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Volumn 8, Issue 11, 2013, Pages

The zinc transporter Zip5 ( Slc39a5) regulates intestinal zinc excretion and protects the pancreas against zinc toxicity

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN ZIP4; PROTEIN ZIP5; SECRETORY PROTEIN; UNCLASSIFIED DRUG; ZINC; ZINC TRANSPORTER;

EID: 84896740557     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082149     Document Type: Article
Times cited : (51)

References (61)
  • 1
    • 84881507393 scopus 로고    scopus 로고
    • Zinc and the zinc proteome
    • Maret W (2013) Zinc and the zinc proteome. Met Ions Life Sci 12: 479-501.
    • (2013) Met Ions Life Sci , vol.12 , pp. 479-501
    • Maret, W.1
  • 2
    • 79959997623 scopus 로고    scopus 로고
    • Metals on the move: Zinc ions in cellular regulation and in the coordination dynamics of zinc proteins
    • Maret W (2011) Metals on the move: zinc ions in cellular regulation and in the coordination dynamics of zinc proteins. Biometals 24: 411-418.
    • (2011) Biometals , vol.24 , pp. 411-418
    • Maret, W.1
  • 3
    • 84867152630 scopus 로고    scopus 로고
    • Molecular architecture and function of ZnT transporters
    • Kambe T (2012) Molecular architecture and function of ZnT transporters. Curr Top Membr 69: 199-220.
    • (2012) Curr Top Membr , vol.69 , pp. 199-220
    • Kambe, T.1
  • 5
    • 84875129764 scopus 로고    scopus 로고
    • The SLC39 family of zinc transporters
    • Jeong J, Eide DJ (2013) The SLC39 family of zinc transporters. Mol Aspects Med 34: 612-619.
    • (2013) Mol Aspects Med , vol.34 , pp. 612-619
    • Jeong, J.1    Eide, D.J.2
  • 6
    • 84875196486 scopus 로고    scopus 로고
    • The SLC30 family of zinc transporters - A review of current understanding of their biological and pathophysiological roles
    • Huang L, Tepaamorndech S (2013) The SLC30 family of zinc transporters - A review of current understanding of their biological and pathophysiological roles. Mol Aspects Med 34: 548-560.
    • (2013) Mol Aspects Med , vol.34 , pp. 548-560
    • Huang, L.1    Tepaamorndech, S.2
  • 7
    • 0029985755 scopus 로고    scopus 로고
    • Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency
    • Dalton TP, Fu K, Palmiter RD, Andrews GK (1996) Transgenic mice that over-express metallothionein-I resist dietary zinc deficiency. J Nutr 126: 825-833. (Pubitemid 26100951)
    • (1996) Journal of Nutrition , vol.126 , Issue.4 , pp. 825-833
    • Dalton, T.1    Fu, K.2    Palmiter, R.D.3    Andrews, G.K.4
  • 8
    • 0032839870 scopus 로고    scopus 로고
    • Expression of the mouse metallothionein-I and -II genes provides a reproductive advantage during maternal dietary zinc deficiency
    • Andrews GK, Geiser J (1999) Expression of metallothionein-I and -II genes provides a reproductive advantage during maternal dietary zinc deficiency. J Nutr 129: 1643-1648. (Pubitemid 29406615)
    • (1999) Journal of Nutrition , vol.129 , Issue.9 , pp. 1643-1648
    • Andrews, G.K.1    Geiser, J.2
  • 9
    • 84867146865 scopus 로고    scopus 로고
    • The cation selectivity of the ZIP transporters
    • Dempski RE (2012) The cation selectivity of the ZIP transporters. Curr Top Membr 69: 221-245.
