Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages

  Lange, Sabine S ^a   Bedford, Ella ^a   Reh, Shelley ^a   Wittschieben, John P ^b   Carbajal, Steve ^c   Kusewitt, Donna F ^a,d   DiGiovanni, John ^c   Wood, Richard D ^a,d  

^a UNIVERSITY OF TEXAS   (United States)

^b Novo Nordisk Foundation   (Denmark)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d Graduate School of Biomedical Sciences at Houston   (United States)

Author keywords

Carcinogenesis; DNA replication; Double strand breaks; UV radiation

Indexed keywords

CYTOKERATIN 5; DNA POLYMERASE; DNA POLYMERASE ZETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL CULTURE; CELL DIVISION; CELL ISOLATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CHROMOSOMAL INSTABILITY; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME SUBUNIT; EPIDERMIS; GENE DELETION; GENOMIC INSTABILITY; HAIR DISEASE; IN VIVO STUDY; KERATINOCYTE; MALE; MAMMAL; MELANOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOSENSITIVITY; SKIN CARCINOGENESIS; SKIN DISEASE; SKIN EPITHELIUM; SQUAMOUS CELL CARCINOMA; TISSUE REGENERATION; ULTRAVIOLET B RADIATION;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; GENE DELETION; GENOMIC INSTABILITY; MICE; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 84874273451     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217425110     Document Type: Article

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