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Volumn 189, Issue 1 SUPPL, 2013, Pages

Testosterone therapy in men with prostate cancer: Scientific and ethical considerations

Author keywords

androgens; hypogonadism; prostatic neoplasms; testosterone

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; GONADORELIN AGONIST; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE;

EID: 84870909367     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2012.11.028     Document Type: Review
Times cited : (30)

References (50)
  • 1
    • 35648968683 scopus 로고    scopus 로고
    • Testosterone replacement therapy and prostate cancer
    • A. Morgentaler Testosterone replacement therapy and prostate cancer Urol Clin North Am 34 2007 555
    • (2007) Urol Clin North Am , vol.34 , pp. 555
    • Morgentaler, A.1
  • 2
    • 51349157234 scopus 로고    scopus 로고
    • Androgen replacement in men undergoing treatment for prostate cancer
    • E.L. Rhoden, M.A. Averback, P.E. Teloken Androgen replacement in men undergoing treatment for prostate cancer J Sex Med 5 2008 2202
    • (2008) J Sex Med , vol.5 , pp. 2202
    • Rhoden, E.L.1    Averback, M.A.2    Teloken, P.E.3
  • 3
    • 33749234031 scopus 로고    scopus 로고
    • Testosterone and prostate cancer: An historical perspective on a modern myth
    • A. Morgentaler Testosterone and prostate cancer: an historical perspective on a modern myth Eur Urol 50 2006 935
    • (2006) Eur Urol , vol.50 , pp. 935
    • Morgentaler, A.1
  • 4
    • 4143066958 scopus 로고    scopus 로고
    • Androgen replacement after curative radical prostatectomy for prostate cancer in hypogonadal men
    • J.M. Kaufman, R.J. Graydon Androgen replacement after curative radical prostatectomy for prostate cancer in hypogonadal men J Urol 172 2004 920
    • (2004) J Urol , vol.172 , pp. 920
    • Kaufman, J.M.1    Graydon, R.J.2
  • 5
    • 12544256922 scopus 로고    scopus 로고
    • Testosterone replacement therapy after primary treatment for prostate cancer
    • P.K. Agarwal, M.G. Oefelein Testosterone replacement therapy after primary treatment for prostate cancer J Urol 173 2005 533
    • (2005) J Urol , vol.173 , pp. 533
    • Agarwal, P.K.1    Oefelein, M.G.2
  • 6
    • 33846688614 scopus 로고    scopus 로고
    • Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy
    • M.F. Sarosdy Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy Cancer 109 2007 536
    • (2007) Cancer , vol.109 , pp. 536
    • Sarosdy, M.F.1
  • 8
    • 2442543161 scopus 로고    scopus 로고
    • Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone density in hypogonadal men
    • C. Wang, G. Cunningham, A. Dobs, A. Iranmanesh, A.M. Matsumoto, P.J. Snyder Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone density in hypogonadal men J Clin Endocrinol Metab 89 2004 2085
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2085
    • Wang, C.1    Cunningham, G.2    Dobs, A.3    Iranmanesh, A.4    Matsumoto, A.M.5    Snyder, P.J.6
  • 10
    • 48749083358 scopus 로고    scopus 로고
    • Guilt by association: A historical perspective on Huggins, testosterone therapy, and prostate cancer
    • A. Morgentaler Guilt by association: a historical perspective on Huggins, testosterone therapy, and prostate cancer J Sex Med 5 2008 1834
    • (2008) J Sex Med , vol.5 , pp. 1834
    • Morgentaler, A.1
  • 11
    • 84928580276 scopus 로고
    • Studies on prostatic cancer I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • C. Huggins, C.V. Hodges Studies on prostatic cancer I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate Cancer Res 1 1941 293
    • (1941) Cancer Res , vol.1 , pp. 293
    • Huggins, C.1    Hodges, C.V.2
  • 12
    • 0014154355 scopus 로고
    • Response of men with advanced prostatic carcinoma to exogenous administration of testosterone
    • G.R. Prout, W.R. Brewer Response of men with advanced prostatic carcinoma to exogenous administration of testosterone Cancer 20 1967 1871
    • (1967) Cancer , vol.20 , pp. 1871
    • Prout, G.R.1    Brewer, W.R.2
  • 13
    • 0019478982 scopus 로고
    • The response of metastatic adenocarcinoma of the prostate to exogenous testosterone
    • J.E. Fowler Jr, W.F. Whitmore Jr The response of metastatic adenocarcinoma of the prostate to exogenous testosterone J Urol 126 1981 372
    • (1981) J Urol , vol.126 , pp. 372
    • Fowler Jr., J.E.1    Whitmore Jr., W.F.2
  • 14
    • 0034905094 scopus 로고    scopus 로고
    • Is the flare phenomenon clinically significant?
