-
1
-
-
17144458786
-
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
-
Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S and Pelicci PG: Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia. Nature 391: 815-818, 1998.
-
(1998)
Nature
, vol.391
, pp. 815-818
-
-
Grignani, F.1
De Matteis, S.2
Nervi, C.3
Tomassoni, L.4
Gelmetti, V.5
Cioce, M.6
Fanelli, M.7
Ruthardt, M.8
Ferrara, F.F.9
Zamir, I.10
Seiser, C.11
Grignani, F.12
Lazar, M.A.13
Minucci, S.14
Pelicci, P.G.15
-
2
-
-
0032546017
-
Role of the histone deacetylase complex in acute promyelocytic leukaemia
-
Lin RJ, Nagy L, Inoue S, Shao W, Miller WH Jr and Evans RM: Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 391: 811-814, 1998.
-
(1998)
Nature
, vol.391
, pp. 811-814
-
-
Lin, R.J.1
Nagy, L.2
Inoue, S.3
Shao, W.4
Miller Jr., W.H.5
Evans, R.M.6
-
3
-
-
0037974596
-
Treatment of acute promyelocytic leukemia with ATRA and As2O3: A model of molecular target-based cancer therapy
-
Fang J, Chen SJ, Tong JH, Wang ZG, Chen GQ and Chen Z: Treatment of acute promyelocytic leukemia with ATRA and As2O3: a model of molecular target-based cancer therapy. Cancer Biol Ther 1: 614-620, 2002.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 614-620
-
-
Fang, J.1
Chen, S.J.2
Tong, J.H.3
Wang, Z.G.4
Chen, G.Q.5
Chen, Z.6
-
4
-
-
41949111045
-
Acute promyelocytic leukemia: From highly fatal to highly curable
-
Wang ZY and Chen Z: Acute promyelocytic leukemia: from highly fatal to highly curable. Blood 111: 2505-2515, 2008.
-
(2008)
Blood
, vol.111
, pp. 2505-2515
-
-
Wang, Z.Y.1
Chen, Z.2
-
5
-
-
0033827097
-
Mechanisms of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells
-
Zhang JW, Wang JY, Chen SJ and Chen Z: Mechanisms of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells. J Biosci 25: 275-284, 2000.
-
(2000)
J Biosci
, vol.25
, pp. 275-284
-
-
Zhang, J.W.1
Wang, J.Y.2
Chen, S.J.3
Chen, Z.4
-
6
-
-
0033561797
-
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
-
Melnick A and Licht JD: Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93: 3167-3215, 1999.
-
(1999)
Blood
, vol.93
, pp. 3167-3215
-
-
Melnick, A.1
Licht, J.D.2
-
8
-
-
70350621606
-
Comparison of clinical outcomes of patients with relapsed acute promyelocytic leukemia induced with arsenic trioxide and consolidated with either an autologous stem cell transplant or an arsenic trioxide-based regimen
-
Thirugnanam R, George B, Chendamarai E, Lakshmi KM, Balasubramanian P, Viswabandya A, Srivastava A, Chandy M and Mathews V: Comparison of clinical outcomes of patients with relapsed acute promyelocytic leukemia induced with arsenic trioxide and consolidated with either an autologous stem cell transplant or an arsenic trioxide-based regimen. Biol Blood Marrow Transplant 15: 1479-1484, 2009.
-
(2009)
Biol Blood Marrow Transplant
, vol.15
, pp. 1479-1484
-
-
Thirugnanam, R.1
George, B.2
Chendamarai, E.3
Lakshmi, K.M.4
Balasubramanian, P.5
Viswabandya, A.6
Srivastava, A.7
Chandy, M.8
Mathews, V.9
-
9
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Göttlicher M, Minucci S, Zhu P, Krämer OH, Schimpf A, Giavara S, Sleeman JP, Lo Coco F, Nervi C, Pelicci PG and Heinzel T: Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 20: 6969-6978, 2001.
-
(2001)
EMBO J
, vol.20
, pp. 6969-6978
-
-
Göttlicher, M.1
Minucci, S.2
Zhu, P.3
Krämer, O.H.4
Schimpf, A.5
Giavara, S.6
Sleeman, J.P.7
Lo Coco, F.8
Nervi, C.9
Pelicci, P.G.10
Heinzel, T.11
-
10
-
-
79751528245
-
Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia
-
Quintás-Cardama A, Santos FP and Garcia-Manero G: Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia. Leukemia 25: 226-235, 2011.
