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Volumn 24, Issue 2 B, 2004, Pages 827-831

Resistance Developing after Long-term Ganciclovir Prodrug Treatment in a Preclinical Model of NSCLC

Author keywords

Gene therapy; Herpes simplex virus thymidine kinase; Lung cancer; Retroviral vector

Indexed keywords

GANCICLOVIR; PRODRUG; THYMIDINE KINASE;

EID: 2442434755     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (23)
  • 1
    • 0030046154 scopus 로고    scopus 로고
    • Treatment of pleural mesothelioma in an immunocompetent rat model utilizing adenoviral transfer of the herpes simplex virus thymidine kinase gene
    • Elshami AA, Kucharczuk JC, Zhang HB et al: Treatment of pleural mesothelioma in an immunocompetent rat model utilizing adenoviral transfer of the herpes simplex virus thymidine kinase gene. Hum Gene Ther 7: 141-148, 1996.
    • (1996) Hum Gene Ther , vol.7 , pp. 141-148
    • Elshami, A.A.1    Kucharczuk, J.C.2    Zhang, H.B.3
  • 2
    • 0033193069 scopus 로고    scopus 로고
    • Retrovirus-mediated herpes simplex virus thymidine kinase gene therapy approach for hepatocellular carcinoma
    • Gao Ding C, An W and Dai J: Retrovirus-mediated herpes simplex virus thymidine kinase gene therapy approach for hepatocellular carcinoma. Cell Res 9: 225-235, 1999.
    • (1999) Cell Res , vol.9 , pp. 225-235
    • Gao Ding, C.1    An, W.2    Dai, J.3
  • 3
    • 0025444099 scopus 로고
    • Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene
    • Moolten FL, Wells JM, Heyman RA and Evans RM: Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene. Hum Gene Ther 1: 125-134, 1990.
    • (1990) Hum Gene Ther , vol.1 , pp. 125-134
    • Moolten, F.L.1    Wells, J.M.2    Heyman, R.A.3    Evans, R.M.4
  • 4
    • 0034101114 scopus 로고    scopus 로고
    • Mitochondrial amplification of death signals determines thymidine kinase/ganciclovir-triggered activation of apoptosis
    • Beltinger C, Fulda S, Kammertoens T, Uckert W and Debatin KM: Mitochondrial amplification of death signals determines thymidine kinase/ganciclovir-triggered activation of apoptosis. Cancer Res 60: 3212-3217, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3212-3217
    • Beltinger, C.1    Fulda, S.2    Kammertoens, T.3    Uckert, W.4    Debatin, K.M.5
  • 5
    • 0030668915 scopus 로고    scopus 로고
    • A "distant" bystander effect of suicide gene therapy: Regression of nontransduced tumors together with a distant transduced tumor
    • Kianmanesh AR, Perrin H, Panis Y et al: A "distant" bystander effect of suicide gene therapy: regression of nontransduced tumors together with a distant transduced tumor. Hum Gene Ther 8: 1807-1814, 1997.
    • (1997) Hum Gene Ther , vol.8 , pp. 1807-1814
    • Kianmanesh, A.R.1    Perrin, H.2    Panis, Y.3
  • 6
    • 0032552436 scopus 로고    scopus 로고
    • Ganciclovir chemoablation of herpes thymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses
    • Mullen CA, Anderson L, Woods K, Nishino M and Petropoulos D: Ganciclovir chemoablation of herpes thymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses. Hum Gene Ther 9: 2019-2030, 1998.
    • (1998) Hum Gene Ther , vol.9 , pp. 2019-2030
    • Mullen, C.A.1    Anderson, L.2    Woods, K.3    Nishino, M.4    Petropoulos, D.5
  • 7
    • 0030757097 scopus 로고    scopus 로고
    • The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions
    • Vrionis FD, Wu JK, Qi P et al: The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions. Gene Ther 4: 577-585, 1997.
    • (1997) Gene Ther , vol.4 , pp. 577-585
    • Vrionis, F.D.1    Wu, J.K.2    Qi, P.3
  • 9
    • 0033588816 scopus 로고    scopus 로고
    • A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
    • GLI328 European-Canadian Study Group
    • Shand N, Weber F, Mariani L et al: A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum Gene Ther 10: 2325-2335, 1999.
    • (1999) Hum Gene Ther , vol.10 , pp. 2325-2335
    • Shand, N.1    Weber, F.2    Mariani, L.3
  • 10
    • 0031949646 scopus 로고    scopus 로고
    • Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene
    • Yang L, Hwang R, Chiang Y et al: Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene. Clin Cancer Res 4: 731-741, 1998.
    • (1998) Clin Cancer Res , vol.4 , pp. 731-741
    • Yang, L.1    Hwang, R.2    Chiang, Y.3
  • 11
    • 0030956975 scopus 로고    scopus 로고
    • Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo
    • Zhang L, Wikenheiser KA and Whitsett JA: Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo. Hum Gene Ther 8: 563-574, 1997.
    • (1997) Hum Gene Ther , vol.8 , pp. 563-574
    • Zhang, L.1    Wikenheiser, K.A.2    Whitsett, J.A.3
  • 12
    • 0036186162 scopus 로고    scopus 로고