    • (2012) Curr Top Membr , vol.69 , pp. 221-245
    • Dempski, R.E.1
  • 11
    • 80053210392 scopus 로고    scopus 로고
    • Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron
    • Pinilla-Tenas JJ, Sparkman BK, Shawki A, Illing AC, Mitchell CJ et al. (2011) Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron. Am J Physiol Cell Physiol 301: C862-C871
    • (2011) Am J Physiol Cell Physiol , vol.301
    • Pinilla-Tenas, J.J.1    Sparkman, B.K.2    Shawki, A.3    Illing, A.C.4    Mitchell, C.J.5
  • 12
    • 45549087856 scopus 로고    scopus 로고
    • Slc39a1 to 3 (subfamily II) Zip genes in mice have unique cell-specific functions during adaptation to zinc deficiency
    • Kambe T, Geiser J, Lahner B, Salt DE, Andrews GK (2008) Slc39a1 to 3 (subfamily II) Zip genes in mice have unique cell-specific functions during adaptation to zinc deficiency. Am J Physiol Regul Integr Comp Physiol 294: R1474-R1481
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Kambe, T.1    Geiser, J.2    Lahner, B.3    Salt, D.E.4    Andrews, G.K.5
  • 13
    • 84858074257 scopus 로고    scopus 로고
    • Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease
    • Quadri M, Federico A, Zhao T, Breedveld GJ, Battisti C et al. (2012) Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease. Am J Hum Genet 90: 467-477.
    • (2012) Am J Hum Genet , vol.90 , pp. 467-477
    • Quadri, M.1    Federico, A.2    Zhao, T.3    Breedveld, G.J.4    Battisti, C.5
  • 14
    • 84880953917 scopus 로고    scopus 로고
    • Rat pancreatitis produced by 13-week administration of zinc oxide nanoparticles: Biopersistence of nanoparticles and possible solutions
    • Seok SH, Cho WS, Park JS, Na Y, Jang A et al. (2013) Rat pancreatitis produced by 13-week administration of zinc oxide nanoparticles: biopersistence of nanoparticles and possible solutions. J Appl Toxicol 33: 1089-1096.
    • (2013) J Appl Toxicol , vol.33 , pp. 1089-1096
    • Seok, S.H.1    Cho, W.S.2    Park, J.S.3    Na, Y.4    Jang, A.5
  • 16
    • 34347352057 scopus 로고    scopus 로고
    • The mouse acrodermatitis enteropathica gene Slc39a4 (Zip4) is essential for early development and heterozygosity causes hypersensitivity to zinc deficiency
    • DOI 10.1093/hmg/ddm088
    • Dufner-Beattie J, Weaver BP, Geiser J, Bilgen M, Larson M et al. (2007) The mouse acrodermatitis gene Slc39a4 (ZIP4) is essential for development and heterozygosity causes hypersensitivity to zinc deficiency. Hum Mol Genet 16: 1391-1399. (Pubitemid 47055113)
    • (2007) Human Molecular Genetics , vol.16 , Issue.12 , pp. 1391-1399
    • Dufner-Beattie, J.1    Weaver, B.P.2    Geiser, J.3    Bilgen, M.4    Larson, M.5    Xu, W.6    Andrews, G.K.7
  • 17
    • 84864057714 scopus 로고    scopus 로고
    • A Mouse Model of Acrodermatitis Enteropathica: Loss of Intestine Zinc Transporter ZIP4 (Slc39a4) Disrupts the Stem Cell Niche and Intestine Integrity
    • Geiser J, Venken KJ, De Lisle RC, Andrews GK (2012) A Mouse Model of Acrodermatitis Enteropathica: Loss of Intestine Zinc Transporter ZIP4 (Slc39a4) Disrupts the Stem Cell Niche and Intestine Integrity. PLoS Genet 8: e1002766
    • (2012) PLoS Genet , vol.8
    • Geiser, J.1    Venken, K.J.2    De Lisle, R.C.3    Andrews, G.K.4
  • 18
    • 0036648254 scopus 로고    scopus 로고
    • Identification of SLC39A4, a gene involved in acrodermatitis enteropathica
    • Kury S, Dreno B, Bezieau S, Giraudet S, Kharfi M et al. (2002) Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Nat Genet 31: 239-240.
