메뉴 건너뛰기




Volumn 16, Issue 2, 2014, Pages 248-255

Androgens and prostate disease

Author keywords

Androgens; Male hypogonadism; Prostate; Testosterone

Indexed keywords

ABIRATERONE; ANDROGEN; ANDROSTANEDIOL; ANDROSTANOLONE; ANDROSTENEDIONE; DUTASTERIDE; ESTRADIOL; FINASTERIDE; GONADORELIN AGONIST; PRASTERONE SULFATE; PROSTATE SPECIFIC ANTIGEN; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; TESTOSTERONE ENANTATE;

EID: 84896755976     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.4103/1008-682X.122361     Document Type: Review
Times cited : (15)

References (104)
  • 1
    • 0035176554 scopus 로고    scopus 로고
    • A brief history of testosterone
    • DOI 10.1097/00005392-200102000-00004
    • Freeman ER, Bloom DA, McGuire EJ. A brief history of testosterone. J Urol 2001;165: 371-3. (Pubitemid 32060415)
    • (2001) Journal of Urology , vol.165 , Issue.2 , pp. 371-373
    • Freeman, E.R.1    Bloom, D.A.2    McGuire, E.J.3
  • 3
    • 0035097033 scopus 로고    scopus 로고
    • Longitudinal effects of aging on serum total and free testosterone levels in healthy men
    • DOI 10.1210/jc.86.2.724
    • Harman SM, Metter EJ, Tobin JD, Pearson J, Blackman MR. Baltimore Longitudinal Study of Aging. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 2001;86: 724-31. (Pubitemid 32207487)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.2 , pp. 724-731
    • Harman, S.M.1    Metter, E.J.2    Tobin, J.D.3    Pearson, J.4    Blackman, M.R.5
  • 4
  • 5
    • 77954409942 scopus 로고    scopus 로고
    • Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline
    • Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010;95: 2536-59.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2536-2559
    • Bhasin, S.1    Cunningham, G.R.2    Hayes, F.J.3    Matsumoto, A.M.4    Snyder, P.J.5
  • 6
    • 1442327856 scopus 로고    scopus 로고
    • Measurement of total serum testosterone in adult men: Comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry
    • DOI 10.1210/jc.2003-031287
    • Wang C, Catlin DH, Demers LM, Starcevic B, Swerdloff RS. Measurement of total serum testosterone in adult men: comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab 2004;89: 534-43. (Pubitemid 38269854)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.2 , pp. 534-543
    • Wang, C.1    Catlin, D.H.2    Demers, L.M.3    Starcevic, B.4    Swerdloff, R.S.5
  • 7
    • 84896763883 scopus 로고    scopus 로고
    • [Last accessed 2013 Nov 1]
    • CDC - Laboratory Quality Assurance and Standardization Programs. http://www.cdc. gov/labstandards/hs.html. [Last accessed 2013 Nov 1].
  • 8
    • 77954414397 scopus 로고    scopus 로고
    • EMAS Group. Identification of late-onset hypogonadism in middle-aged and elderly men
    • Wu FC, Tajar A, Beynon JM, Pye SR, Silman AJ, et al. EMAS Group. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med 2010;363: 123-35.
    • (2010) N Engl J Med , vol.363 , pp. 123-135
    • Wu, F.C.1    Tajar, A.2    Beynon, J.M.3    Pye, S.R.4    Silman, A.J.5
  • 15
    • 74549116339 scopus 로고    scopus 로고
    • Low free testosterone levels are associated with prevalence and incidence of depressive symptoms in older men
    • Joshi D, van Schoor NM, de Ronde W, Schaap LA, Comijs HC, et al. Low free testosterone levels are associated with prevalence and incidence of depressive symptoms in older men. Clin Endocrinol (Oxf) 2010;72: 232-40.
    • (2010) Clin Endocrinol (Oxf) , vol.72 , pp. 232-240
    • Joshi, D.1    Van Schoor, N.M.2    De Ronde, W.3    Schaap, L.A.4    Comijs, H.C.5
  • 18
    • 68049144803 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression)
    • Shores MM, Kivlahan DR, Sadak TI, Li EJ, Matsumoto AM. A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression). J Clin Psychiatry 2009;70: 1009-16.
