Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 8, 2014, Pages 2954-2959

  Lee, Young Sam ^a,b   Gregory, Mark T ^a   Yang, Wei ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b SAMSUNG Electronics   (South Korea)

Author keywords

MAD2L2; Processivity; REV3L; TLS; Two polymerase lesion bypass

Indexed keywords

ASPARAGINE; ASPARTIC ACID; CISPLATIN; DNA POLYMERASE; GUANINE; MALTOSE BINDING PROTEIN; POL ETA PROTEIN; POL XI PROTEIN; PROTEIN VARIANT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ASSAY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; ION EXCHANGE CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN SUBUNIT; STOICHIOMETRY; WESTERN BLOTTING;

MAD2L2; PROCESSIVITY; REV3L; TLS; TWO-POLYMERASE LESION BYPASS;

CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; CISPLATIN; DNA; DNA POLYMERASE III; DNA PRIMERS; DNA REPAIR; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; FLUORESCEIN; HEK293 CELLS; HOLOENZYMES; HUMANS; MAD2 PROTEINS;

EID: 84896820727     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1324001111     Document Type: Article

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