    • G.J. Bubley Is the flare phenomenon clinically significant? Urology 58 suppl 2001 5
    • (2001) Urology , vol.58 , Issue.SUPPL. , pp. 5
    • Bubley, G.J.1
  • 16
    • 1642458222 scopus 로고    scopus 로고
    • Risks of testosterone-replacement therapy and recommendations for monitoring
    • E.L. Rhoden, A. Morgentaler Risks of testosterone-replacement therapy and recommendations for monitoring N Engl J Med 350 2004 482
    • (2004) N Engl J Med , vol.350 , pp. 482
    • Rhoden, E.L.1    Morgentaler, A.2
  • 17
    • 40849135468 scopus 로고    scopus 로고
    • The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer
    • D.J. Tindall, R.S. Rittmaster The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer J Urol 179 2008 1235
    • (2008) J Urol , vol.179 , pp. 1235
    • Tindall, D.J.1    Rittmaster, R.S.2
  • 18
    • 59349085429 scopus 로고    scopus 로고
    • Shifting the paradigm of testosterone and prostate cancer: The saturation model and the limits of androgen stimulation of prostate cancer
    • Epub ahead of print
    • A. Morgentaler, A.M. Traish Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen stimulation of prostate cancer Eur Urol 2008 Epub ahead of print
    • (2008) Eur Urol
    • Morgentaler, A.1    Traish, A.M.2
  • 19
    • 0023714781 scopus 로고
    • Validation of the exchange assay for the measurement of androgen receptors in human and dog prostates
    • A.M. Traish, D.F. Williams, N.D. Hoffman, H.H. Wotan Validation of the exchange assay for the measurement of androgen receptors in human and dog prostates Prog Clin Biol Res 262 1988 145
    • (1988) Prog Clin Biol Res , vol.262 , pp. 145
    • Traish, A.M.1    Williams, D.F.2    Hoffman, N.D.3    Wotan, H.H.4
  • 20
    • 0022119914 scopus 로고
    • Androgen receptor levels and androgen contents in the prostate lobes of intact and testosterone-treated Noble rats
    • S.M. Ho, D. Damassa, P.W. Kwan, H.S. Seto, I. Leav Androgen receptor levels and androgen contents in the prostate lobes of intact and testosterone-treated Noble rats J Androl 6 1985 279
    • (1985) J Androl , vol.6 , pp. 279
    • Ho, S.M.1    Damassa, D.2    Kwan, P.W.3    Seto, H.S.4    Leav, I.5
  • 21
    • 0029240370 scopus 로고
    • Finasteride dose-dependently reduces the proliferation rate of the LnCap human prostatic cancer cell line in vitro
    • M. Bologna, P. Muzi, L. Biordi, C. Festuccia, C. Vicentini Finasteride dose-dependently reduces the proliferation rate of the LnCap human prostatic cancer cell line in vitro Urology 45 1995 282
    • (1995) Urology , vol.45 , pp. 282
    • Bologna, M.1    Muzi, P.2    Biordi, L.3    Festuccia, C.4    Vicentini, C.5
  • 22
    • 13844262629 scopus 로고    scopus 로고
    • Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells
    • J.T. Arnold, H. Le, K.K. McFann, M.R. Blackman Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells Am J Physiol Endocrinol Metab 288 2005 E573
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. 573
    • Arnold, J.T.1    Le, H.2    McFann, K.K.3    Blackman, M.R.4
  • 23
    • 0024340648 scopus 로고
    • Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide)
    • J.M. Kuhn, T. Billebaud, H. Navratil, A. Moulonguet, J. Fiet, P. Grise Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide) N Engl J Med 321 1989 413
    • (1989) N Engl J Med , vol.321 , pp. 413
    • Kuhn, J.M.1    Billebaud, T.2    Navratil, H.3    Moulonguet, A.4    Fiet, J.5    Grise, P.6
  • 24
    • 0035046991 scopus 로고    scopus 로고
    • The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin: Initial results of endocrinological and biochemical efficacies in patients with prostate cancer
    • K. Tomera, D. Gleason, M. Gittelman, W. Moseley, N. Zinner, M. Murdoch The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin: initial results of endocrinological and biochemical efficacies in patients with prostate cancer J Urol 165 2001 1585
    • (2001) J Urol , vol.165 , pp. 1585
