnson R. W., Huey K. A., Effects of IL-10 and age on IL-6, IL-1 β and TNF- responses in mouse skeletal and cardiac muscle to an acute inflammatory insult. Journal of Applied Physiology 2008 104 4 991 997 2-s2.0-41949108771 10.1152/japplphysiol.01079.2007 (Pubitemid 351507936)
34. Gomez C. R., Goral J., Ramirez L., Kopf M., Kovacs E. J., Aberrant acute-phase response in aged interleukin-6 knockout mice. Shock 2006 25 6 581 585 2-s2.0-33745607015 10.1097/01.shk.000029553.39081.ec (Pubitemid 44297018)
35. Gajanant S., Bacterial infections and the pathogenesis of autoimmune conditions. British Journal of Medical Practitioners 2009 2 6 13
36. Tanaka K., Kishimoto T., Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases. International Journal of Biological Sciences 2012 8 1227 1236
37. Wolf J., Weinberger B., Arnold C. R., Maier A. B., Westendorp R. G., Grubeck-Loebenstein B., The effect of chronological age on the inflammatory response of human fibroblasts. Experimental Gerontology 2012 47 749 753
38. Katz Y., Nadiv O., Beer Y., Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1, 6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes. Arthritis Rheumatism 2001 44 2176 2184 (Pubitemid 33644063)
39. Hartupee J., Liu C., Novotny M., Li X., Hamilton T., IL-17 enhances chemokine gene expression through mRNA stabilization. Journal of Immunology 2007 179 6 4135 4141 2-s2.0-35748973565