-
(2011)
Leukemia
, vol.25
, pp. 226-235
-
-
Quintás-Cardama, A.1
Santos, F.P.2
Garcia-Manero, G.3
-
12
-
-
34547652768
-
Downregulation of c-Myc is critical for valproic acid-induced growth arrest and myeloid differentiation of acute myeloid leukemia
-
Cheng YC, Lin H, Huang MJ, Chow JM, Lin S and Liu HE: Downregulation of c-Myc is critical for valproic acid-induced growth arrest and myeloid differentiation of acute myeloid leukemia. Leuk Res 31: 1403-1411, 2007.
-
(2007)
Leuk Res
, vol.31
, pp. 1403-1411
-
-
Cheng, Y.C.1
Lin, H.2
Huang, M.J.3
Chow, J.M.4
Lin, S.5
Liu, H.E.6
-
13
-
-
33748997409
-
Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia
-
Cimino G, Lo-Coco F, Fenu S, Travaglini L, Finolezzi E, Mancini M, Nanni M, Careddu A, Fazi F, Padula F, Fiorini R, Spiriti MA, Petti MC, Venditti A, Amadori S, Mandelli F, Pelicci PG and Nervi C: Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia. Cancer Res 66: 8903-8911, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 8903-8911
-
-
Cimino, G.1
Lo-Coco, F.2
Fenu, S.3
Travaglini, L.4
Finolezzi, E.5
Mancini, M.6
Nanni, M.7
Careddu, A.8
Fazi, F.9
Padula, F.10
Fiorini, R.11
Spiriti, M.A.12
Petti, M.C.13
Venditti, A.14
Amadori, S.15
Mandelli, F.16
Pelicci, P.G.17
Nervi, C.18
-
14
-
-
29744454120
-
The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia
-
Kuendgen A, Schmid M, Schlenk R, Knipp S, Hildebrandt B, Steidl C, Germing U, Haas R, Dohner H and Gattermann N: The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia. Cancer 106: 112-119, 2006.
-
(2006)
Cancer
, vol.106
, pp. 112-119
-
-
Kuendgen, A.1
Schmid, M.2
Schlenk, R.3
Knipp, S.4
Hildebrandt, B.5
Steidl, C.6
Germing, U.7
Haas, R.8
Dohner, H.9
Gattermann, N.10
-
15
-
-
4444309863
-
Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid
-
Kuendgen A, Strupp C, Aivado M, Bernhardt A, Hildebrandt B, Haas R, Germing U and Gattermann N: Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid. Blood 104: 1266-1269, 2004.
-
(2004)
Blood
, vol.104
, pp. 1266-1269
-
-
Kuendgen, A.1
Strupp, C.2
Aivado, M.3
Bernhardt, A.4
Hildebrandt, B.5
Haas, R.6
Germing, U.7
Gattermann, N.8
-
16
-
-
0242389807
-
C/EBPbeta: A major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells
-
Duprez E, Wagner K, Koch H and Tenen DG: C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells. EMBO J 22: 5806-5816, 2003.
-
(2003)
EMBO J
, vol.22
, pp. 5806-5816
-
-
Duprez, E.1
Wagner, K.2
Koch, H.3
Tenen, D.G.4
-
17
-
-
76249123883
-
Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia
-
Guibal FC, Alberich-Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, Zhang P, Santana-Lemos BA, Neuberg D, Wagers AJ, Rego EM and Tenen DG: Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia. Blood 114: 5415-5425, 2009.
-
(2009)
Blood
, vol.114
, pp. 5415-5425
-
-
Guibal, F.C.1
Alberich-Jorda, M.2
Hirai, H.3
Ebralidze, A.4
Levantini, E.5
Di Ruscio, A.6
Zhang, P.7
Santana-Lemos, B.A.8
Neuberg, D.9
Wagers, A.J.10
Rego, E.M.11
Tenen, D.G.12
-
18
-
-
33645734361
-
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression
-
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U and Tenen DG: ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression. Blood 107: 3330-3338, 2006.
-
(2006)
Blood
, vol.107
, pp. 3330-3338
-
-
Mueller, B.U.1
Pabst, T.2
Fos, J.3
Petkovic, V.4
Fey, M.F.5
Asou, N.6
Buergi, U.7
Tenen, D.G.8
-
19
-
-
0032694990
-
CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment
-
Park DJ, Chumakov AM, Vuong PT, Chih DY, Gombart AF, Miller WH Jr and Koeffler HP: CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment. J Clin Invest 103: 1399-1408, 1999.
-
(1999)
J Clin Invest
, vol.103
, pp. 1399-1408
-
-
Park, D.J.1
Chumakov, A.M.2
Vuong, P.T.3
Chih, D.Y.4
Gombart, A.F.5
Miller Jr., W.H.6
Koeffler, H.P.7
-
20
-
-
12844280533
-
Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis
-
Rosmarin AG, Yang Z and Res es KK: Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis. Exp Hematol 33: 131-143, 2005.