    • Tomera, K.1    Gleason, D.2    Gittelman, M.3    Moseley, W.4    Zinner, N.5    Murdoch, M.6
  • 25
    • 0024574079 scopus 로고
    • The influence of reversible androgen deprivation on serum prostate-specific antigen levels in men with benign prostatic hyperplasia
    • J.P. Weber, J.E. Oesterling, C.A. Peters, A.W. Partin, D.W. Chan, P.C. Walsh The influence of reversible androgen deprivation on serum prostate-specific antigen levels in men with benign prostatic hyperplasia J Urol 141 1989 987
    • (1989) J Urol , vol.141 , pp. 987
    • Weber, J.P.1    Oesterling, J.E.2    Peters, C.A.3    Partin, A.W.4    Chan, D.W.5    Walsh, P.C.6
  • 26
    • 33746543255 scopus 로고    scopus 로고
    • The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: A review and clinical recommendations
    • L.S. Marks, G.L. Andriole, J.M. Fitzpatrick, C.C. Schulman, C.G. Roehrborn The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: a review and clinical recommendations J Urol 176 2006 868
    • (2006) J Urol , vol.176 , pp. 868
    • Marks, L.S.1    Andriole, G.L.2    Fitzpatrick, J.M.3    Schulman, C.C.4    Roehrborn, C.G.5
  • 27
    • 0028880526 scopus 로고
    • Physiologic variations of serum testosterone within the normal range do not affect serum prostate-specific antigen
    • J.R. Monath, D.L. McCullough, L.J. Hart, J.P. Jarow Physiologic variations of serum testosterone within the normal range do not affect serum prostate-specific antigen Urology 46 1995 58
    • (1995) Urology , vol.46 , pp. 58
    • Monath, J.R.1    McCullough, D.L.2    Hart, L.J.3    Jarow, J.P.4
  • 28
    • 0035030328 scopus 로고    scopus 로고
    • Are serum hormones associated with the risk of prostate cancer? Prospective results from the Massachusetts Male Aging Study
    • B.A. Mohr, H.A. Feldman, L.A. Kalish, C. Longcope, J.B. McKinlay Are serum hormones associated with the risk of prostate cancer? Prospective results from the Massachusetts Male Aging Study Urology 57 2001 930
    • (2001) Urology , vol.57 , pp. 930
    • Mohr, B.A.1    Feldman, H.A.2    Kalish, L.A.3    Longcope, C.4    McKinlay, J.B.5
  • 29
    • 0031975843 scopus 로고    scopus 로고
    • Effect of exogenous testosterone on prostate volume, serum and semen prostate specific antigen levels in healthy young men
    • C.S. Cooper, P.J. Perry, A.E. Sparks, J.H. MacIndoe, W.R. Yates, R.D. Williams Effect of exogenous testosterone on prostate volume, serum and semen prostate specific antigen levels in healthy young men J Urol 159 1998 441
    • (1998) J Urol , vol.159 , pp. 441
    • Cooper, C.S.1    Perry, P.J.2    Sparks, A.E.3    MacIndoe, J.H.4    Yates, W.R.5    Williams, R.D.6
  • 30
    • 8944233864 scopus 로고    scopus 로고
    • The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men
    • S. Bhasin, T.W. Storer, N. Berman, C. Callegari, B. Clevenger, J. Phillips The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men N Engl J Med 335 1996 1
    • (1996) N Engl J Med , vol.335 , pp. 1
    • Bhasin, S.1    Storer, T.W.2    Berman, N.3    Callegari, C.4    Clevenger, B.5    Phillips, J.6
  • 31
    • 0012619789 scopus 로고    scopus 로고
    • AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function
    • C. Steidle, S. Schwartz, K. Jacoby, T. Sebree, T. Smith, R. Bachand AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function J Clin Endocrinol Metab 88 2003 2673
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2673
    • Steidle, C.1    Schwartz, S.2    Jacoby, K.3    Sebree, T.4    Smith, T.5    Bachand, R.6
  • 32
    • 29144469309 scopus 로고    scopus 로고
    • Adverse events associated with testosterone replacement in middle-aged and older men: A meta-analysis of randomized, placebo-controlled trials
    • O.M. Calof, A.B. Singh, M.L. Lee, A.M. Kenny, R.J. Urban, J.L. Tenover Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials J Gerontol A Biol Sci Med Sci 60 2005 1451
