Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 4, 2014, Pages 2186-2201

  Chowdhury, Sayan ^a   Mukherjee, Tulika ^a   Chowdhury, Somenath Roy ^a   Sengupta, Souvik ^b   Mukhopadhyay, Sibabrata ^a   Jaisankar, Parasuraman ^a   Majumder, Hemanta K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b DEPARTMENT OF MATERIALS SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3 O,28 O DISUCCINYL BETULIN; BETULIN; CASPASE; CYTOCHROME C; ENDONUCLEASE G; LIPOCORTIN 5; METACASPASE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DNA DAMAGE; DNA DEGRADATION; DNA FRAGMENTATION; ENZYME ACTIVATION; G1 PHASE CELL CYCLE CHECKPOINT; LEISHMANIA DONOVANI; LIPID PEROXIDATION; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMASTIGOTE;

ANTIPROTOZOAL AGENTS; DNA FRAGMENTATION; ENDODEOXYRIBONUCLEASES; LEISHMANIA DONOVANI; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; TRITERPENES;

EID: 84896920458     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02193-13     Document Type: Article

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