Protease-activated receptors (PAR)-1 and -3 drive epithelialmesenchymal transition of alveolar epithelial cells - Potential role in lung fibrosis

Thrombosis and Haemostasis

Volumn 110, Issue 2, 2013, Pages 295-307

  Wygrecka, Malgorzata ^a   Didiasova, Miroslava ^a   Berscheid, Sebastian ^a   Piskulak, Katarzyna ^b   Taborski, Brigitte ^a   Zakrzewicz, Dariusz ^a   Kwapiszewska, Grazyna ^c   Preissner, Klaus T ^a   Markart, Philipp ^b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^c LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

Coagulation proteases; Epithelial mesenchymal transition; Protease activated receptors; Pulmonary fibrosis; Thrombin

Indexed keywords

BLEOMYCIN; CYTOKERATIN 19; FIBRONECTIN; GELATINASE A; GELATINASE B; OCCLUDIN; PROTEIN ZO1; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; PROTHROMBIN; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FIBROSING ALVEOLITIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; LUNG FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLEOMYCIN; CELL DIFFERENTIATION; CELL LINE; DISEASE MODELS, ANIMAL; EPITHELIAL-MESENCHYMAL TRANSITION; GENE KNOCKDOWN TECHNIQUES; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MICE; MYOFIBROBLASTS; PNEUMOCYTES; PROTHROMBIN; PULMONARY FIBROSIS; RECEPTOR, PAR-1; RECEPTORS, PROTEINASE-ACTIVATED; RECEPTORS, THROMBIN; RNA, MESSENGER; THROMBIN;

EID: 84880802594     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH12-11-0854     Document Type: Article

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