-
1
-
-
0033103644
-
Oxidative DNA damage, antioxidants, and cancer
-
Collins, A. R. (1999) Oxidative DNA damage, antioxidants, and cancer. BioEssays 21, 238-246
-
(1999)
BioEssays
, vol.21
, pp. 238-246
-
-
Collins, A.R.1
-
2
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman, C., Stephens, P., Smith, R., Dalgliesh, G. L., Hunter, C., Bignell, G., Davies, H., Teague, J., Butler, A., Stevens, C., Edkins, S., O'Meara, S., Vastrik, I., Schmidt, E. E., Avis, T., Barthorpe, S., Bhamra, G., Buck, G., Choudhury, B., Clements, J., Cole, J., Dicks, E., Forbes, S., Gray, K., Halliday, K., Harrison, R., Hills, K., Hinton, J., Jenkinson, A., Jones, D., Menzies, A., Mironenko, T., Perry, J., Raine, K., Richardson, D., Shepherd, R., Small, A., Tofts, C., Varian, J., Webb, T., West, S., Widaa, S., Yates, A., Cahill, D. P., Louis, D. N., Goldstraw, P., Nicholson, A. G., Brasseur, F., Looijenga, L., Weber, B. L., Chiew, Y. E., DeFazio, A., Greaves, M. F., Green, A. R., Campbell, P., Birney, E., Easton, D. F., Chenevix-Trench, G., Tan, M. H., Khoo, S. K., Teh, B. T., Yuen, S. T., Leung, S. Y., Wooster, R., Futreal, P. A., and Stratton, M. R. (2007) Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
Edkins, S.11
O'meara, S.12
Vastrik, I.13
Schmidt, E.E.14
Avis, T.15
Barthorpe, S.16
Bhamra, G.17
Buck, G.18
Choudhury, B.19
Clements, J.20
Cole, J.21
Dicks, E.22
Forbes, S.23
Gray, K.24
Halliday, K.25
Harrison, R.26
Hills, K.27
Hinton, J.28
Jenkinson, A.29
Jones, D.30
Menzies, A.31
Mironenko, T.32
Perry, J.33
Raine, K.34
Richardson, D.35
Shepherd, R.36
Small, A.37
Tofts, C.38
Varian, J.39
Webb, T.40
West, S.41
Widaa, S.42
Yates, A.43
Cahill, D.P.44
Louis, D.N.45
Goldstraw, P.46
Nicholson, A.G.47
Brasseur, F.48
Looijenga, L.49
Weber, B.L.50
Chiew, Y.E.51
Defazio, A.52
Greaves, M.F.53
Green, A.R.54
Campbell, P.55
Birney, E.56
Easton, D.F.57
Chenevix-Trench, G.58
Tan, M.H.59
Khoo, S.K.60
Teh, B.T.61
Yuen, S.T.62
Leung, S.Y.63
Wooster, R.64
Futreal, P.A.65
Stratton, M.R.66
more..