    • (2009) J Clin Psychiatry , vol.70 , pp. 1009-1016
    • Shores, M.M.1    Kivlahan, D.R.2    Sadak, T.I.3    Li, E.J.4    Matsumoto, A.M.5
  • 19
    • 67649274349 scopus 로고    scopus 로고
    • Effects of testosterone replacement in middle-aged men with dysthymia: A randomized, placebo-controlled clinical trial
    • Seidman SN, Orr G, Raviv G, Levi R, Roose SP, et al. Effects of testosterone replacement in middle-aged men with dysthymia: a randomized, placebo-controlled clinical trial. J Clin Psychopharmacol 2009;29: 216-21.
    • (2009) J Clin Psychopharmacol , vol.29 , pp. 216-221
    • Seidman, S.N.1    Orr, G.2    Raviv, G.3    Levi, R.4    Roose, S.P.5
  • 20
    • 76149135996 scopus 로고    scopus 로고
    • Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: A randomized, double-blind, placebo-controlled study
    • Srinivas-Shankar U, Roberts SA, Connolly MJ, O'Connell MD, Adams JE, et al. Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab 2010;95: 639-50.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 639-650
    • Srinivas-Shankar, U.1    Roberts, S.A.2    Connolly, M.J.3    O'Connell, M.D.4    Adams, J.E.5
  • 21
    • 79951697311 scopus 로고    scopus 로고
    • Do the effects of testosterone on muscle strength, physical function, body composition, and quality of life persist six months after treatment in intermediate-frail and frail elderly men?
    • O'Connell MD, Roberts SA, Srinivas-Shankar U, Tajar A, Connolly MJ, et al. Do the effects of testosterone on muscle strength, physical function, body composition, and quality of life persist six months after treatment in intermediate-frail and frail elderly men? J Clin Endocrinol Metab 2011;96: 454-8.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 454-458
    • O'Connell, M.D.1    Roberts, S.A.2    Srinivas-Shankar, U.3    Tajar, A.4    Connolly, M.J.5
  • 22
    • 84869792056 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of testosterone gel on body composition and health-related quality-of-life in men with hypogonadal to low-normal levels of serum testosterone and symptoms of androgen deficiency over 6 months with 12 months open-label follow-up
    • Behre HM, Tammela TL, Arver S, Tolra JR, Bonifacio V, et al. A randomized, double-blind, placebo-controlled trial of testosterone gel on body composition and health-related quality-of-life in men with hypogonadal to low-normal levels of serum testosterone and symptoms of androgen deficiency over 6 months with 12 months open-label follow-up. Aging Male 2012;15: 198-207.
    • (2012) Aging Male , vol.15 , pp. 198-207
    • Behre, H.M.1    Tammela, T.L.2    Arver, S.3    Tolra, J.R.4    Bonifacio, V.5
  • 24
    • 70349918163 scopus 로고    scopus 로고
    • Sex hormones and frailty in older men: The osteoporotic fractures in men (MrOS) study
    • Osteoporotic Fractures in Men (MrOS) Research Group
    • Cawthon PM, Ensrud KE, Laughlin GA, Cauley JA, Dam TT, et al. Osteoporotic Fractures in Men (MrOS) Research Group. Sex hormones and frailty in older men: the osteoporotic fractures in men (MrOS) study. J Clin Endocrinol Metab 2009;94: 3806-15.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3806-3815
    • Cawthon, P.M.1    Ensrud, K.E.2    Laughlin, G.A.3    Cauley, J.A.4    Dam, T.T.5
  • 28
  • 29
    • 0020695971 scopus 로고
    • Obstructive sleep apnea syndrome induced by testosterone administration
    • Sandblom RE, Matsumoto AM, Schoene RB, Lee KA, Giblin EC, et al. Obstructive sleep apnea syndrome induced by testosterone administration. N Engl J Med 1983;308: 508-10. (Pubitemid 13195480)
    • (1983) New England Journal of Medicine , vol.308 , Issue.9 , pp. 508-510
    • Sandblom, R.E.1    Matsumoto, A.M.2    Schoene, R.B.3
  • 31
    • 84883507909 scopus 로고    scopus 로고
    • A UK epidemic of testosterone prescribing, 2001-2010
    • doi:10.1111/cen.12178. Epub 2013 Apr 5
    • Gan EH, Pattman S, H S Pearce S, Quinton R. A UK epidemic of testosterone prescribing, 2001-2010. Clin Endocrinol (Oxf) 2013; 79: 564-70. doi:10.1111/cen.12178. Epub 2013 Apr 5.
