메뉴 건너뛰기




Volumn 96, Issue 2, 2011, Pages 430-437

Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: A randomized-controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANOLONE; PLACEBO; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE;

EID: 79951714359     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-1865     Document Type: Article
Times cited : (64)

References (36)
  • 2
    • 0035097033 scopus 로고    scopus 로고
    • Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
    • Harman SM, Metter EJ, Tobin JD, Pearson J, Blackman MR 2001 Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 86:724-731
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 724-731
    • Harman, S.M.1    Metter, E.J.2    Tobin, J.D.3    Pearson, J.4    Blackman, M.R.5
  • 3
    • 0028358995 scopus 로고
    • Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls
    • Behre HM, Bohmeyer J, Nieschlag E 1994 Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls. Clin Endocrinol (Oxf) 40:341-349 (Pubitemid 24194627)
    • (1994) Clinical Endocrinology , vol.40 , Issue.3 , pp. 341-349
    • Behre, H.M.1    Bohmeyer, J.2    Nieschlag, E.3
  • 4
    • 39149084101 scopus 로고    scopus 로고
    • Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies
    • DOI 10.1093/jnci/djm323
    • Roddam AW, Allen NE, Appleby P, Key TJ 2008 Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies. J Natl Cancer Inst 100:170-183 (Pubitemid 351480553)
    • (2008) Journal of the National Cancer Institute , vol.100 , Issue.3 , pp. 170-183
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3    Key, T.J.4
  • 9
    • 0035528888 scopus 로고    scopus 로고
    • The role of 5alpha-reduction in steroid hormone physiology
    • Wilson JD 2001 The role of 5alpha-reduction in steroid hormone physiology. Reprod Fertil Dev 13:673-678 (Pubitemid 34240215)
    • (2001) Reproduction, Fertility and Development , vol.13 , Issue.7-8 , pp. 673-678
    • Wilson, J.D.1
  • 12
    • 0027767192 scopus 로고
    • Androgen metabolism in men receiving finasteride before prostatectomy
    • Norman RW, Coakes KE, Wright AS, Rittmaster RS 1993 Androgen metabolism in men receiving finasteride before prostatectomy. J Urol 150:1736-1739 (Pubitemid 24346938)
    • (1993) Journal of Urology , vol.150 , Issue.5 II , pp. 1736-1739
    • Norman, R.W.1    Coakes, K.E.2    Wright, A.S.3    Rittmaster, R.S.4
  • 13
    • 52949132642 scopus 로고    scopus 로고
    • Effect of dutasteride on intraprostatic androgen levels in men with benign prostatic hyperplasia or prostate cancer
    • Rittmaster R, Hahn RG, Ray P, Shannon JB, Wurzel R 2008 Effect of dutasteride on intraprostatic androgen levels in men with benign prostatic hyperplasia or prostate cancer. Urology 72:808-812
    • (2008) Urology , vol.72 , pp. 808-812
    • Rittmaster, R.1    Hahn, R.G.2    Ray, P.3    Shannon, J.B.4    Wurzel, R.5
  • 16
    • 0034847204 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency
    • DOI 10.1210/jc.86.9.4078
    • Ly LP, Jimenez M, Zhuang TN, Celermajer DS, Conway AJ, Handelsman DJ 2001 A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency. J Clin Endocrinol Metab 86:4078-4088 (Pubitemid 32848516)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.9 , pp. 4078-4088
    • Ly, L.P.1    Jimenez, M.2    Zhuang, T.N.3    Celermajer, D.S.4    Conway, A.J.5    Handelsman, D.J.6
  • 17
    • 0032454317 scopus 로고    scopus 로고
    • Dihydrotestosterone: A rationale for its use as a non-aromatizable androgen replacement therapeutic agent
    • Swerdloff RS, Wang C 1998 Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillieres Clin Endocrinol Metab 12:501-506
    • (1998) Baillieres Clin Endocrinol Metab , vol.12 , pp. 501-506
    • Swerdloff, R.S.1    Wang, C.2
  • 19
    • 0026591918 scopus 로고
    • The American Urological Association symptom index for benign prostatic hyperplasia
    • The Measurement Committee of the American Urological Association
    • Barry MJ, Fowler Jr FJ, O'Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK, Cockett AT 1992 The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol 148:1549-1557