-
(2005)
Exp Hematol
, vol.33
, pp. 131-143
-
-
Rosmarin, A.G.1
Yang, Z.A.R.E.K.K.2
-
21
-
-
78549263680
-
C/EBPbeta and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro
-
Zhang K, Li J, Meng W, Xing H and Yang Y: C/EBPbeta and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro. Int J Hematol 92: 571-578, 2010.
-
(2010)
Int J Hematol
, vol.92
, pp. 571-578
-
-
Zhang, K.1
Li, J.2
Meng, W.3
Xing, H.4
Yang, Y.5
-
22
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG: Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 3: 89-101, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
23
-
-
81855194085
-
Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes
-
Yoshino Y, Yuan B, Kaise T, Takeichi M, Tanaka S, Hirano T, Kroetz DL and Toyoda H: Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes. Toxicol Appl Pharmacol 257: 198-208, 2011.
-
(2011)
Toxicol Appl Pharmacol
, vol.257
, pp. 198-208
-
-
Yoshino, Y.1
Yuan, B.2
Kaise, T.3
Takeichi, M.4
Tanaka, S.5
Hirano, T.6
Kroetz, D.L.7
Toyoda, H.8
-
24
-
-
84866442648
-
Granulocyte colony-stimulating factor potentiates differentiation induction by all-trans retinoic acid and arsenic trioxide and enhances arsenic uptake in the acute promyelocytic leukemia cell line HT93A
-
Iriyama N, Yuan B, Hatta Y, Horikoshi A, Yoshino Y, Toyoda H, Aizawa S and Takeuchi J: Granulocyte colony-stimulating factor potentiates differentiation induction by all-trans retinoic acid and arsenic trioxide and enhances arsenic uptake in the acute promyelocytic leukemia cell line HT93A. Oncol Rep 28: 1875-1882, 2012.
-
(2012)
Oncol Rep
, vol.28
, pp. 1875-1882
-
-
Iriyama, N.1
Yuan, B.2
Hatta, Y.3
Horikoshi, A.4
Yoshino, Y.5
Toyoda, H.6
Aizawa, S.7
Takeuchi, J.8
-
25
-
-
59649127568
-
Direct contribution of inducible nitric oxide synthase expression to apoptosis induction in primary smooth chorion trophoblast cells of human fetal membrane tissues
-
Yuan B, Ohyama K, Takeichi M and Toyoda H: Direct contribution of inducible nitric oxide synthase expression to apoptosis induction in primary smooth chorion trophoblast cells of human fetal membrane tissues. Int J Biochem Cell Biol 41: 1062-1069, 2009.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1062-1069
-
-
Yuan, B.1
Ohyama, K.2
Takeichi, M.3
Toyoda, H.4
-
26
-
-
0032879920
-
Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia: A new approach to anti-leukemia therapy
-
Kosugi H, Towatari M, Hatano S, Kitamura K, Kiyoi H, Kinoshita T, Tanimoto M, Murate T, Kawashima K, Saito H and Naoe T: Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia: a new approach to anti-leukemia therapy. Leukemia 13: 1316-1324, 1999.
-
(1999)
Leukemia
, vol.13
, pp. 1316-1324
-
-
Kosugi, H.1
Towatari, M.2
Hatano, S.3
Kitamura, K.4
Kiyoi, H.5
Kinoshita, T.6
Tanimoto, M.7
Murate, T.8
Kawashima, K.9
Saito, H.10
Naoe, T.11
-
27
-
-
0030865680
-
A novel, myeloid transcription factor, C/EBP epsilon, is upregulated during granulocytic, but not monocytic, differentiation
-
Morosetti R, Park DJ, Chumakov AM, Grillier I, Shiohara M, Gombart AF, Nakamaki T, Weinberg K and Koeffler HP: A novel, myeloid transcription factor, C/EBP epsilon, is upregulated during granulocytic, but not monocytic, differentiation. Blood 90: 2591-2600, 1997.
-
(1997)
Blood
, vol.90
, pp. 2591-2600
-
-
Morosetti, R.1
Park, D.J.2
Chumakov, A.M.3
Grillier, I.4
Shiohara, M.5
Gombart, A.F.6
Nakamaki, T.7
Weinberg, K.8
Koeffler, H.P.9
-
28
-
-
0037974780
-
Granulocyte colony-stimulating factor-induced terminal maturation of human myeloid cells is specifically associated with up-regulation of receptor-mediated function and CD10 expression
-
Inazawa Y, Saeki K and Yuo A: Granulocyte colony-stimulating factor-induced terminal maturation of human myeloid cells is specifically associated with up-regulation of receptor-mediated function and CD10 expression. Int J Hematol 77: 142-151, 2003.