    • (2013) Clin Endocrinol (Oxf) , vol.79 , pp. 564-570
    • Gan, E.H.1    Pattman, S.2    Pearce S, H.S.3    Quinton, R.4
  • 32
    • 0001872893 scopus 로고
    • Sex determination and differentiation
    • E. Knobil, J. Neil Eds., 2nd Edition, Raven Press, New York
    • George FW and Wilson JD. Sex Determination and Differentiation. In: E. Knobil and J. Neil, Eds., Physiology of Reproduction, 2nd Edition, Raven Press, New York, 1994, p. 3-28.
    • (1994) Physiology of Reproduction , pp. 3-28
    • George, F.W.1    Wilson, J.D.2
  • 33
    • 4544285381 scopus 로고    scopus 로고
    • Dihydrotestosterone and the prostate: The scientific rationale for 5α-reductase inhibitors in the treatment of benign prostatic hyperplasia
    • DOI 10.1097/01.ju.0000139539.94828.29
    • Andriole G, Bruchovsky N, Chung LW, Matsumoto AM, Rittmaster R, et al. Dihydrotestosterone and the prostate: the scientific rationale for 5alpha-reductase inhibitors in the treatment of benign prostatic hyperplasia. J Urol 2004;172: 1399-403. (Pubitemid 39249729)
    • (2004) Journal of Urology , vol.172 , Issue.4 , pp. 1399-1403
    • Andriole, G.1    Bruchovsky, N.2    Chung, L.W.K.3    Matsumoto, A.M.4    Rittmaster, R.5    Roehrborn, C.6    Russell, D.7    Tindall, D.8
  • 34
    • 0035652497 scopus 로고    scopus 로고
    • 5alpha-reductase activity in the prostate
    • Steers WD. 5alpha-reductase activity in the prostate. Urology 2001;58: 17-24.
    • (2001) Urology , vol.58 , pp. 17-24
    • Steers, W.D.1
  • 35
    • 0036993579 scopus 로고    scopus 로고
    • Role of stroma in carcinogenesis of the prostate
    • DOI 10.1046/j.1432-0436.2002.700902.x
    • Cunha GR, Hayward SW, Wang YZ. Role of stroma in carcinogenesis of the prostate. Differentiation 2002;70: 473-85. (Pubitemid 36194313)
    • (2002) Differentiation , vol.70 , Issue.9-10 , pp. 473-485
    • Cunha, G.R.1    Hayward, S.W.2    Wang, Y.Z.3
  • 36
    • 84928580276 scopus 로고
    • Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins CH. Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1941;1: 293-7.
    • (1941) Cancer Res , vol.1 , pp. 293-297
    • Huggins, C.H.1
  • 37
    • 84870909367 scopus 로고    scopus 로고
    • Testosterone therapy in men with prostate cancer: Scientific and ethical considerations
    • Morgentaler A. Testosterone therapy in men with prostate cancer: scientific and ethical considerations. J Urol 2013;189:S26-33.
    • (2013) J Urol , vol.189
    • Morgentaler, A.1
  • 38
    • 33749234031 scopus 로고    scopus 로고
    • Testosterone and prostate cancer: An historical perspective on a modern myth
    • DOI 10.1016/j.eururo.2006.06.034, PII S0302283806007871
    • Morgentaler A. Testosterone and prostate cancer: an historical perspective on a modern myth. Eur Urol 2006;50: 935-9. (Pubitemid 44486489)
    • (2006) European Urology , vol.50 , Issue.5 , pp. 935-939
    • Morgentaler, A.1
  • 40
    • 0019478982 scopus 로고
    • The response of metastatic adenocarcinoma of the prostate to exogenous testosterone
    • Fowler JE Jr, Whitmore WF Jr. The response of metastatic adenocarcinoma of the prostate to exogenous testosterone. J Urol 1981;126: 372-5. (Pubitemid 11061000)
    • (1981) Journal of Urology , vol.126 , Issue.3 , pp. 372-375
    • Fowler Jr., J.E.1    Whitmore Jr., W.F.2
  • 41
    • 33749261655 scopus 로고    scopus 로고
    • Testosterone and Prostate Health: Debunking Myths Demands Evidence, Caution, and Good Clinical Judgment
    • DOI 10.1016/j.eururo.2006.06.033, PII S030228380600786X
    • Morales A. Testosterone and prostate health: Debunking myths demands evidence, caution, and good clinical judgment. Eur Urol 2006;50: 895-7. (Pubitemid 44486488)
    • (2006) European Urology , vol.50 , Issue.5 , pp. 895-897
    • Morales, A.1
  • 42
    • 0242692553 scopus 로고    scopus 로고
    • Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: Results of 1 year of treatment in men with prostatic intraepithelial neoplasia
    • DOI 10.1097/01.ju.0000091104.71869.8e
    • Rhoden EL, Morgentaler A. Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia. J Urol 2003;170: 2348-51. (Pubitemid 37413994)
    • (2003) Journal of Urology , vol.170 , Issue.6 , pp. 2348-2351
    • Rhoden, E.L.1    Morgentaler, A.2
  • 44
    • 77951738484 scopus 로고    scopus 로고
    • Testosterone replacement in prostate cancer survivors with hypogonadal symptoms
    • Leibowitz RL, Dorff TB, Tucker S, Symanowski J, Vogelzang NJ. Testosterone replacement in prostate cancer survivors with hypogonadal symptoms. BJU Int 2010;105: 1397-401.
