메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages

Wnt modulates MCL1 to control cell survival in triple negative breast cancer

Author keywords

MCL1; Triple negative breast cancer (TNBC); WNT catenin pathway; WNT5B

Indexed keywords

CASPASE; LIGAND; MITOCHONDRIAL DNA; MYC PROTEIN; PROTEIN MCL 1; SHORT HAIRPIN RNA; WNT5B PROTEIN;

EID: 84896737860     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-124     Document Type: Article
Times cited : (51)

References (43)
  • 2
    • 38449115081 scopus 로고    scopus 로고
    • Overview of resistance to systemic therapy in patients with breast cancer
    • 10.1007/978-0-387-74039-3_1, 17993229
    • Gonzalez-Angulo AM, Morales-Vasquez F, Hortobagyi GN. Overview of resistance to systemic therapy in patients with breast cancer. Adv Exp Med Biol 2007, 608:1-22. 10.1007/978-0-387-74039-3_1, 17993229.
    • (2007) Adv Exp Med Biol , vol.608 , pp. 1-22
    • Gonzalez-Angulo, A.M.1    Morales-Vasquez, F.2    Hortobagyi, G.N.3
  • 3
    • 84867129194 scopus 로고    scopus 로고
    • Adjuvant treatments for triple-negative breast cancers
    • Joensuu H, Gligorov J. Adjuvant treatments for triple-negative breast cancers. Ann Oncol 2012, 23(Suppl 6):vi40-vi45.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 6
    • Joensuu, H.1    Gligorov, J.2
  • 4
    • 84655162706 scopus 로고    scopus 로고
    • Treatment of HER2-positive breast cancer: current status and future perspectives
    • 10.1038/nrclinonc.2011.177, 22124364
    • Arteaga CL, Sliwkowski MX, Osborne CK, Perez EA, Puglisi F, Gianni L. Treatment of HER2-positive breast cancer: current status and future perspectives. Nat Rev Clin Oncol 2011, 9(1):16-32. 10.1038/nrclinonc.2011.177, 22124364.
    • (2011) Nat Rev Clin Oncol , vol.9 , Issue.1 , pp. 16-32
    • Arteaga, C.L.1    Sliwkowski, M.X.2    Osborne, C.K.3    Perez, E.A.4    Puglisi, F.5    Gianni, L.6
  • 5
    • 76449115473 scopus 로고    scopus 로고
    • Chemotherapy: dose-dense treatment for triple-negative breast cancer
    • 10.1038/nrclinonc.2009.231, 20118978
    • Amir E, Ocana A, Freedman O, Clemons M, Seruga B. Chemotherapy: dose-dense treatment for triple-negative breast cancer. Nat Rev Clin Oncol 2010, 7(2):79-80. 10.1038/nrclinonc.2009.231, 20118978.
    • (2010) Nat Rev Clin Oncol , vol.7 , Issue.2 , pp. 79-80
    • Amir, E.1    Ocana, A.2    Freedman, O.3    Clemons, M.4    Seruga, B.5
  • 6
    • 70849122251 scopus 로고    scopus 로고
    • Triple-negative breast cancer-current status and future directions
    • 10.1093/annonc/mdp492, 19901010
    • Gluz O, Liedtke C, Gottschalk N, Pusztai L, Nitz U, Harbeck N. Triple-negative breast cancer-current status and future directions. Ann Oncol 2009, 20(12):1913-1927. 10.1093/annonc/mdp492, 19901010.
    • (2009) Ann Oncol , vol.20 , Issue.12 , pp. 1913-1927
    • Gluz, O.1    Liedtke, C.2    Gottschalk, N.3    Pusztai, L.4    Nitz, U.5    Harbeck, N.6
  • 8
    • 67650496215 scopus 로고    scopus 로고
    • A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer
    • 10.1158/0008-5472.CAN-08-4135, 2782448, 19549913
    • DiMeo TA, Anderson K, Phadke P, Fan C, Perou CM, Naber S, Kuperwasser C. A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res 2009, 69(13):5364-5373. 10.1158/0008-5472.CAN-08-4135, 2782448, 19549913.
    • (2009) Cancer Res , vol.69 , Issue.13 , pp. 5364-5373
    • DiMeo, T.A.1    Anderson, K.2    Phadke, P.3    Fan, C.4    Perou, C.M.5    Naber, S.6    Kuperwasser, C.7
  • 9
    • 36249025636 scopus 로고    scopus 로고
    • Wnt signaling, stem cells, and the cellular origin of breast cancer
    • 10.1007/s12015-007-0025-3, 17873348
    • Lindvall C, Bu W, Williams BO, Li Y. Wnt signaling, stem cells, and the cellular origin of breast cancer. Stem Cell Rev 2007, 3(2):157-168. 10.1007/s12015-007-0025-3, 17873348.
    • (2007) Stem Cell Rev , vol.3 , Issue.2 , pp. 157-168