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , pp. 1451
    • Calof, O.M.1    Singh, A.B.2    Lee, M.L.3    Kenny, A.M.4    Urban, R.J.5    Tenover, J.L.6
  • 33
    • 33644753687 scopus 로고    scopus 로고
    • Influence of demographic factors and biochemical characteristics on the prostate-specific antigen (PSA) response to testosterone replacement therapy
    • E.L. Rhoden, A. Morgentaler Influence of demographic factors and biochemical characteristics on the prostate-specific antigen (PSA) response to testosterone replacement therapy Int J Impot Res 18 2006 201
    • (2006) Int J Impot Res , vol.18 , pp. 201
    • Rhoden, E.L.1    Morgentaler, A.2
  • 35
    • 39149084101 scopus 로고    scopus 로고
    • Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies
    • Endogenous Hormones Prostate Cancer Collaborative Group
    • Endogenous Hormones Prostate Cancer Collaborative Group A.W. Roddam, N.E. Allen, P. Appleby, T.J. Key Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies J Natl Cancer Inst 100 2008 170
    • (2008) J Natl Cancer Inst , vol.100 , pp. 170
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3    Key, T.J.4
  • 36
    • 34547177850 scopus 로고    scopus 로고
    • Testosterone deficiency and prostate cancer: Emerging recognition of an important and troubling relationship
    • A. Morgentaler Testosterone deficiency and prostate cancer: emerging recognition of an important and troubling relationship Eur Urol 52 2007 623
    • (2007) Eur Urol , vol.52 , pp. 623
    • Morgentaler, A.1
  • 37
    • 34547156657 scopus 로고    scopus 로고
    • Preoperative serum testosterone level as an independent predictor of treatment failure following radical prostatectomy
    • S. Yamamoto, J. Yonese, S. Kawakami, Y. Ohkubo, M. Tatokoro, Y. Komai Preoperative serum testosterone level as an independent predictor of treatment failure following radical prostatectomy Eur Urol 52 2007 696
    • (2007) Eur Urol , vol.52 , pp. 696
    • Yamamoto, S.1    Yonese, J.2    Kawakami, S.3    Ohkubo, Y.4    Tatokoro, M.5    Komai, Y.6
  • 38
    • 36249029994 scopus 로고    scopus 로고
    • The safety and efficacy of testosterone replacement therapy following radical prostatectomy
    • abstract 1164
    • M. Khera, J. Colen, E. Grober, B.B. Najari, L. Murthy, D.J. Lamb The safety and efficacy of testosterone replacement therapy following radical prostatectomy J Urol 177 suppl 2007 384 abstract 1164
    • (2007) J Urol , vol.177 , Issue.SUPPL. , pp. 384
    • Khera, M.1    Colen, J.2    Grober, E.3    Najari, B.B.4    Murthy, L.5    Lamb, D.J.6
  • 39
    • 59349098253 scopus 로고    scopus 로고
    • Outcomes analysis of testosterone supplementation in hypogonadal men following radical prostatectomy
    • abstract 1181
    • O. Nabulsi, R. Tal, G. Gotto, J. Narus, L. Goldenberg, J.P. Mulhall Outcomes analysis of testosterone supplementation in hypogonadal men following radical prostatectomy J Urol 179 suppl 2008 406 abstract 1181
    • (2008) J Urol , vol.179 , Issue.SUPPL. , pp. 406
    • Nabulsi, O.1    Tal, R.2    Gotto, G.3    Narus, J.4    Goldenberg, L.5    Mulhall, J.P.6
  • 40
    • 59349090198 scopus 로고    scopus 로고
    • Analysis of the PSA response after testosterone supplementation in patients who have previously received management for their localized prostate cancer
    • abstract 1247
    • H.H. Davila, C.N. Arison, M.K. Hall, R. Salup, J.L. Lockhart, R.E. Carrion Analysis of the PSA response after testosterone supplementation in patients who have previously received management for their localized prostate cancer J Urol 179 suppl 2008 428 abstract 1247
    • (2008) J Urol , vol.179 , Issue.SUPPL. , pp. 428
    • Davila, H.H.1    Arison, C.N.2    Hall, M.K.3    Salup, R.4    Lockhart, J.L.5    Carrion, R.E.6
  • 41
    • 0029555980 scopus 로고
    • Changes in serum levels of prostatic acid phosphatase and prostate specific antigen after luteinizing hormone-releasing hormone analogue administration in patients with metastatic prostatic cancer in relation to glandular differentiation