    • (2010) BJU Int , vol.105 , pp. 1397-1401
    • Leibowitz, R.L.1    Dorff, T.B.2    Tucker, S.3    Symanowski, J.4    Vogelzang, N.J.5
  • 45
    • 84880036090 scopus 로고    scopus 로고
    • Testosterone replacement therapy in patients with prostate cancer after radical prostatectomy
    • Pastuszak AW, Pearlman AM, Lai WS, Godoy G, Sathyamoorthy K, et al. Testosterone replacement therapy in patients with prostate cancer after radical prostatectomy. J Urol 2013;190: 639-44.
    • (2013) J Urol , vol.190 , pp. 639-644
    • Pastuszak, A.W.1    Pearlman, A.M.2    Lai, W.S.3    Godoy, G.4    Sathyamoorthy, K.5
  • 46
    • 84872489211 scopus 로고    scopus 로고
    • Testosterone replacement therapy in the setting of prostate cancer treated with radiation
    • Pastuszak AW, Pearlman AM, Godoy G, Miles BJ, Lipshultz LI, et al. Testosterone replacement therapy in the setting of prostate cancer treated with radiation. Int J Impot Res 2013;25: 24-8.
    • (2013) Int J Impot Res , vol.25 , pp. 24-28
    • Pastuszak, A.W.1    Pearlman, A.M.2    Godoy, G.3    Miles, B.J.4    Lipshultz, L.I.5
  • 48
    • 77649247662 scopus 로고    scopus 로고
    • Serum testosterone is associated with aggressive prostate cancer in older men: Results from the Baltimore Longitudinal Study of Aging
    • Pierorazio PM, Ferrucci L, Kettermann A, Longo DL, Metter EJ, et al. Serum testosterone is associated with aggressive prostate cancer in older men: results from the Baltimore Longitudinal Study of Aging. BJU Int 2010;105: 824-9.
    • (2010) BJU Int , vol.105 , pp. 824-829
    • Pierorazio, P.M.1    Ferrucci, L.2    Kettermann, A.3    Longo, D.L.4    Metter, E.J.5
  • 49
    • 77952192447 scopus 로고    scopus 로고
    • Serum sex hormones and the 20-year risk of lower urinary tract symptoms in community-dwelling older men
    • Trifiro MD, Parsons JK, Palazzi-Churas K, Bergstrom J, Lakin C, et al. Serum sex hormones and the 20-year risk of lower urinary tract symptoms in community-dwelling older men. BJU Int 2010;105: 1554-9.
    • (2010) BJU Int , vol.105 , pp. 1554-1559
    • Trifiro, M.D.1    Parsons, J.K.2    Palazzi-Churas, K.3    Bergstrom, J.4    Lakin, C.5
  • 50
    • 77955712006 scopus 로고    scopus 로고
    • Prospective study of serum dihydrotestosterone and subsequent risk of benign prostatic hyperplasia in community dwelling men: The Rancho Bernardo Study
    • Parsons JK, Palazzi-Churas K, Bergstrom J, Barrett-Connor E. Prospective study of serum dihydrotestosterone and subsequent risk of benign prostatic hyperplasia in community dwelling men: The Rancho Bernardo Study. J Urol 2010;184: 1040-4.
