Hepatotoxic constituents and toxicological mechanism of Xanthium strumarium L. fruits

Journal of Ethnopharmacology

Volumn 152, Issue 2, 2014, Pages 272-282

  Xue, Li Ming ^a,b   Zhang, Qiao Yan ^a   Han, Ping ^c   Jiang, Yi Ping ^a   Yan, Rong Di ^d   Wang, Yang ^a   Rahman, Khalid ^e   Jia, Min ^a   Han, Ting ^a   Qin, Lu Ping ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI MUNICIPAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^d AFFILIATED HOSPITAL OF SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^e LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

1H NMR; Hepatotoxicity; Metabonomics; Xanthium strumarium L.

Indexed keywords

2 OXO GLUTAMATE; 4' DESULPHATE ATRACTYLOSIDE; ACETIC ACID; ACETONE; ATRACTYLOSIDE; CARBOXYATRACTYLOSIDE; CHINESE DRUG; CHOLINE; CITRIC ACID; DIMETHYLAMINE; DIMETHYLGLYCINE; GLUCOSE; GLUTAMIC ACID; GLYCINE; HIPPURIC ACID; LACTATE DEHYDROGENASE; LACTIC ACID; METHYLAMINE; PHENYLALANINE; PLANT EXTRACT; SUCCINIC ACID; TRYPTOPHAN; UNCLASSIFIED DRUG; VALINE; XANTHIUM STRUMARIUM EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FRUIT; HISTOPATHOLOGY; LIVER TOXICITY; NONHUMAN; ORGAN WEIGHT; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; XANTHIUM STRUMARIUM;

RATTUS; XANTHIUM STRUMARIUM;

(1)H NMR; HEPATOTOXICITY; METABONOMICS; XANTHIUM STRUMARIUM L.;

ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; FRUIT; HUMANS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEDICINE, CHINESE TRADITIONAL; METABOLOMICS; MULTIVARIATE ANALYSIS; PLANT EXTRACTS; RATS; RATS, WISTAR; XANTHIUM;

EID: 84896724289     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.12.024     Document Type: Article

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