Bovine lactoferrin binds oleic acid to form an anti-tumor complex similar to HAMLET

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1841, Issue 4, 2014, Pages 535-543

  Fang, Bing ^a,b   Zhang, Ming ^c   Tian, Mai ^a,d   Jiang, Lu ^a   Guo, Hui Yuan ^e   Ren, Fa Zheng ^a,d,e  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b ACADEMY OF STATE ADMINISTRATION OF GRAIN   (China)

^c BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY   (China)

^d Beijing Laboratory of Food Quality and Safety   (China)

^e Beijing Higher Institution Engineering Research Center of Animal Product   (China)

Author keywords

Anti tumor; Apoptosis; HAMLET; Isothermal titration calorimetry; Lactoferrin; Oleic acid

Indexed keywords

ALPHA LACTALBUMIN; DEATH RECEPTOR; LACTOFERRIN; METHYLENE BLUE; OLEIC ACID; TRYPTOPHAN; HAMLET COMPLEX, HUMAN; LACTALBUMIN;

ALPHA HELIX; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BETA SHEET; BETA TURN; CATTLE; CELL STRAIN HEPG2; CELL STRAIN HT29; CELL STRAIN MCF 7; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG BINDING SITE; DRUG STRUCTURE; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HEAT TREATMENT; HUMAN; HUMAN CELL; HYDROGEN BOND; ISOTHERMAL TITRATION CALORIMETRY; LD 50; MITOCHONDRION; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LIPID INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TUMOR CELL; WESTERN BLOTTING; ANIMAL; BOVINAE; CHEMISTRY; DRUG EFFECTS; HEPG2 CELL LINE; ISOLATION AND PURIFICATION; NEOPLASMS; PATHOLOGY;

ANIMALS; APOPTOSIS; CATTLE; CIRCULAR DICHROISM; FLOW CYTOMETRY; HEP G2 CELLS; HUMANS; HYDROGEN BONDING; LACTALBUMIN; LACTOFERRIN; NEOPLASMS; OLEIC ACID; OLEIC ACIDS; PROTEIN STRUCTURE, SECONDARY;

EID: 84896892583     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.12.008     Document Type: Article

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