In vitro metabolism of monensin A: Microbial and human liver microsomes models

Xenobiotica

Volumn 44, Issue 4, 2014, Pages 326-335

  Rocha, Bruno A ^a   Assis, Marilda D ^a   Peti, Ana P F ^a   Moraes, Luiz A B ^a   Moreira, Fernanda L ^a   Lopes, Norberto P ^a   Pospíšil, Stanislav ^b   Gates, Paul J ^c   De Oliveira, Anderson R M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Cytochrome P450; LC ESI MS MS; Mass spectrometry; Microbial transformation; Polyether ionophore

Indexed keywords

12 HYDROXY MONENSIN A; ANTIBIOTIC AGENT; CYTOCHROME P450; DRUG METABOLITE; IONOPHORE; MONENSIN A; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CHEMICAL STRUCTURE; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; CUNNINGHAMELLA ECHINULATA; CUNNINGHAMELLA ELEGANS; DRUG METABOLISM; FERMENTATION MEDIUM; HUMAN; HUMAN CELL; HYDROXYLATION; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIVER METABOLISM; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; PROTON TRANSPORT; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; CUNNINGHAMELLA; HUMANS; IONOPHORES; LIVER; MASS SPECTROMETRY; MICROSOMES, LIVER; MONENSIN; MYCOSES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84896792078     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2013.845707     Document Type: Article

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