    • (2010) J Urol , vol.184 , pp. 1040-1044
    • Parsons, J.K.1    Palazzi-Churas, K.2    Bergstrom, J.3    Barrett-Connor, E.4
  • 52
    • 0033565714 scopus 로고    scopus 로고
    • Serum testosterone and sex hormone-binding globulin concentrations and the risk of prostate carcinoma: A longitudinal study
    • DOI 10.1002/(SICI)1097-0142(19990715)86:2<312::AID-CNCR15>3.0.CO;2- 7
    • Heikkila R, Aho K, Heliovaara M, Hakama M, Marniemi J, et al. Serum testosterone and sex hormone-binding globulin concentrations and the risk of prostate carcinoma: a longitudinal study. Cancer 1999;86: 312-5. (Pubitemid 29327588)
    • (1999) Cancer , vol.86 , Issue.2 , pp. 312-315
    • Heikkila, R.1    Aho, K.2    Heliovaara, M.3    Hakama, M.4    Marniemi, J.5    Reunanen, A.6    Knekt, P.7
  • 53
    • 39149084101 scopus 로고    scopus 로고
    • Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies
    • DOI 10.1093/jnci/djm323
    • Endogenous Hormones and Prostate Cancer Collaborative Group, Roddam AW, Allen NE, Appleby P, Key TJ. Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies. J Natl Cancer Inst 2008;100: 170-83. (Pubitemid 351480553)
    • (2008) Journal of the National Cancer Institute , vol.100 , Issue.3 , pp. 170-183
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3    Key, T.J.4
  • 54
    • 39149134348 scopus 로고    scopus 로고
    • Getting over testosterone: Postulating a fresh start for etiologic studies of prostate cancer
    • DOI 10.1093/jnci/djm329
    • Carpenter WR, Robinson WR, Godley PA. Getting over testosterone: Postulating a fresh start for etiologic studies of prostate cancer. J Natl Cancer Inst 2008;100: 158-9. (Pubitemid 351480558)
    • (2008) Journal of the National Cancer Institute , vol.100 , Issue.3 , pp. 158-159
    • Carpenter, W.R.1    Robinson, W.R.2    Godley, P.A.3
  • 57
    • 0028358995 scopus 로고
    • Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls
    • Behre HM, Bohmeyer J, Nieschlag E. Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls. Clin Endocrinol (Oxf) 1994;40: 341-9. (Pubitemid 24194627)
    • (1994) Clinical Endocrinology , vol.40 , Issue.3 , pp. 341-349
    • Behre, H.M.1    Bohmeyer, J.2    Nieschlag, E.3
  • 58
    • 0036868435 scopus 로고    scopus 로고
    • Prostate-specific antigen changes in hypogonadal men treated with testosterone replacement
    • Gerstenbluth RE, Maniam PN, Corty EW, Seftel AD. Prostate-specific antigen changes in hypogonadal men treated with testosterone replacement. J Androl 2002;23: 922-6. (Pubitemid 36300984)
    • (2002) Journal of Andrology , vol.23 , Issue.6 , pp. 922-926
    • Gerstenbluth, R.E.1    Maniam, P.N.2    Corty, E.W.3    Seftel, A.D.4
  • 62
    • 63249122661 scopus 로고    scopus 로고
    • PLCO Project Team. Mortality results from a randomized prostate-cancer screening trial
    • Andriole GL, Crawford ED, Grubb RL 3rd, Buys SS, Chia D, et al. PLCO Project Team. Mortality results from a randomized prostate-cancer screening trial. N Engl J Med 2009;360: 1310-9.
    • (2009) N Engl J Med , vol.360 , pp. 1310-1319
    • Andriole, G.L.1    Crawford, E.D.2    Grubb III, R.L.3    Buys, S.S.4    Chia, D.5
  • 63
    • 63249118690 scopus 로고    scopus 로고
    • Screening and prostate-cancer mortality in a randomized European study
    • ERSPC Investigators
    • Schroder FH, Hugosson J, Roobol MJ, Tammela TL, Ciatto S, et al. ERSPC Investigators. Screening and prostate-cancer mortality in a randomized European study. N Engl J Med 2009;360: 1320-8.
    • (2009) N Engl J Med , vol.360 , pp. 1320-1328
    • Schroder, F.H.1    Hugosson, J.2    Roobol, M.J.3    Tammela, T.L.4    Ciatto, S.5
  • 64
    • 84896755125 scopus 로고    scopus 로고
    • identifier: NCT00799617 [Last accessed on 2013 July 24]
    • The testosterone trial in older men. http://clinicaltrials.gov/show/ NCT00799617. ClinicalTrials.gov identifier: NCT00799617. [Last accessed on 2013 July 24].