-
3
-
-
58549088129
-
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair
-
Maga, G., Crespan, E., Wimmer, U., van Loon, B., Amoroso, A., Mondello, C., Belgiovine, C., Ferrari, E., Locatelli, G., Villani, G., and Hübscher, U. (2008) Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. Proc. Natl. Acad. Sci. U.S.A. 105, 20689-20694
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 20689-20694
-
-
Maga, G.1
Crespan, E.2
Wimmer, U.3
Van Loon, B.4
Amoroso, A.5
Mondello, C.6
Belgiovine, C.7
Ferrari, E.8
Locatelli, G.9
Villani, G.10
Hübscher, U.11
-
4
-
-
34249870372
-
8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins
-
Maga, G., Villani, G., Crespan, E., Wimmer, U., Ferrari, E., Bertocci, B., and Hübscher, U. (2007) 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. Nature 447, 606-608
-
(2007)
Nature
, vol.447
, pp. 606-608
-
-
Maga, G.1
Villani, G.2
Crespan, E.3
Wimmer, U.4
Ferrari, E.5
Bertocci, B.6
Hübscher, U.7
-
5
-
-
24744472268
-
DNA polymerase protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/ repair
-
Braithwaite, E. K., Kedar, P. S., Lan, L., Polosina, Y. Y., Asagoshi, K., Poltoratsky, V. P., Horton, J. K., Miller, H., Teebor, G. W., Yasui, A., and Wilson, S. H. (2005) DNA polymerase protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/ repair. J. Biol. Chem. 280, 31641-31647
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31641-31647
-
-
Braithwaite, E.K.1
Kedar, P.S.2
Lan, L.3
Polosina, Y.Y.4
Asagoshi, K.5
Poltoratsky, V.P.6
Horton, J.K.7
Miller, H.8
Teebor, G.W.9
Yasui, A.10
Wilson, S.H.11
-
6
-
-
0141532257
-
Mutator phenotype of MUTYH-null mouse embryonic stem cells
-
Hirano, S., Tominaga, Y., Ichinoe, A., Ushijima, Y., Tsuchimoto, D., Honda-Ohnishi, Y., Ohtsubo, T., Sakumi, K., and Nakabeppu, Y. (2003) Mutator phenotype of MUTYH-null mouse embryonic stem cells. J. Biol. Chem. 278, 38121-38124
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38121-38124
-
-
Hirano, S.1
Tominaga, Y.2
Ichinoe, A.3
Ushijima, Y.4
Tsuchimoto, D.5
Honda-Ohnishi, Y.6
Ohtsubo, T.7
Sakumi, K.8
Nakabeppu, Y.9
-
7
-
-
66249146924
-
Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis
-
Russo, M. T., De Luca, G., Casorelli, I., Degan, P., Molatore, S., Barone, F., Mazzei, F., Pannellini, T., Musiani, P., and Bignami, M. (2009) Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis. Cancer Res. 69, 4372-4379
-
(2009)
Cancer Res.
, vol.69
, pp. 4372-4379
-
-
Russo, M.T.1
De Luca, G.2
Casorelli, I.3
Degan, P.4
Molatore, S.5
Barone, F.6
Mazzei, F.7
Pannellini, T.8
Musiani, P.9
Bignami, M.10
-
8
-
-
34547105083
-
MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis
-
Sakamoto, K., Tominaga, Y., Yamauchi, K., Nakatsu, Y., Sakumi, K., Yoshiyama, K., Egashira, A., Kura, S., Yao, T., Tsuneyoshi, M., Maki, H., Nakabeppu, Y., and Tsuzuki, T. (2007) MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis. Cancer Res. 67, 6599-6604
-
(2007)
Cancer Res.
, vol.67
, pp. 6599-6604
-
-
Sakamoto, K.1
Tominaga, Y.2
Yamauchi, K.3
Nakatsu, Y.4
Sakumi, K.5
Yoshiyama, K.6
Egashira, A.7
Kura, S.8
Yao, T.9
Tsuneyoshi, M.10
Maki, H.11
Nakabeppu, Y.12
Tsuzuki, T.13
-
9
-
-
80054773609
-
Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer
-
Shinmura, K., Goto, M., Suzuki, M., Tao, H., Yamada, H., Igarashi, H., Matsuura, S., Maeda, M., Konno, H., Matsuda, T., and Sugimura, H. (2011) Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer. J. Pathol. 225, 414-423
-
(2011)
J. Pathol.
, vol.225
, pp. 414-423
-
-
Shinmura, K.1
Goto, M.2
Suzuki, M.3
Tao, H.4
Yamada, H.5
Igarashi, H.6
Matsuura, S.7
Maeda, M.8
Konno, H.9
Matsuda, T.10
Sugimura, H.11
-
10
-
-
0037115397
-
8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells
-
Parker, A. R., O'Meally, R. N., Oliver, D. H., Hua, L., Nelson, W. G., DeWeese, T. L., and Eshleman, J. R. (2002) 8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells. Cancer Res. 62, 7230-7233
-
(2002)
Cancer Res.
