Pinx1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse transcriptase (hTERT) plays dual roles

Journal of Biological Chemistry

Volumn 289, Issue 10, 2014, Pages 6886-6898

  Yoo, Jeong Eun ^a   Park, Young Nyun ^a,b   Oh, Bong Kyeong ^c  

^a Yonsei University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Hanyang University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINS;

DUAL ROLE; HUMAN TELOMERASE REVERSE TRANSCRIPTASE (HTERT); PROTEIN STABILITY; TELOMERASE; TELOMERES; TURN-OVER MECHANISMS;

CHROMOSOMES;

PINX1 PROTEIN; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERIC REPEAT BINDING FACTOR 1; UNCLASSIFIED DRUG;

ARTICLE; CELL IMMORTALIZATION; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA DAMAGE; GENE OVEREXPRESSION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STEADY STATE; TELOMERE HOMEOSTASIS; UBIQUITINATION;

CHROMOSOMAL INSTABILITY; DNA DAMAGE RESPONSE; TELOMERASE; TELOMERE DEFICIENCY; TELOMERES; TELOMERIC REPEAT-BINDING FACTOR 1; TERT; TUMOR CELL BIOLOGY; TUMOR SUPPRESSOR GENE;

HELA CELLS; HUMANS; PROTEIN STABILITY; TELOMERASE; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERIC REPEAT BINDING PROTEIN 1; TUMOR SUPPRESSOR PROTEINS;

EID: 84896783529     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.506006     Document Type: Article

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