-
(2003)
Int J Hematol
, vol.77
, pp. 142-151
-
-
Inazawa, Y.1
Saeki, K.2
Yuo, A.3
-
29
-
-
10744227258
-
Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation
-
Zhao Q, Tao J, Zhu Q, Jia PM, Dou AX, Li X, Cheng F, Waxman S, Chen GQ, Chen SJ, Lanotte M, Chen Z and Tong JH: Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation. Leukemia 18: 285-292, 2004.
-
(2004)
Leukemia
, vol.18
, pp. 285-292
-
-
Zhao, Q.1
Tao, J.2
Zhu, Q.3
Jia, P.M.4
Dou, A.X.5
Li, X.6
Cheng, F.7
Waxman, S.8
Chen, G.Q.9
Chen, S.J.10
Lanotte, M.11
Chen, Z.12
Tong, J.H.13
-
30
-
-
41349113805
-
Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression
-
Zhang K, Guo QL, You QD, Yang Y, Zhang HW, Yang L, Gu HY, Qi Q, Tan Z and Wang X: Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. Cancer Sci 99: 689-695, 2008.
-
(2008)
Cancer Sci
, vol.99
, pp. 689-695
-
-
Zhang, K.1
Guo, Q.L.2
You, Q.D.3
Yang, Y.4
Zhang, H.W.5
Yang, L.6
Gu, H.Y.7
Qi, Q.8
Tan, Z.9
Wang, X.10
-
31
-
-
0036201888
-
Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways
-
Kawagoe R, Kawagoe H and Sano K: Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways. Leuk Res 26: 495-502, 2002.
-
(2002)
Leuk Res
, vol.26
, pp. 495-502
-
-
Kawagoe, R.1
Kawagoe, H.2
Sano, K.3
-
32
-
-
84863781700
-
Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL
-
Leiva M, Moretti S, Soilihi H, Pallavicini I, Peres L, Mercurio C, Dal Zuffo R, Minucci S and de Thé H: Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL. Leukemia 26: 1630-1637, 2012.
-
(2012)
Leukemia
, vol.26
, pp. 1630-1637
-
-
Leiva, M.1
Moretti, S.2
Soilihi, H.3
Pallavicini, I.4
Peres, L.5
Mercurio, C.6
Dal Zuffo, R.7
Minucci, S.8
De Thé, H.9
-
33
-
-
33745815657
-
Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells
-
Deubzer H, Busche B, Rönndahl G, Eikel D, Michaelis M, Cinatl J, Schulze S, Nau H and Witt O: Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells. Leuk Res 30: 1167-1175, 2006.
-
(2006)
Leuk Res
, vol.30
, pp. 1167-1175
-
-
Deubzer, H.1
Busche, B.2
Rönndahl, G.3
Eikel, D.4
Michaelis, M.5
Cinatl, J.6
Schulze, S.7
Nau, H.8
Witt, O.9
-
34
-
-
84859487538
-
Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically
-
Zapotocky M, Mejstrikova E, Smetana K, Stary J, Trka J and Starkova J: Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically. Cancer Lett 319: 144-153, 2012.
-
(2012)
Cancer Lett
, vol.319
, pp. 144-153
-
-
Zapotocky, M.1
Mejstrikova, E.2
Smetana, K.3
Stary, J.4
Trka, J.5
Starkova, J.6
-
35
-
-
44349166602
-
PML targeting eradicates quiescent leukaemia-initiating cells
-
Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J and Pandolfi PP: PML targeting eradicates quiescent leukaemia-initiating cells. Nature 453: 1072-1078, 2008.
-
(2008)
Nature
, vol.453
, pp. 1072-1078
-
-
Ito, K.1
Bernardi, R.2
Morotti, A.3
Matsuoka, S.4
Saglio, G.5
Ikeda, Y.6
Rosenblatt, J.7
Avigan, D.E.8
Teruya-Feldstein, J.9
Pandolfi, P.P.10
-
36
-
-
84886159783
-
Application of arsenic trioxide therapy for patients with leukemia
-
Sun H (ed). John Wiley & Sons, Ltd., Chichester
-
Yuan B, Yoshino Y, Kaise T and Toyoda H: Application of arsenic trioxide therapy for patients with leukemia. In: Biological Chemistry of Arsenic, Antimony and Bismuth. Sun H (ed). John Wiley & Sons, Ltd., Chichester, pp263-292, 2011.
-
(2011)
Biological Chemistry of Arsenic, Antimony and Bismuth
, pp. 263-292
-
-
Yuan, B.1
Yoshino, Y.2
Kaise, T.3
Toyoda, H.4
|