The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity

Journal of Experimental Medicine

Volumn 211, Issue 3, 2014, Pages 427-440

  Medgyesi, David ^a,b   Hobeika, Elias ^a,b   Biesen, Robert ^c   Kollert, Florian ^d   Taddeo, Adriano ^e   Voll, Reinhard E ^d   Hiepe, Falk ^c   Reth, Michael ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

^e POTSDAM INSTITUTE FOR CLIMATE IMPACT RESEARCH PIK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR RECEPTOR; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CD40 ANTIGEN; CD40 LIGAND; HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 4; LEUKOSIALIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE 1B; RITUXIMAB; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL ISOLATION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENOTYPE; GERMINAL CENTER; HUMAN; IMMUNOGLOBULIN DEPOSITION; IMMUNOLOGICAL TOLERANCE; MALE; MIDDLE AGED; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SPLEEN; SURVIVAL RATE; VERY ELDERLY; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD40; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; AUTOIMMUNITY; B-CELL ACTIVATION FACTOR RECEPTOR; B-LYMPHOCYTES; BLOTTING, WESTERN; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MIDDLE AGED; PLASMIDS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84896882731     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131196     Document Type: Article

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