    • (2002) Nat Genet , vol.31 , pp. 239-240
    • Kury, S.1    Dreno, B.2    Bezieau, S.3    Giraudet, S.4    Kharfi, M.5
  • 19
    • 0036308552 scopus 로고    scopus 로고
    • A novel member of a zinc transporter family is defective in acrodermatitis enteropathica
    • DOI 10.1086/341125
    • Wang K, Zhou B, Kuo YM, Zemansky J, Gitschier J (2002) A novel member of a zinc transporter family is defective in acrodermatitis enteropathica. Am J Hum Genet 71: 66-73. (Pubitemid 34734708)
    • (2002) American Journal of Human Genetics , vol.71 , Issue.1 , pp. 66-73
    • Wang, K.1    Zhou, B.2    Kuo, Y.-M.3    Zemansky, J.4    Gitschier, J.5
  • 20
    • 84871225966 scopus 로고    scopus 로고
    • ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero
    • Galvez-Peralta M, He L, Jorge-Nebert LF, Wang B, Miller ML et al. (2012) ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero. PLoS One 7: e36055
    • (2012) PLoS One , vol.7
    • Galvez-Peralta, M.1    He, L.2    Jorge-Nebert, L.F.3    Wang, B.4    Miller, M.L.5
  • 22
    • 56649111126 scopus 로고    scopus 로고
    • The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways
    • Fukada T, Civic N, Furuichi T, Shimoda S, Mishima K et al. (2008) The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways. PLoS ONE 3: e3642
    • (2008) PLoS ONE , vol.3
    • Fukada, T.1    Civic, N.2    Furuichi, T.3    Shimoda, S.4    Mishima, K.5
  • 23
    • 79952977920 scopus 로고    scopus 로고
    • The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth
    • Hojyo S, Fukada T, Shimoda S, Ohashi W, Bin BH et al. (2011) The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth. PLoS ONE 6: e18059
    • (2011) PLoS ONE , vol.6
    • Hojyo, S.1    Fukada, T.2    Shimoda, S.3    Ohashi, W.4    Bin, B.H.5
  • 24
    • 84861601366 scopus 로고    scopus 로고
    • The zinc transporter Zip14 influences c-Met phosphorylation and hepatocyte proliferation during liver regeneration in mice
    • Aydemir TB, Sitren HS, Cousins RJ (2012) The zinc transporter Zip14 influences c-Met phosphorylation and hepatocyte proliferation during liver regeneration in mice. Gastroenterology 142: 1536-1546.
    • (2012) Gastroenterology , vol.142 , pp. 1536-1546
    • Aydemir, T.B.1    Sitren, H.S.2    Cousins, R.J.3
  • 25
    • 10344248917 scopus 로고    scopus 로고
    • The adaptive response to dietary zinc in mice involves the differential cellular localization and zinc regulation of the zinc transporters ZIP4 and ZIP5
    • DOI 10.1074/jbc.M409962200
    • Dufner-Beattie J, Kuo YM, Gitschier J, Andrews GK (2004) The adaptive response to dietary zinc in mice involves the differential cellular localization and zinc-regulation of the zinc transporters ZIP4 and ZIP5. J Biol Chem 279: 49082-49090. (Pubitemid 39625790)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 49082-49090
    • Dufner-Beattie, J.1    Kuo, Y.-M.2    Gitschier, J.3    Andrews, G.K.4
  • 26
    • 36248960703 scopus 로고    scopus 로고
    • Novel zinc-responsive post-transcriptional mechanisms reciprocally regulate expression of the mouse Slc39a4 and Slc39a5 zinc transporters (Zip4 and Zip5)
    • DOI 10.1515/BC.2007.149
    • Weaver BP, Dufner-Beattie J, Kambe T, Andrews GK (2007) Novel zinc-responsive post-transcriptional mechanisms reciprocally regulate expression of the mouse Slc39a4 and Slc39a5 zinc transporters (Zip4 and Zip5). Biol Chem 388: 1301-1312. (Pubitemid 350135568)
    • (2007) Biological Chemistry , vol.388 , Issue.12 , pp. 1301-1312
    • Weaver, B.P.1    Dufner-Beattie, J.2    Kambe, T.3    Andrews, G.K.4
  • 27
    • 84862768040 scopus 로고    scopus 로고
    • Regulation of zinc-responsive Slc39a5 (Zip5) translation is mediated by conserved elements in the 39-untranslated region
    • Weaver BP, Andrews GK (2012) Regulation of zinc-responsive Slc39a5 (Zip5) translation is mediated by conserved elements in the 39-untranslated region. Biometals 25: 319-335.