, vol.62
, pp. 7230-7233
-
-
Parker, A.R.1
O'meally, R.N.2
Oliver, D.H.3
Hua, L.4
Nelson, W.G.5
Deweese, T.L.6
Eshleman, J.R.7
-
11
-
-
84873696103
-
USP7S-dependent inactivation of Mule regulatesDNAdamage signalling and repair
-
Khoronenkova, S. V., and Dianov, G. L. (2013) USP7S-dependent inactivation of Mule regulatesDNAdamage signalling and repair. Nucleic Acids Res. 41, 1750-1756
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 1750-1756
-
-
Khoronenkova, S.V.1
Dianov, G.L.2
-
12
-
-
84855984709
-
Regulation of oxidative DNA damage repair by DNA polymerase and MutYH by cross-talk of phosphorylation and ubiquitination
-
Markkanen, E., van Loon, B., Ferrari, E., Parsons, J. L., Dianov, G. L., and Hübscher, U. (2012) Regulation of oxidative DNA damage repair by DNA polymerase and MutYH by cross-talk of phosphorylation and ubiquitination. Proc. Natl. Acad. Sci. U.S.A. 109, 437-442
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 437-442
-
-
Markkanen, E.1
Van Loon, B.2
Ferrari, E.3
Parsons, J.L.4
Dianov, G.L.5
Hübscher, U.6
-
13
-
-
39549106043
-
CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins
-
Parsons, J. L., Tait, P. S., Finch, D., Dianova, I. I., Allinson, S. L., and Dianov, G. L. (2008) CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins. Mol. Cell 29, 477-487
-
(2008)
Mol. Cell
, vol.29
, pp. 477-487
-
-
Parsons, J.L.1
Tait, P.S.2
Finch, D.3
Dianova, I.I.4
Allinson, S.L.5
Dianov, G.L.6
-
14
-
-
70350340291
-
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
-
Parsons, J. L., Tait, P. S., Finch, D., Dianova, I. I., Edelmann, M. J., Khoronenkova, S. V., Kessler, B. M., Sharma, R. A., McKenna, W. G., and Dianov, G. L. (2009) Ubiquitin ligase ARF-BP1/Mule modulates base excision repair. EMBO J. 28, 3207-3215
-
(2009)
EMBO J.
, vol.28
, pp. 3207-3215
-
-
Parsons, J.L.1
Tait, P.S.2
Finch, D.3
Dianova, I.I.4
Edelmann, M.J.5
Khoronenkova, S.V.6
Kessler, B.M.7
Sharma, R.A.8
McKenna, W.G.9
Dianov, G.L.10
-
15
-
-
0035393812
-
HMYH cell cycle-dependent expression, subcellular localization and association with replication foci: Evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs
-
Boldogh, I., Milligan, D., Lee, M. S., Bassett, H., Lloyd, R. S., and Mc-Cullough, A. K. (2001) hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs. Nucleic Acids Res. 29, 2802-2809
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2802-2809
-
-
Boldogh, I.1
Milligan, D.2
Lee, M.S.3
Bassett, H.4
Lloyd, R.S.5
Mc-Cullough, A.K.6
-
16
-
-
70849113575
-
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda
-
van Loon, B., and Hübscher, U. (2009) An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda. Proc. Natl. Acad. Sci. U.S.A. 106, 18201-18206
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 18201-18206
-
-
Van Loon, B.1
Hübscher, U.2
-
17
-
-
33749483796
-
A human cell-based assay to evaluate the effects of alterations in the MLH1 mismatch repair gene
-
Blasi, M. F., Ventura, I., Aquilina, G., Degan, P., Bertario, L., Bassi, C., Radice, P., and Bignami, M. (2006) A human cell-based assay to evaluate the effects of alterations in the MLH1 mismatch repair gene. Cancer Res. 66, 9036-9044
-
(2006)
Cancer Res.