    • The Testosterone Trial in Older Men
  • 65
    • 0030337791 scopus 로고    scopus 로고
    • The effects of chronic high dose androgen or estrogen treatment on the human prostate [corrected]
    • Jin B, Turner L, Walters WA, Handelsman DJ. The effects of chronic high dose androgen or estrogen treatment on the human prostate [corrected]. J Clin Endocrinol Metab 1996;81: 4290-5.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4290-4295
    • Jin, B.1    Turner, L.2    Walters, W.A.3    Handelsman, D.J.4
  • 66
    • 1842584526 scopus 로고    scopus 로고
    • The effect of exogenous testosterone on total and free prostate specific antigen levels in healthy young men
    • Cooper CS, MacIndoe JH, Perry PJ, Yates WR, Williams RD. The effect of exogenous testosterone on total and free prostate specific antigen levels in healthy young men. J Urol 1996;156: 438-41.
    • (1996) J Urol , vol.156 , pp. 438-441
    • Cooper, C.S.1    MacIndoe, J.H.2    Perry, P.J.3    Yates, W.R.4    Williams, R.D.5
  • 69
    • 79958287449 scopus 로고    scopus 로고
    • Dutasteride reduces prostate size and prostate specific antigen in older hypogonadal men with benign prostatic hyperplasia undergoing testosterone replacement therapy
    • Page ST, Hirano L, Gilchriest J, Dighe M, Amory JK, et al. Dutasteride reduces prostate size and prostate specific antigen in older hypogonadal men with benign prostatic hyperplasia undergoing testosterone replacement therapy. J Urol 2011;186: 191-7.
    • (2011) J Urol , vol.186 , pp. 191-197
    • Page, S.T.1    Hirano, L.2    Gilchriest, J.3    Dighe, M.4    Amory, J.K.5
  • 72
    • 84896773583 scopus 로고    scopus 로고
    • Characterization of a new type 3 5α-reductase an enzyme involves in the biosynthesis of dihydrotestosterone highly expressed in skin mammary glands breast cancer cell lines and adipose tissue and inhibited by finasteride
    • Washington, DC;
    • Kazutoshi Y, Labrie F, Luu-The V. Characterization of a new type 3 5α-reductase, an enzyme involves in the biosynthesis of dihydrotestosterone, highly expressed in skin, mammary glands, breast cancer cell lines and adipose tissue, and inhibited by Finasteride. In: 91st Annual Meeting of the Endocrine Society. Washington, DC; 2009.
    • (2009) 91st Annual Meeting of the Endocrine Society
    • Kazutoshi, Y.1    Labrie, F.2    Luu-The, V.3
  • 75
    • 0026806486 scopus 로고
    • The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group
    • Gormley GJ, Stoner E, Bruskewitz RC, Imperato-McGinley J, Walsh PC, et al. The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. N Engl J Med 1992;327: 1185-91.
    • (1992) N Engl J Med , vol.327 , pp. 1185-1191
    • Gormley, G.J.1    Stoner, E.2    Bruskewitz, R.C.3    Imperato-Mcginley, J.4    Walsh, P.C.5
  • 77
    • 0036754256 scopus 로고    scopus 로고
    • Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia
    • DOI 10.1016/S0090-4295(02)01905-2, PII S0090429502019052
    • Roehrborn CG, Boyle P, Nickel JC, Hoefner K, Andriole G. ARIA3001 ARIA3002 and ARIA3003 Study Investigators. Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia. Urology 2002;60: 434-41. (Pubitemid 35292169)
    • (2002) Urology , vol.60 , Issue.3 , pp. 434-441
    • Roehrborn, C.G.1    Boyle, P.2    Nickel J.Curtis3    Hoefner, K.4    Andriole, G.5
  • 78
    • 80052335440 scopus 로고    scopus 로고
    • Dutasteride improves outcomes of benign prostatic hyperplasia when evaluated for prostate cancer risk reduction: Secondary analysis of the Reduction by Dutasteride of prostate Cancer Events (REDUCE) trial
    • Roehrborn CG, Nickel JC, Andriole GL, Gagnier RP, Black L, et al. Dutasteride improves outcomes of benign prostatic hyperplasia when evaluated for prostate cancer risk reduction: secondary analysis of the Reduction by Dutasteride of prostate Cancer Events (REDUCE) trial. Urology 2011;78: 641-6.
