Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone

Analytica Chimica Acta

Volumn 742, Issue , 2012, Pages 80-89

  Bocato, Mariana Zuccherato ^a   Simões, Rodrigo Almeida ^a   Calixto, Leandro Augusto ^a   de Gaitani, Cristiane Masetto ^a   Pupo, Mônica Tallarico ^a   De Oliveira, Anderson Rodrigo Moraes ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Chiral analysis; Paliperidone; Polar organic mode; Risperidone; Solid phase microextraction; Stereoselective fungal biotransformation

Indexed keywords

CHIRAL ANALYSIS; FUNGAL BIOTRANSFORMATION; PALIPERIDONE; POLAR ORGANIC MODE; RISPERIDONE; SOLID-PHASE MICROEXTRACTION;

BIOCONVERSION; DESORPTION; DRUG PRODUCTS; ENANTIOMERS; ETHANOL; FUNGI; LIQUID CHROMATOGRAPHY; METABOLITES; METHANOL; STEREOSELECTIVITY;

EXTRACTION;

ALCOHOL; DRUG METABOLITE; METHANOL; PALIPERIDONE; RISPERIDONE; TRIETHYLAMINE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CUNNINGHAMELLA ECHINULATA; CUNNINGHAMELLA ELEGANS; DESORPTION; DRUG DETERMINATION; DRUG STRUCTURE; DRUG TRANSFORMATION; ENANTIOMER; FIBER; FLOW RATE; FUNGAL METABOLISM; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PRODUCT RECOVERY; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; SOLID PHASE MICROEXTRACTION; STEREOCHEMISTRY; TANDEM MASS SPECTROMETRY; TIME; VALIDATION PROCESS;

BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; CULTURE MEDIA; CUNNINGHAMELLA; ISOXAZOLES; MOLECULAR STRUCTURE; PYRIMIDINES; RISPERIDONE; SOLID PHASE MICROEXTRACTION; SOLVENTS; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

CUNNINGHAMELLA ECHINULATA; CUNNINGHAMELLA ELEGANS; FUNGI;

EID: 84864803386     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2012.05.056     Document Type: Article

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