, vol.66
, pp. 9036-9044
-
-
Blasi, M.F.1
Ventura, I.2
Aquilina, G.3
Degan, P.4
Bertario, L.5
Bassi, C.6
Radice, P.7
Bignami, M.8
-
18
-
-
18144381942
-
Degradation of human exonuclease 1b upon DNA synthesis inhibition
-
El-Shemerly, M., Janscak, P., Hess, D., Jiricny, J., and Ferrari, S. (2005) Degradation of human exonuclease 1b upon DNA synthesis inhibition. Cancer Res. 65, 3604-3609
-
(2005)
Cancer Res.
, vol.65
, pp. 3604-3609
-
-
El-Shemerly, M.1
Janscak, P.2
Hess, D.3
Jiricny, J.4
Ferrari, S.5
-
19
-
-
50349091399
-
Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry
-
Taghizadeh, K., McFaline, J. L., Pang, B., Sullivan, M., Dong, M., Plummer, E., and Dedon, P. C. (2008) Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry. Nat. Protoc. 3, 1287-1298
-
(2008)
Nat. Protoc.
, vol.3
, pp. 1287-1298
-
-
Taghizadeh, K.1
McFaline, J.L.2
Pang, B.3
Sullivan, M.4
Dong, M.5
Plummer, E.6
Dedon, P.C.7
-
20
-
-
84859111172
-
ATM-dependent down-regulation of USP7/ HAUSP by PPM1G activates p53 response to DNA damage
-
Khoronenkova, S. V., Dianova, I. I., Ternette, N., Kessler, B. M., Parsons, J. L., and Dianov, G. L. (2012) ATM-dependent down-regulation of USP7/ HAUSP by PPM1G activates p53 response to DNA damage. Mol. Cell 45, 801-813
-
(2012)
Mol. Cell
, vol.45
, pp. 801-813
-
-
Khoronenkova, S.V.1
Dianova, I.I.2
Ternette, N.3
Kessler, B.M.4
Parsons, J.L.5
Dianov, G.L.6
-
21
-
-
21244451434
-
ARF-BP1/ Mule is a critical mediator of the ARF tumor suppressor
-
Chen, D., Kon, N., Li, M., Zhang, W., Qin, J., and Gu, W. (2005) ARF-BP1/ Mule is a critical mediator of the ARF tumor suppressor. Cell 121, 1071-1083
-
(2005)
Cell
, vol.121
, pp. 1071-1083
-
-
Chen, D.1
Kon, N.2
Li, M.3
Zhang, W.4
Qin, J.5
Gu, W.6
-
22
-
-
33847401446
-
Regulation of p53 localization and transcription by theHECTdomain E3 ligaseWWP1
-
Laine, A., and Ronai, Z. (2007) Regulation of p53 localization and transcription by theHECTdomain E3 ligaseWWP1.Oncogene 26, 1477-1483
-
(2007)
Oncogene
, vol.26
, pp. 1477-1483
-
-
Laine, A.1
Ronai, Z.2
-
23
-
-
3042739635
-
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumorprone mice defective in both theMyhand Ogg1DNAglycosylases
-
Russo, M. T., De Luca, G., Degan, P., Parlanti, E., Dogliotti, E., Barnes, D. E., Lindahl, T., Yang, H., Miller, J. H., and Bignami, M. (2004) Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumorprone mice defective in both theMyhand Ogg1DNAglycosylases. Cancer Res. 64, 4411-4414
-
(2004)
Cancer Res.