    • (2011) Urology , vol.78 , pp. 641-646
    • Roehrborn, C.G.1    Nickel, J.C.2    Andriole, G.L.3    Gagnier, R.P.4    Black, L.5
  • 79
    • 33748590535 scopus 로고    scopus 로고
    • Drug insight: 5α-reductase inhibitors for the treatment of benign prostatic hyperplasia
    • DOI 10.1038/ncpuro0577, PII NCPURO0577
    • Marberger M. Drug insight: 5alpha-reductase inhibitors for the treatment of benign prostatic hyperplasia. Nat Clin Pract Urol 2006;3: 495-503. (Pubitemid 44377540)
    • (2006) Nature Clinical Practice Urology , vol.3 , Issue.9 , pp. 495-503
    • Marberger, M.1
  • 80
  • 82
    • 10744227703 scopus 로고    scopus 로고
    • Prevention of prostate cancer with finasteride
    • Ross RK, Skinner E, Cote RJ. Prevention of prostate cancer with finasteride. N Engl J Med 2003;349: 1569-72.
    • (2003) N Engl J Med , vol.349 , pp. 1569-1572
    • Ross, R.K.1    Skinner, E.2    Cote, R.J.3
  • 83
    • 0038678851 scopus 로고    scopus 로고
    • The prevention of prostate cancer - The dilemma continues
    • DOI 10.1056/NEJMe038109
    • Scardino PT. The prevention of prostate cancer - the dilemma continues. N Engl J Med 2003;349: 297-9. (Pubitemid 36859482)
    • (2003) New England Journal of Medicine , vol.349 , Issue.3 , pp. 297-299
    • Scardino, P.T.1
  • 84
    • 4544248276 scopus 로고    scopus 로고
    • Chemoprevention of prostate cancer in men at high risk: Rationale and design of the reduction by dutasteride of prostate cancer events (reduce) trial
    • DOI 10.1097/01.ju.0000139320.78673.2a
    • Andriole G, Bostwick D, Brawley O, Gomella L, Marberger M, et al. Chemoprevention of prostate cancer in men at high risk: rationale and design of the reduction by dutasteride of prostate cancer events (REDUCE) trial. J Urol 2004;172: 1314-7. (Pubitemid 39249705)
    • (2004) Journal of Urology , vol.172 , Issue.4 , pp. 1314-1317
    • Andriole, G.1    Bostwick, D.2    Brawley, O.3    Gomella, L.4    Marberger, M.5    Tindall, D.6    Breed, S.7    Somerville, M.8    Rittmaster, R.9
  • 86
    • 12844279803 scopus 로고    scopus 로고
    • The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate
    • DOI 10.1016/j.urology.2004.08.042, PII S0090429504010155
    • Iczkowski KA, Qiu J, Qian J, Somerville MC, Rittmaster RS, et al. The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate. Urology 2005;65: 76-82. (Pubitemid 40169609)
    • (2005) Urology , vol.65 , Issue.1 , pp. 76-82
    • Iczkowski, K.A.1    Qiu, J.2    Qian, J.3    Somerville, M.C.4    Rittmaster, R.S.5    Andriole, G.L.6    Bostwick, D.G.7
  • 87
    • 84863230584 scopus 로고    scopus 로고
    • Effect of testosterone supplementation with and without a dual 5alpha-reductase inhibitor on fat-free mass in men with suppressed testosterone production: A randomized controlled trial
    • Bhasin S, Travison TG, Storer TW, Lakshman K, Kaushik M, et al. Effect of testosterone supplementation with and without a dual 5alpha-reductase inhibitor on fat-free mass in men with suppressed testosterone production: a randomized controlled trial. JAMA 2012;307: 931-9.