    • (2012) Biometals , vol.25 , pp. 319-335
    • Weaver, B.P.1    Andrews, G.K.2
  • 28
    • 84861059844 scopus 로고    scopus 로고
    • Zymophagy: Selective autophagy of secretory granules
    • Vaccaro MI (2012) Zymophagy: selective autophagy of secretory granules. Int J Cell Biol 2012: 396705
    • (2012) Int J Cell Biol , vol.2012 , pp. 396705
    • Vaccaro, M.I.1
  • 31
    • 52049101359 scopus 로고    scopus 로고
    • Robust acinar cell transgene expression of CreErT via BAC recombineering
    • Ji B, Song J, Tsou L, Bi Y, Gaiser S et al. (2008) Robust acinar cell transgene expression of CreErT via BAC recombineering. Genesis 46: 390-395.
    • (2008) Genesis , vol.46 , pp. 390-395
    • Ji, B.1    Song, J.2    Tsou, L.3    Bi, Y.4    Gaiser, S.5
  • 33
    • 70449426665 scopus 로고    scopus 로고
    • Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis
    • Mareninova OA, Hermann K, French SW, O'Konski MS, Pandol SJ et al. (2009) Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest 119: 3340-3355.
    • (2009) J Clin Invest , vol.119 , pp. 3340-3355
    • Mareninova, O.A.1    Hermann, K.2    French, S.W.3    O'Konski, M.S.4    Pandol, S.J.5
  • 34
    • 10944273358 scopus 로고    scopus 로고
    • The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells
    • DOI 10.1074/jbc.M408361200
    • Wang F, Kim BE, Petris MJ, Eide DJ (2004) The mammalian ZIP5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells. J Biol Chem 279: 51433-51441. (Pubitemid 40017891)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 51433-51441
    • Wang, F.1    Kim, B.-E.2    Petris, M.J.3    Eide, D.J.4
  • 36
    • 0034933893 scopus 로고    scopus 로고
    • Interrelationships of key variables of human zinc homeostasis: Relevance to dietary zinc requirements
    • DOI 10.1146/annurev.nutr.21.1.429
    • Hambidge M, Krebs NF (2001) Interrelationships of key variables of human zinc homeostasis: Relevance to dietary zinc requirements. Annu Rev Nutr 21: 429-452. (Pubitemid 32695279)
    • (2001) Annual Review of Nutrition , vol.21 , pp. 429-452
    • Hambidge, M.1    Krebs, N.F.2
  • 37
    • 0035693672 scopus 로고    scopus 로고
    • Zinc metabolism and homeostasis: The application of tracer techniques to human zinc physiology
    • Krebs NE, Hambidge KM (2001) Zinc metabolism and homeostasis: the application of tracer techniques to human zinc physiology. Biometals 14: 397-412.
    • (2001) Biometals , vol.14 , pp. 397-412
    • Krebs, N.E.1    Hambidge, K.M.2
  • 38
    • 84862306310 scopus 로고    scopus 로고
    • Zinc in specialized secretory tissues: Roles in the pancreas, prostate, and mammary gland
    • Kelleher SL, McCormick NH, Velasquez V, Lopez V (2011) Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland. Adv Nutr 2: 101-111.
    • (2011) Adv Nutr , vol.2 , pp. 101-111
    • Kelleher, S.L.1    McCormick, N.H.2    Velasquez, V.3    Lopez, V.4
  • 39
    • 0015538878 scopus 로고
    • Zinc metabolism in the rat. II. Secretion of zinc into intestine
    • Methfessel AH, Spencer H (1973) Zinc metabolism in the rat. II. Secretion of zinc into intestine. J Appl Physiol 34: 63-67.
    • (1973) J Appl Physiol , vol.34 , pp. 63-67
    • Methfessel, A.H.1    Spencer, H.2
  • 40
    • 0028086569 scopus 로고
    • The role of the pancreas in the regulation of zinc status
    • Van Wouwe JP, Uijlenbroek JJM (1994) The role of the pancreas in the regulation of zinc status. Biol Trace Elem Res 42: 143-150.
    • (1994) Biol Trace Elem Res , vol.42 , pp. 143-150
    • Van Wouwe, J.P.1    Uijlenbroek, J.J.M.2
  • 41
    • 0029991643 scopus 로고    scopus 로고
    • Mechanism of zinc homeostasis
    • Oberleas D (1996) Mechanism of zinc homeostasis. J Inorg Biochem 62: 231-241.
