Targeting of herpes simplex virus 1 thymidine kinase gene sequences into the OCT4 locus of human induced pluripotent stem cells

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Ou, Wu ^a   Li, Pingjuan ^a   Reiser, Jakob ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; OCTAMER TRANSCRIPTION FACTOR 4; PUROMYCIN; ZINC FINGER NUCLEASE; DEOXYRIBONUCLEASE; POU5F1 PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; RHO KINASE; THYMIDINE KINASE; ZINC FINGER PROTEIN;

ARTICLE; CELL CLONE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEPLETION; DNA FLANKING REGION; DRUG SENSITIVITY; GENE CASSETTE; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE TARGETING; GENETIC STABILITY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS 1 THYMIDINE KINASE GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; PATIENT SAFETY; PLASMID; PLURIPOTENT STEM CELL; PROMOTER REGION; STEM CELL TRANSPLANTATION; SUICIDE GENE; TRANSGENE; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; ENZYMOLOGY; GENETICS; HERPES SIMPLEX VIRUS 1; METABOLISM; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CELL LINE; DEOXYRIBONUCLEASES; DRUG RESISTANCE; GANCICLOVIR; GENE TARGETING; GENETIC LOCI; HERPESVIRUS 1, HUMAN; HUMANS; INDUCED PLURIPOTENT STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PROTEIN KINASE INHIBITORS; PUROMYCIN; RHO-ASSOCIATED KINASES; THYMIDINE KINASE; ZINC FINGERS;

EID: 84896733430     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081131     Document Type: Article

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