    • Lindvall, C.1    Bu, W.2    Williams, B.O.3    Li, Y.4
  • 10
    • 84862526929 scopus 로고    scopus 로고
    • The clonal and mutational evolution spectrum of primary triple-negative breast cancers
    • 3863681, 22495314
    • Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012, 486(7403):395-399. 3863681, 22495314.
    • (2012) Nature , vol.486 , Issue.7403 , pp. 395-399
    • Shah, S.P.1    Roth, A.2    Goya, R.3    Oloumi, A.4    Ha, G.5    Zhao, Y.6    Turashvili, G.7    Ding, J.8    Tse, K.9    Haffari, G.10
  • 11
    • 80055040407 scopus 로고    scopus 로고
    • FZD7 has a critical role in cell proliferation in triple negative breast cancer
    • 10.1038/onc.2011.145, 21532620
    • Yang L, Wu X, Wang Y, Zhang K, Wu J, Yuan YC, Deng X, Chen L, Kim CC, Lau S, et al. FZD7 has a critical role in cell proliferation in triple negative breast cancer. Oncogene 2011, 30(43):4437-4446. 10.1038/onc.2011.145, 21532620.
    • (2011) Oncogene , vol.30 , Issue.43 , pp. 4437-4446
    • Yang, L.1    Wu, X.2    Wang, Y.3    Zhang, K.4    Wu, J.5    Yuan, Y.C.6    Deng, X.7    Chen, L.8    Kim, C.C.9    Lau, S.10
  • 12
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • 10.1016/j.cell.2006.10.018, 17081971
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127(3):469-480. 10.1016/j.cell.2006.10.018, 17081971.
    • (2006) Cell , vol.127 , Issue.3 , pp. 469-480
    • Clevers, H.1
  • 13
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: components, mechanisms, and diseases
    • 10.1016/j.devcel.2009.06.016, 2861485, 19619488
    • MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009, 17(1):9-26. 10.1016/j.devcel.2009.06.016, 2861485, 19619488.
    • (2009) Dev Cell , vol.17 , Issue.1 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 14
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • 10.1038/nature03319, 15829953
    • Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005, 434(7035):843-850. 10.1038/nature03319, 15829953.
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 15
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
    • 10.1126/science.275.5307.1784, 9065401
    • Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 1997, 275(5307):1784-1787. 10.1126/science.275.5307.1784, 9065401.
    • (1997) Science , vol.275 , Issue.5307 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3    van Wichen, D.4    de Weger, R.5    Kinzler, K.W.6    Vogelstein, B.7    Clevers, H.8
  • 16
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • 10.1126/science.275.5307.1787, 9065402
    • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275(5307):1787-1790. 10.1126/science.275.5307.1787, 9065402.
    • (1997) Science , vol.275 , Issue.5307 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6    Kinzler, K.W.7
  • 17
    • 61449249121 scopus 로고    scopus 로고
    • Selective activation mechanisms of Wnt signaling pathways
    • 10.1016/j.tcb.2009.01.003, 19208479
    • Kikuchi A, Yamamoto H, Sato A. Selective activation mechanisms of Wnt signaling pathways. Trends Cell Biol 2009, 19(3):119-129. 10.1016/j.tcb.2009.01.003, 19208479.
    • (2009) Trends Cell Biol , vol.19 , Issue.3 , pp. 119-129
    • Kikuchi, A.1    Yamamoto, H.2    Sato, A.3
  • 18
    • 70349932747 scopus 로고    scopus 로고
    • Towards an integrated view of Wnt signaling in development
    • 10.1242/dev.033910, 19736321
    • van Amerongen R, Nusse R. Towards an integrated view of Wnt signaling in development. Development 2009, 136(19):3205-3214. 10.1242/dev.033910, 19736321.
    • (2009) Development , vol.136 , Issue.19 , pp. 3205-3214
    • van Amerongen, R.1    Nusse, R.2
  • 20
    • 68749112707 scopus 로고    scopus 로고
    • Importing mitochondrial proteins: machineries and mechanisms
    • 10.1016/j.cell.2009.08.005, 19703392
    • Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N. Importing mitochondrial proteins: machineries and mechanisms. Cell 2009, 138(4):628-644. 10.1016/j.cell.2009.08.005, 19703392.
    • (2009) Cell , vol.138 , Issue.4 , pp. 628-644
    • Chacinska, A.1    Koehler, C.M.2    Milenkovic, D.3    Lithgow, T.4    Pfanner, N.5
  • 21
    • 84870206960 scopus 로고    scopus 로고
    • Mitochondria: master regulators of danger signalling
    • 10.1038/nrm3479, 23175281
    • Galluzzi L, Kepp O, Kroemer G. Mitochondria: master regulators of danger signalling. Nat Rev Mol Cell Biol 2012, 13(12):780-788. 10.1038/nrm3479, 23175281.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.12 , pp. 780-788
    • Galluzzi, L.1    Kepp, O.2    Kroemer, G.3
  • 22
    • 84866665390 scopus 로고    scopus 로고
    • Mitochondria and cancer
    • 10.1038/nrc3365, 23001348
    • Wallace DC. Mitochondria and cancer. Nat Rev Cancer 2012, 12(10):685-698. 10.1038/nrc3365, 23001348.
    • (2012) Nat Rev Cancer , vol.12 , Issue.10 , pp. 685-698
    • Wallace, D.C.1
  • 23
    • 84907095419 scopus 로고    scopus 로고
    • R: A Language and Environment for Statistical Computing
    • R Development Core Team
    • R Development Core Team R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing 2013, R Development Core Team.
    • (2013) R Foundation for Statistical Computing
  • 25
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • 10.1038/nature11412, 3465532, 23000897, The Cancer Genome Atlas Network
    • The Cancer Genome Atlas Network Comprehensive molecular portraits of human breast tumours. Nature 2012, 490(7418):61-70. 10.1038/nature11412, 3465532, 23000897, The Cancer Genome Atlas Network.
    • (2012) Nature , vol.490 , Issue.7418 , pp. 61-70
  • 26
    • 34250652449 scopus 로고    scopus 로고
    • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG Multicenter Independent Validation Series
    • 10.1158/1078-0432.CCR-06-2765, 17545524
    • Desmedt C, Piette F, Loi S, Wang Y, Lallemand F, Haibe-Kains B, Viale G, Delorenzi M, Zhang Y, d'Assignies MS, et al. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG Multicenter Independent Validation Series. Clin Cancer Res 2007, 13(11):3207-3214. 10.1158/1078-0432.CCR-06-2765, 17545524.
    • (2007) Clin Cancer Res , vol.13 , Issue.11 , pp. 3207-3214
    • Desmedt, C.1    Piette, F.2    Loi, S.3    Wang, Y.4    Lallemand, F.5    Haibe-Kains, B.6    Viale, G.7    Delorenzi, M.8    Zhang, Y.9    d'Assignies, M.S.10
  • 27
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
    • 10.1016/S0140-6736(05)17947-1, 15721472
    • Wang Y, Klijn JGM, Zhang Y, Sieuwerts AM, Look MP, Yang F, Talantov D, Timmermans M, Meijer-van Gelder ME, Yu J, et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 2005, 365(9460):671-679. 10.1016/S0140-6736(05)17947-1, 15721472.
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.M.2    Zhang, Y.3    Sieuwerts, A.M.4    Look, M.P.5    Yang, F.6    Talantov, D.7    Timmermans, M.8    Meijer-van Gelder, M.E.9    Yu, J.10
  • 28
    • 34548021647 scopus 로고    scopus 로고
    • Conventional specimen preparation techniques for transmission electron microscopy of cultured cells
    • Bozzola JJ. Conventional specimen preparation techniques for transmission electron microscopy of cultured cells. Meth Mol Biol (Clifton, NJ) 2007, 369:1-18.
    • (2007) Meth Mol Biol (Clifton, NJ) , vol.369 , pp. 1-18
    • Bozzola, J.J.1
  • 30
    • 67749089562 scopus 로고    scopus 로고
    • A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase
    • 10.1073/pnas.0904875106, 2710990, 19617534
    • Mitra K, Wunder C, Roysam B, Lin G, Lippincott-Schwartz J. A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc Natl Acad Sci U S A 2009, 106(29):11960-11965. 10.1073/pnas.0904875106, 2710990, 19617534.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.29 , pp. 11960-11965