    • (1996) J Inorg Biochem , vol.62 , pp. 231-241
    • Oberleas, D.1
  • 43
    • 0037229776 scopus 로고    scopus 로고
    • Pancreatic metallothionein-I may play a role in zinc homeostasis during maternal dietary zinc deficiency in mice
    • Lee DK, Geiser J, Dufner-Beattie J, Andrews GK (2003) Pancreatic metallothionein-l may play a role in zinc homeostasis during maternal dietary zinc deficiency in mice. J Nutr 133: 45-50. (Pubitemid 36070575)
    • (2003) Journal of Nutrition , vol.133 , Issue.1 , pp. 45-50
    • Lee, D.K.1    Geiser, J.2    Dufner-Beattie, J.3    Andrews, G.K.4
  • 44
    • 0041355296 scopus 로고    scopus 로고
    • The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice
    • DOI 10.1074/jbc.M305000200
    • Dufner-Beattie J, Wang F, Kuo YM, Gitschier J, Eide D et al. (2003) The Acrodermatitis Enteropathica Gene ZIP4 Encodes a Tissue-specific, Zinc-regulated Zinc Transporter in Mice. J Biol Chem 278: 33474-33481. (Pubitemid 37055802)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.35 , pp. 33474-33481
    • Dufner-Beattie, J.1    Wang, F.2    Kuo, Y.-M.3    Gitschier, J.4    Eide, D.5    Andrews, G.K.6
  • 45
    • 55949131237 scopus 로고    scopus 로고
    • Development of a compartmental model of zinc kinetics in mice
    • Wastney ME, House WA (2008) Development of a compartmental model of zinc kinetics in mice. J Nutr 138: 2148-2155.
    • (2008) J Nutr , vol.138 , pp. 2148-2155
    • Wastney, M.E.1    House, W.A.2
  • 46
    • 84877978900 scopus 로고    scopus 로고
    • ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: Implications for tissue iron uptake in iron-related disorders
    • Nam H, Wang CY, Zhang L, Zhang W, Hojyo S et al. (2013) ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders. Haematologica 98: 1049-1057.
    • (2013) Haematologica , vol.98 , pp. 1049-1057
    • Nam, H.1    Wang, C.Y.2    Zhang, L.3    Zhang, W.4    Hojyo, S.5
  • 47
    • 33745040492 scopus 로고    scopus 로고
    • Mouse ZIP1 and ZIP3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy
    • DOI 10.1002/dvg.20211
    • Dufner-Beattie J, Huang ZL, Geiser J, Xu W, Andrews GK (2006) Mouse ZIP1 and ZIP3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy. Genesis 44: 239-251. (Pubitemid 43877468)
    • (2006) Genesis , vol.44 , Issue.5 , pp. 239-251
    • Dufner-Beattie, J.1    Huang, Z.L.2    Geiser, J.3    Xu, W.4    Andrews, G.K.5
  • 48
    • 0029858934 scopus 로고    scopus 로고
    • Metallothionein is a component of exocrine pancreas secretion: Implications for zinc homeostasis
    • De Lisle RC, Sarras MP, Jr., Hidalgo J, Andrews GK (1996) Metallothionein is a component of exocrine pancreas secretion: Implications for zinc homeostasis. Am J Physiol Cell Physiol 271: C1103-C1110
    • (1996) Am J Physiol Cell Physiol , vol.271
    • De Lisle, R.C.1    Sarras Jr., M.P.2    Hidalgo, J.3    Andrews, G.K.4
  • 49
    • 0031687147 scopus 로고    scopus 로고
    • Metallothionein protects against cerulein-induced acute pancreatitis: Analysis using transgenic mice
    • Fu K, Tomita T, Sarras MP, Jr., De Lisle RC, Andrews GK (1998) Metallothionein protects against cerulein-induced acute pancreatitis: Analysis using transgenic mice. Pancreas 17: 238-246. (Pubitemid 28455708)
    • (1998) Pancreas , vol.17 , Issue.3 , pp. 238-246
    • Fu, K.1    Tomita, T.2    Sarras Jr., M.P.3    De Lisle, R.C.4    Andrews, G.K.5
  • 50
    • 79958777099 scopus 로고    scopus 로고
    • Assessment of oxidative status in chronic pancreatitis and its relation with zinc status
    • Girish BN, Rajesh G, Vaidyanathan K, Balakrishnan V (2011) Assessment of oxidative status in chronic pancreatitis and its relation with zinc status. Indian J Gastroenterol 30: 84-88.
