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Volumn 277, Issue 27, 2002, Pages 24717-24727
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Increase in cytosolic Ca2+ levels through the activation of non-selective cation channels induced by oxidative stress causes mitochondrial depolarization leading to apoptosis-like death in Leishmania donovani promastigotes
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTIOXIDANTS;
CELL MEMBRANES;
CHELATION;
CHEMICAL ACTIVATION;
OXIDATION;
STRESSES;
MITOCHONDRIAL MEMBRANES;
BIOCHEMISTRY;
ACETYLCYSTEINE;
ADENOSINE TRIPHOSPHATE;
ANTIOXIDANT;
CALCIUM ION;
CARDIOLIPIN;
CATION CHANNEL;
FLUFENAMIC ACID;
GLUTATHIONE;
HYDROGEN PEROXIDE;
REACTIVE OXYGEN METABOLITE;
SODIUM ION;
THIOL DERIVATIVE;
1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER;
1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER;
CATION;
DRUG DERIVATIVE;
EGTAZIC ACID;
ION CHANNEL;
POTASSIUM;
RUTHENIUM RED;
SODIUM;
VERAPAMIL;
APOPTOSIS;
ARTICLE;
CALCIUM CELL LEVEL;
CALCIUM HOMEOSTASIS;
CONTROLLED STUDY;
CYTOSOL;
EXTRACELLULAR CALCIUM;
LEISHMANIA DONOVANI;
LEISHMANIASIS;
MEMBRANE DEPOLARIZATION;
MEMBRANE POTENTIAL;
MITOCHONDRIAL MEMBRANE;
NONHUMAN;
OXIDATIVE STRESS;
PRIORITY JOURNAL;
PROMASTIGOTE;
SIGNAL TRANSDUCTION;
ANIMAL;
CELL DEATH;
CYTOLOGY;
DRUG EFFECT;
METABOLISM;
MITOCHONDRION;
PHYSIOLOGY;
LEISHMANIA DONOVANI;
NASO HEXACANTHUS;
ACETYLCYSTEINE;
ADENOSINE TRIPHOSPHATE;
ANIMALS;
APOPTOSIS;
CATIONS;
CELL DEATH;
CYTOSOL;
EGTAZIC ACID;
GLUTATHIONE;
HYDROGEN PEROXIDE;
ION CHANNELS;
LEISHMANIA DONOVANI;
MITOCHONDRIA;
OXIDATIVE STRESS;
POTASSIUM;
REACTIVE OXYGEN SPECIES;
RUTHENIUM RED;
SODIUM;
VERAPAMIL;
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EID: 0037024695
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M201961200 Document Type: Article |
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Times cited : (188)
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References (59)
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