    • Mitra, K.1    Wunder, C.2    Roysam, B.3    Lin, G.4    Lippincott-Schwartz, J.5
  • 32
    • 84860335512 scopus 로고    scopus 로고
    • MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors
    • 10.4161/cc.20008, 22456335
    • Labisso WL, Wirth M, Stojanovic N, Stauber RH, Schnieke A, Schmid RM, Kramer OH, Saur D, Schneider G. MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors. Cell Cycle 2012, 11(8):1593-1602. 10.4161/cc.20008, 22456335.
    • (2012) Cell Cycle , vol.11 , Issue.8 , pp. 1593-1602
    • Labisso, W.L.1    Wirth, M.2    Stojanovic, N.3    Stauber, R.H.4    Schnieke, A.5    Schmid, R.M.6    Kramer, O.H.7    Saur, D.8    Schneider, G.9
  • 34
    • 10844230334 scopus 로고    scopus 로고
    • Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells
    • 10.1158/0008-5472.CAN-04-2370, 15604245
    • Verras M, Brown J, Li X, Nusse R, Sun Z. Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells. Cancer Res 2004, 64(24):8860-8866. 10.1158/0008-5472.CAN-04-2370, 15604245.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 8860-8866
    • Verras, M.1    Brown, J.2    Li, X.3    Nusse, R.4    Sun, Z.5
  • 35
    • 59049101982 scopus 로고    scopus 로고
    • Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
    • 10.1073/pnas.0811902106, 2626610, 19144919
    • Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT. Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci U S A 2009, 106(4):1193-1198. 10.1073/pnas.0811902106, 2626610, 19144919.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.4 , pp. 1193-1198
    • Chien, A.J.1    Moore, E.C.2    Lonsdorf, A.S.3    Kulikauskas, R.M.4    Rothberg, B.G.5    Berger, A.J.6    Major, M.B.7    Hwang, S.T.8    Rimm, D.L.9    Moon, R.T.10
  • 36
    • 77954851049 scopus 로고    scopus 로고
    • Wnt signaling regulates mitochondrial physiology and insulin sensitivity
    • 10.1101/gad.1924910, 2904941, 20634317
    • Yoon JC, Ng A, Kim BH, Bianco A, Xavier RJ, Elledge SJ. Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev 2010, 24(14):1507-1518. 10.1101/gad.1924910, 2904941, 20634317.
    • (2010) Genes Dev , vol.24 , Issue.14 , pp. 1507-1518
    • Yoon, J.C.1    Ng, A.2    Kim, B.H.3    Bianco, A.4    Xavier, R.J.5    Elledge, S.J.6
  • 38
    • 84876475662 scopus 로고    scopus 로고
    • Programming cancer cells for high expression levels of Mcl1
    • 10.1038/embor.2013.20, 23478333
    • Ertel F, Nguyen M, Roulston A, Shore GC. Programming cancer cells for high expression levels of Mcl1. EMBO Rep 2013, 14(4):328-336. 10.1038/embor.2013.20, 23478333.
    • (2013) EMBO Rep , vol.14 , Issue.4 , pp. 328-336
    • Ertel, F.1    Nguyen, M.2    Roulston, A.3    Shore, G.C.4
  • 39
    • 84983718691 scopus 로고    scopus 로고
    • Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
    • 10.1038/cddis.2013.18, 3734819, 23392173
    • Tai WT, Shiau CW, Chen HL, Liu CY, Lin CS, Cheng AL, Chen PJ, Chen KF. Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells. Cell Death Dis 2013, 4:e485. 10.1038/cddis.2013.18, 3734819, 23392173.
    • (2013) Cell Death Dis , vol.4
    • Tai, W.T.1    Shiau, C.W.2    Chen, H.L.3    Liu, C.Y.4    Lin, C.S.5    Cheng, A.L.6    Chen, P.J.7    Chen, K.F.8
  • 40
    • 84859825629 scopus 로고    scopus 로고
    • Chemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependency
    • 10.1016/j.ccr.2012.02.028, 3685408, 22516262
    • Wei G, Margolin AA, Haery L, Brown E, Cucolo L, Julian B, Shehata S, Kung AL, Beroukhim R, Golub TR. Chemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependency. Cancer Cell 2012, 21(4):547-562. 10.1016/j.ccr.2012.02.028, 3685408, 22516262.
    • (2012) Cancer Cell , vol.21 , Issue.4 , pp. 547-562
    • Wei, G.1    Margolin, A.A.2    Haery, L.3    Brown, E.4    Cucolo, L.5    Julian, B.6    Shehata, S.7    Kung, A.L.8    Beroukhim, R.9    Golub, T.R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.