    • (2011) Indian J Gastroenterol , vol.30 , pp. 84-88
    • Girish, B.N.1    Rajesh, G.2    Vaidyanathan, K.3    Balakrishnan, V.4
  • 51
    • 84924267116 scopus 로고    scopus 로고
    • Effects of micronutrient status on oxidative stress and exocrine pancreatic function in patients with chronic pancreatitis
    • Girish BN, Vaidyanathan K, Rajesh G, Balakrishnan V (2012) Effects of micronutrient status on oxidative stress and exocrine pancreatic function in patients with chronic pancreatitis. Indian J Biochem Biophys 49: 386-391.
    • (2012) Indian J Biochem Biophys , vol.49 , pp. 386-391
    • Girish, B.N.1    Vaidyanathan, K.2    Rajesh, G.3    Balakrishnan, V.4
  • 55
    • 0035487293 scopus 로고    scopus 로고
    • Recombineering: A powerful new tool for mouse functional genomics
    • DOI 10.1038/35093556
    • Copeland NG, Jenkins NA, Court DL (2001) Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet 2: 769-779. (Pubitemid 33685574)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.10 , pp. 769-779
    • Copeland, N.G.1    Jenkins, N.A.2    Court, D.L.3
  • 57
    • 0036739377 scopus 로고    scopus 로고
    • Conditionally amplifiable BACs: Switching from single-copy to high-copy vectors and genomic clones
    • Wild J, Hradecna Z, Szybalski W (2002) Conditionally amplifiable BACs: switching from single-copy to high-copy vectors and genomic clones. Genome Res 12: 1434-1444.
    • (2002) Genome Res , vol.12 , pp. 1434-1444
    • Wild, J.1    Hradecna, Z.2    Szybalski, W.3
  • 58
    • 33845698104 scopus 로고    scopus 로고
    • P[acman]: A BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster
    • DOI 10.1126/science.1134426
    • Venken KJ, He Y, Hoskins RA, Bellen HJ (2006) P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster. Science 314: 1747-1751. (Pubitemid 44969080)
    • (2006) Science , vol.314 , Issue.5806 , pp. 1747-1751
    • Venken, K.J.T.1    He, Y.2    Hoskins, R.A.3    Bellen, H.J.4
  • 59
    • 0034842640 scopus 로고    scopus 로고
    • Site- and time-specific gene targeting in the mouse
    • DOI 10.1006/meth.2001.1159
    • Metzger D, Chambon P (2001) Site- and time-specific gene targeting in the mouse. Methods 24: 71-80. (Pubitemid 32846445)
    • (2001) Methods , vol.24 , Issue.1 , pp. 71-80
    • Metzger, D.1    Chambon, P.2
  • 60
    • 34247198420 scopus 로고    scopus 로고
    • Purdue ionomics information management system. An integrated functional genomics platform
    • DOI 10.1104/pp.106.092528
    • Baxter I, Ouzzani M, Orcun S, Kennedy B, Jandhyala SS et al. (2007) Purdue ionomics information management system. An integrated functional genomics platform. Plant Physiol 143: 600-611. (Pubitemid 46940952)
    • (2007) Plant Physiology , vol.143 , Issue.2 , pp. 600-611
    • Baxter, I.1    Ouzzani, M.2    Orcun, S.3    Kennedy, B.4    Jandhyala, S.S.5    Salt, D.E.6
  • 61
    • 34347328067 scopus 로고    scopus 로고
    • Targeting of the mouse Slc39a2 (Zip2) gene reveals highly cell-specific patterns of expression, and unique functions in zinc, iron, and calcium homeostasis
    • DOI 10.1002/dvg.20297
    • Peters JL, Dufner-Beattie J, Xu W, Geiser J, Lahner B et al. (2007) Targeting of the mouse Slc39a2 (Zip2) gene reveals highly cell-specific patterns of expression, and unique functions in zinc, iron and calcium homeostasis. Genesis 45: 339-352. (Pubitemid 47015320)
    • (2007) Genesis , vol.45 , Issue.6 , pp. 339-352
    • Peters, J.L.1    Dufner-Beattie, J.2    Xu, W.3    Geiser, J.4    Lahner, B.5    Salt, D.E.6    Andrews, G.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.