    • (2012) JAMA , vol.307 , pp. 931-939
    • Bhasin, S.1    Travison, T.G.2    Storer, T.W.3    Lakshman, K.4    Kaushik, M.5
  • 88
    • 0035030610 scopus 로고    scopus 로고
    • Tissue effects of saw palmetto and finasteride: Use of biopsy cores for in situ quantification of prostatic androgens
    • DOI 10.1016/S0090-4295(00)01052-9, PII S0090429500010529
    • Marks LS, Hess DL, Dorey FJ, Luz Macairan M, Cruz Santos PB, et al. Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens. Urology 2001;57: 999-1005. (Pubitemid 32405333)
    • (2001) Urology , vol.57 , Issue.5 , pp. 999-1005
    • Marks, L.S.1    Hess, D.L.2    Dorey, F.J.3    Luz Macairan, M.4    Cruz Santos, P.B.5    Tyler, V.E.6
  • 89
    • 0026503988 scopus 로고
    • Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia
    • McConnell JD, Wilson JD, George FW, Geller J, Pappas F, et al. Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia. J Clin Endocrinol Metab 1992;74: 505-8.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 505-508
    • McConnell, J.D.1    Wilson, J.D.2    George, F.W.3    Geller, J.4    Pappas, F.5
  • 90
    • 0027767192 scopus 로고
    • Androgen metabolism in men receiving finasteride before prostatectomy
    • Norman RW, Coakes KE, Wright AS, Rittmaster RS. Androgen metabolism in men receiving finasteride before prostatectomy. J Urol 1993;150: 1736-9. (Pubitemid 24346938)
    • (1993) Journal of Urology , vol.150 , Issue.5 , pp. 1736-1739
    • Norman, R.W.1    Coakes, K.E.2    Wright, A.S.3    Rittmaster, R.S.4
  • 91
    • 52949132642 scopus 로고    scopus 로고
    • Effect of dutasteride on intraprostatic androgen levels in men with benign prostatic hyperplasia or prostate cancer
    • Rittmaster R, Hahn RG, Ray P, Shannon JB, Wurzel R. Effect of dutasteride on intraprostatic androgen levels in men with benign prostatic hyperplasia or prostate cancer. Urology 2008;72: 808-12.
    • (2008) Urology , vol.72 , pp. 808-812
    • Rittmaster, R.1    Hahn, R.G.2    Ray, P.3    Shannon, J.B.4    Wurzel, R.5
  • 94
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
    • Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 2008;68: 4447-54.
    • (2008) Cancer Res , vol.68 , pp. 4447-4454
    • Montgomery, R.B.1    Mostaghel, E.A.2    Vessella, R.3    Hess, D.L.4    Kalhorn, T.F.5
  • 96
    • 79951714359 scopus 로고    scopus 로고
    • Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: A randomized-controlled trial
    • Page ST, Lin DW, Mostaghel EA, Marck BT, Wright JL, et al. Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial. J Clin Endocrinol Metab 2011;96: 430-7.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 430-437
    • Page, S.T.1    Lin, D.W.2    Mostaghel, E.A.3    Marck, B.T.4    Wright, J.L.5
  • 98
    • 80051963331 scopus 로고    scopus 로고
    • Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
    • Chang KH, Li R, Papari-Zareei M, Watumull L, Zhao YD, et al. Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer. Proc Natl Acad Sci U S A 2011;108: 13728-33.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13728-13733
    • Chang, K.H.1    Li, R.2    Papari-Zareei, M.3    Watumull, L.4    Zhao, Y.D.5
  • 99
    • 80052827038 scopus 로고    scopus 로고
    • Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
    • Mostaghel EA, Marck BT, Plymate SR, Vessella RL, Balk S, et al. Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants. Clin Cancer Res 2011;17: 5913-25.
    • (2011) Clin Cancer Res , vol.17 , pp. 5913-5925
    • Mostaghel, E.A.1    Marck, B.T.2    Plymate, S.R.3    Vessella, R.L.4    Balk, S.5
  • 101
    • 0021332976 scopus 로고
    • Comparative aspects of prostatic growth and androgen metabolism with aging in the dog versus the rat
    • Berry SJ, Isaacs JT. Comparative aspects of prostatic growth and androgen metabolism with aging in the dog versus the rat. Endocrinology 1984;114: 511-20. (Pubitemid 14183252)
    • (1984) Endocrinology , vol.114 , Issue.2 , pp. 511-520
    • Berry, S.J.1    Isaacs, J.T.2
  • 102
    • 0033305674 scopus 로고    scopus 로고
    • Androgen-induced regrowth in the castrated rat ventral prostate: Role of 5α-reductase
    • Wright AS, Douglas RC, Thomas LN, Lazier CB, Rittmaster RS. Androgen-induced regrowth in the castrated rat ventral prostate: role of 5alpha-reductase. Endocrinology 1999;140: 4509-15. (Pubitemid 30666115)
    • (1999) Endocrinology , vol.140 , Issue.10 , pp. 4509-4515
    • Wright, A.S.1    Douglas, R.C.2    Thomas, L.N.3    Lazier, C.B.4    Rittmaster, R.S.5
  • 103
    • 57649176913 scopus 로고    scopus 로고
    • Shifting the paradigm of testosterone and prostate cancer: The saturation model and the limits of androgen-dependent growth
    • Morgentaler A, Traish AM. Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth. Eur Urol 2009;55: 310-20.
    • (2009) Eur Urol , vol.55 , pp. 310-320
    • Morgentaler, A.1    Traish, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.