, vol.64
, pp. 4411-4414
-
-
Russo, M.T.1
De Luca, G.2
Degan, P.3
Parlanti, E.4
Dogliotti, E.5
Barnes, D.E.6
Lindahl, T.7
Yang, H.8
Miller, J.H.9
Bignami, M.10
-
24
-
-
2342520175
-
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
-
Xie, Y., Yang, H., Cunanan, C., Okamoto, K., Shibata, D., Pan, J., Barnes, D. E., Lindahl, T., McIlhatton, M., Fishel, R., and Miller, J. H. (2004) Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res. 64, 3096-3102
-
(2004)
Cancer Res.
, vol.64
, pp. 3096-3102
-
-
Xie, Y.1
Yang, H.2
Cunanan, C.3
Okamoto, K.4
Shibata, D.5
Pan, J.6
Barnes, D.E.7
Lindahl, T.8
McIlhatton, M.9
Fishel, R.10
Miller, J.H.11
-
25
-
-
0004228157
-
-
2nd Ed., ASM Press, Washington, D. C
-
Friedberg, E., Walker, G., and Siede, W. (2006)DNARepair and Mutagenesis, 2nd Ed., p. 16, ASM Press, Washington, D. C.
-
(2006)
DNA Repair and Mutagenesis
, pp. 16
-
-
Friedberg, E.1
Walker, G.2
Siede, W.3
-
26
-
-
84876187912
-
MUTYH DNA glycosylase: The rationale for removing undamaged bases from the DNA
-
Markkanen, E., Dorn, J., and Hübscher, U. (2013) MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA. Front. Genet. 4, 18
-
(2013)
Front. Genet.
, vol.4
, pp. 18
-
-
Markkanen, E.1
Dorn, J.2
Hübscher, U.3
-
27
-
-
0033568099
-
Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase
-
Takao, M., Zhang, Q. M., Yonei, S., and Yasui, A. (1999) Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase. Nucleic Acids Res. 27, 3638-3644
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 3638-3644
-
-
Takao, M.1
Zhang, Q.M.2
Yonei, S.3
Yasui, A.4
-
28
-
-
53249097348
-
Control of DNA polymerase stability by phosphorylation and ubiquitination during the cell cycle
-
Wimmer, U., Ferrari, E., Hunziker, P., and Hübscher, U. (2008) Control of DNA polymerase stability by phosphorylation and ubiquitination during the cell cycle. EMBO Rep. 9, 1027-1033
-
(2008)
EMBO Rep.
, vol.9
, pp. 1027-1033
-
-
Wimmer, U.1
Ferrari, E.2
Hunziker, P.3
Hübscher, U.4
-
29
-
-
24944591014
-
Phosphorylation of human DNA polymerase by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen
-
Frouin, I., Toueille, M., Ferrari, E., Shevelev, I., and Hübscher, U. (2005) Phosphorylation of human DNA polymerase by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen. Nucleic Acids Res. 33, 5354-5361
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5354-5361
-
-
Frouin, I.1
Toueille, M.2
Ferrari, E.3
Shevelev, I.4
Hübscher, U.5
-
30
-
-
84884588531
-
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability
-
Ruggieri, V., Pin, E., Russo, M. T., Barone, F., Degan, P., Sanchez, M., Quaia, M., Minoprio, A., Turco, E., Mazzei, F., Viel, A., and Bignami, M. (2013) Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability. Oncogene 32, 4500-4508
-
(2013)
Oncogene
, vol.32
, pp. 4500-4508
-
-
Ruggieri, V.1
Pin, E.2
Russo, M.T.3
Barone, F.4
Degan, P.5
Sanchez, M.6
Quaia, M.7
Minoprio, A.8
Turco, E.9
Mazzei, F.10
Viel, A.11
Bignami, M.12
-
31
-
-
84891163582
-
Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage
-
Hwang, B. J., Shi, G., and Lu, A. L. (2014) Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage. DNA Repair 13, 10-21
-
(2014)
DNA Repair
, vol.13
, pp. 10-21
-
-
Hwang, B.J.1
Shi, G.2
Lu, A.L.3
|