Inhibition of airway epithelial-to-mesenchymal transition and fibrosis by kaempferol in endotoxin-induced epithelial cells and ovalbumin-sensitized mice

Laboratory Investigation

Volumn 94, Issue 3, 2014, Pages 297-308

  Gong, Ju Hyun ^a   Cho, In Hee ^a   Shin, Daekeun ^a   Han, Seon Young ^a   Park, Sin Hye ^a   Kang, Young Hee ^a  

^a Hallym University   (South Korea)

Author keywords

airway fibrosis; epithelial to mesenchymal transition; kaempferol; protease activated receptor 1; transforming growth factor

Indexed keywords

1 AMINO 3 CYCLOPROPYLAMINO 7 (4 ISOPROPYLBENZYL) 7H PYRROLO[3,2 F]QUINAZOLINE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN FIBER; COLLAGEN TYPE 4; ENDOTOXIN; GELATINASE A; KAEMPFEROL; LIPOPOLYSACCHARIDE; MATRIX METALLOPROTEINASE 14; NERVE CELL ADHESION MOLECULE; OVALBUMIN; PROTEINASE ACTIVATED RECEPTOR 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG FIBROSIS; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION;

ANIMALS; ASTHMA; BRONCHI; CELL LINE; COLLAGEN TYPE IV; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; KAEMPFEROLS; LIPOPOLYSACCHARIDES; MALE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED BALB C; OVALBUMIN; PULMONARY FIBROSIS; RECEPTOR, PAR-1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84896881833     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.137     Document Type: Article

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