    • (1992) J Urol , vol.148 , pp. 1549-1557
    • Barry, M.J.1    Fowler Jr., F.J.2    O'Leary, M.P.3    Bruskewitz, R.C.4    Holtgrewe, H.L.5    Mebust, W.K.6    Cockett, A.T.7
  • 22
    • 76749096777 scopus 로고    scopus 로고
    • Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: Implications for prostate cancer chemoprevention
    • Mostaghel EA, Geng L, Holcomb I, Coleman IM, Lucas J, True LD, Nelson PS Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention. Cancer Res 70:1286-1295
    • Cancer Res , vol.70 , pp. 1286-1295
    • Mostaghel, E.A.1    Geng, L.2    Holcomb, I.3    Coleman, I.M.4    Lucas, J.5    True, L.D.6    Nelson, P.S.7
  • 24
    • 77953390474 scopus 로고    scopus 로고
    • Oxidative DNA damage in the prostate may predispose men to a higher risk of prostate cancer
    • Wu JD, Lin DW, Page ST, Lundgren AD, True LD, Plymate SR 2009 Oxidative DNA damage in the prostate may predispose men to a higher risk of prostate cancer. Transl Oncol 2:39-45
    • (2009) Transl Oncol , vol.2 , pp. 39-45
    • Wu, J.D.1    Lin, D.W.2    Page, S.T.3    Lundgren, A.D.4    True, L.D.5    Plymate, S.R.6
  • 25
    • 0026583498 scopus 로고
    • Effects of rectal examination, prostatic massage, ultrasonography and needle biopsy on serum prostate specific antigen levels
    • Yuan JJ, Coplen DE, Petros JA, Figenshau RS, Ratliff TL, Smith DS, Catalona WJ 1992 Effects of rectal examination, prostatic massage, ultrasonography and needle biopsy on serum prostate specific antigen levels. J Urol 147:810-814
    • (1992) J Urol , vol.147 , pp. 810-814
    • Yuan, J.J.1    Coplen, D.E.2    Petros, J.A.3    Figenshau, R.S.4    Ratliff, T.L.5    Smith, D.S.6    Catalona, W.J.7
  • 29
    • 33947216862 scopus 로고    scopus 로고
    • The effect of food composition on serum testosterone levels after oral administration of Andriol Testocaps
    • DOI 10.1111/j.1365-2265.2007.02781.x
    • Schnabel PG, Bagchus W, Lass H, Thomsen T, Geurts TB 2007 The effect of food composition on serum testosterone levels after oral administration of Andriol Testocaps. Clin Endocrinol (Oxf) 66:579-585 (Pubitemid 46434947)
    • (2007) Clinical Endocrinology , vol.66 , Issue.4 , pp. 579-585
    • Schnabel, P.G.1    Bagchus, W.2    Lass, H.3    Thomsen, T.4    Geurts, T.B.P.5
  • 30
    • 65549104191 scopus 로고    scopus 로고
    • Oral testosterone replacement in symptomatic late-onset hypogonadism: Effects on rating scales and general safety in a randomized, placebo-controlled study
    • Legros JJ, Meuleman EJ, Elbers JM, Geurts TB, Kaspers MJ, Bouloux PM 2009 Oral testosterone replacement in symptomatic late-onset hypogonadism: effects on rating scales and general safety in a randomized, placebo-controlled study. Eur J Endocrinol 160:821-831
    • (2009) Eur J Endocrinol , vol.160 , pp. 821-831
    • Legros, J.J.1    Meuleman, E.J.2    Elbers, J.M.3    Geurts, T.B.4    Kaspers, M.J.5    Bouloux, P.M.6
  • 32
    • 48349145200 scopus 로고    scopus 로고
    • Prostate tissue androgens: History and current clinical relevance
    • Marks LS, Mostaghel EA, Nelson PS 2008 Prostate tissue androgens: history and current clinical relevance. Urology 72:247-254
    • (2008) Urology , vol.72 , pp. 247-254
    • Marks, L.S.1    Mostaghel, E.A.2    Nelson, P.S.3
  • 35
    • 61749095503 scopus 로고    scopus 로고
    • The dual, opposing roles of estrogen in the prostate
    • Ellem SJ, Risbridger GP 2009 The dual, opposing roles of estrogen in the prostate. Ann NY Acad Sci 1155:174-186
    • (2009) Ann NY Acad Sci , vol.1155 , pp. 174-186
    • Ellem, S.J.1    Risbridger, G.P.2
  • 36
    • 73249124203 scopus 로고    scopus 로고
    • Effects of aromatase inhibition on bone mineral density and bone turnover in older men with low testosterone levels
    • Burnett-Bowie SA, McKay EA, Lee H, Leder BZ 2009 Effects of aromatase inhibition on bone mineral density and bone turnover in older men with low testosterone levels. J Clin Endocrinol Metab 94:4785-4792
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4785-4792
    • Burnett-Bowie, S.A.1    McKay, E.A.2    Lee, H.3    Leder, B.Z.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.