    • Ganciclovir prodrug therapy is effective in a murine xenotransplant model of human lung cancer
    • Kurdow R, Boehle AS, Haye S et al: Ganciclovir prodrug therapy is effective in a murine xenotransplant model of human lung cancer. Ann Thorac Surg 73: 905-910, 2002.
    • (2002) Ann Thorac Surg , vol.73 , pp. 905-910
    • Kurdow, R.1    Boehle, A.S.2    Haye, S.3
  • 13
    • 0034676268 scopus 로고    scopus 로고
    • Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis
    • Hinz S, Trauzold A, Boenicke L et al: Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis. Oncogene 19: 5477-5486, 2000.
    • (2000) Oncogene , vol.19 , pp. 5477-5486
    • Hinz, S.1    Trauzold, A.2    Boenicke, L.3
  • 14
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • Tomayko MM and Reynolds CP: Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother Pharmacol 24: 148-154, 1989.
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2
  • 15
    • 0037812853 scopus 로고    scopus 로고
    • Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir
    • Smitt PS, Driesse M, Wolbers J, Kros M and Avezaat C: Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir. Mol Ther 7: 851-858, 2003.
    • (2003) Mol Ther , vol.7 , pp. 851-858
    • Smitt, P.S.1    Driesse, M.2    Wolbers, J.3    Kros, M.4    Avezaat, C.5
  • 16
    • 0026775292 scopus 로고
    • Herpes simplex-1 virus thymidine kinase gene is unable to completely eliminate live, nonimmunogenic tumor cell vaccines
    • Golumbek PT, Hamzeh FM, Jaffee EM et al: Herpes simplex-1 virus thymidine kinase gene is unable to completely eliminate live, nonimmunogenic tumor cell vaccines. J Immunother 12: 224-230, 1992.
    • (1992) J Immunother , vol.12 , pp. 224-230
    • Golumbek, P.T.1    Hamzeh, F.M.2    Jaffee, E.M.3
  • 17
    • 0028212859 scopus 로고
    • Methylation of single sites within the herpes simplex virus tk coding region and the simian virus 40 T-antigen intron causes gene inactivation
    • Graessmann A, Sandberg G, Guhl E and Graessmann M: Methylation of single sites within the herpes simplex virus tk coding region and the simian virus 40 T-antigen intron causes gene inactivation. Mol Cell Biol 14: 2004-2010, 1994.
    • (1994) Mol Cell Biol , vol.14 , pp. 2004-2010
    • Graessmann, A.1    Sandberg, G.2    Guhl, E.3    Graessmann, M.4
  • 18
    • 0028940302 scopus 로고
    • Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance
    • Chou S, Erice A, Jordan MC et al: Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance. J Infect Dis 171: 576-583, 1995.
    • (1995) J Infect Dis , vol.171 , pp. 576-583
    • Chou, S.1    Erice, A.2    Jordan, M.C.3
  • 19
    • 0028859327 scopus 로고
    • Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma
    • Wolf DG, Smith IL, Lee DJ et al: Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma. J Clin Invest 95: 257-263, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 257-263
    • Wolf, D.G.1    Smith, I.L.2    Lee, D.J.3
  • 20
    • 0035106088 scopus 로고    scopus 로고
    • Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
    • Agard C, Ligeza C, Dupas B et al: Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Ther 8: 128-136, 2001.
    • (2001) Cancer Gene Ther , vol.8 , pp. 128-136
    • Agard, C.1    Ligeza, C.2    Dupas, B.3
  • 21
    • 0038339601 scopus 로고    scopus 로고
    • Combination of adenovirus-mediated thymidine kinase gene therapy with cytotoxic chemotherapy in bladder cancer in vitro
    • Freund CT, Tong XW, Rowley D et al: Combination of adenovirus-mediated thymidine kinase gene therapy with cytotoxic chemotherapy in bladder cancer in vitro. Urol Oncol 21: 197-205, 2003.
    • (2003) Urol Oncol , vol.21 , pp. 197-205
    • Freund, C.T.1    Tong, X.W.2    Rowley, D.3
  • 22
    • 0031730806 scopus 로고    scopus 로고
    • Adenovirus mediated thymidine kinase gene therapy may enhance sensitivity of ovarian cancer cells to chemotherapeutic agents
    • Tong X, Shine DH, Agoulnik I et al: Adenovirus mediated thymidine kinase gene therapy may enhance sensitivity of ovarian cancer cells to chemotherapeutic agents. Anticancer Res 18: 3421-3426, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 3421-3426
    • Tong, X.1    Shine, D.H.2    Agoulnik, I.3
  • 23
    • 10744232977 scopus 로고    scopus 로고
    • Gene therapy with GM-CSF, interleukin-4 and herpes simplex virus thymidine kinase shows strong antitumor effect on lung cancer
    • Park KH, Kim G, Jang SH et al: Gene therapy with GM-CSF, interleukin-4 and herpes simplex virus thymidine kinase shows strong antitumor effect on lung cancer. Anticancer Res 23: 1559-1564, 2003.
    • (2003) Anticancer Res , vol.23 , pp. 1559-1564
    • Park, K.H.1    Kim, G.2    Jang, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.