    • I. Sasagawa, T. Nakada, Y. Kubota, T. Sawamura, K. Izumiya Changes in serum levels of prostatic acid phosphatase and prostate specific antigen after luteinizing hormone-releasing hormone analogue administration in patients with metastatic prostatic cancer in relation to glandular differentiation Int Urol Nephrol 27 1995 769
    • (1995) Int Urol Nephrol , vol.27 , pp. 769
    • Sasagawa, I.1    Nakada, T.2    Kubota, Y.3    Sawamura, T.4    Izumiya, K.5
  • 42
    • 33845329200 scopus 로고    scopus 로고
    • Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen of 4.0 ng/ml or less
    • A. Morgentaler, E.L. Rhoden Prevalence of prostate cancer among hypogonadal men with prostate-specific antigen of 4.0 ng/ml or less Urology 68 2006 1263
    • (2006) Urology , vol.68 , pp. 1263
    • Morgentaler, A.1    Rhoden, E.L.2
  • 43
    • 33750978404 scopus 로고    scopus 로고
    • Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: A randomized controlled trial
    • L.S. Marks, N.A. Mazer, E. Mostaghel, D.L. Hess, F.J. Dorey, J.I. Epstein Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial JAMA 296 2006 2351
    • (2006) JAMA , vol.296 , pp. 2351
    • Marks, L.S.1    Mazer, N.A.2    Mostaghel, E.3    Hess, D.L.4    Dorey, F.J.5    Epstein, J.I.6
  • 44
    • 59349097507 scopus 로고    scopus 로고
    • A single institution experience with biochemical recurrence after radical prostatectomy for tumors that on pathology are of small volume or "insignificant."
    • Epub ahead of print
    • I.M. van Oort, D.E. Kok, L.A. Kiemeney, C.A. Hulsbergen-van de Kaa, J.A. Witjes A single institution experience with biochemical recurrence after radical prostatectomy for tumors that on pathology are of small volume or "insignificant." Urol Oncol 2008 Epub ahead of print
    • (2008) Urol Oncol
    • Van Oort, I.M.1    Kok, D.E.2    Kiemeney, L.A.3    Hulsbergen-Van De Kaa, C.A.4    Witjes, J.A.5
  • 45
    • 0242692553 scopus 로고    scopus 로고
    • Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: Results of 1 year of treatment in men with prostatic intraepithelial neoplasia
    • E.L. Rhoden, A. Morgentaler Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia J Urol 170 2003 2348
    • (2003) J Urol , vol.170 , pp. 2348
    • Rhoden, E.L.1    Morgentaler, A.2
  • 46
    • 0029856354 scopus 로고    scopus 로고
    • Incidence of occult prostate cancer among men with low total or free serum testosterone
    • A. Morgentaler, C.O. Bruning 3rd, W.C. DeWolf Incidence of occult prostate cancer among men with low total or free serum testosterone JAMA 276 1996 1904
    • (1996) JAMA , vol.276 , pp. 1904
    • Morgentaler, A.1    Bruning III, C.O.2    Dewolf, W.C.3
  • 47
    • 16844385404 scopus 로고    scopus 로고
    • Androgen causes growth suppression and reversion of androgen-independent prostate cancer xenografts to an androgen-stimulated phenotype in athymic mice
    • C.P. Chuu, R.A. Hiipakka, J. Fukuchi, J.M. Kokontis, S. Liao Androgen causes growth suppression and reversion of androgen-independent prostate cancer xenografts to an androgen-stimulated phenotype in athymic mice Cancer Res 65 2005 2082
    • (2005) Cancer Res , vol.65 , pp. 2082
    • Chuu, C.P.1    Hiipakka, R.A.2    Fukuchi, J.3    Kokontis, J.M.4    Liao, S.5
  • 48
    • 43049112754 scopus 로고    scopus 로고
    • Change in prostate specific antigen following androgen stimulation is an independent predictor of prostate cancer diagnosis
    • R.S. Svatek, M.J. Shulman, E.A. Benaim, T.E. Rogers, V. Margulis Change in prostate specific antigen following androgen stimulation is an independent predictor of prostate cancer diagnosis J Urol 179 2008 2192
    • (2008) J Urol , vol.179 , pp. 2192
    • Svatek, R.S.1    Shulman, M.J.2    Benaim, E.A.3    Rogers, T.E.4    Margulis, V.5


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