메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MESSENGER RNA; MICRORNA 146A; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

EID: 84896709722     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079926     Document Type: Article
Times cited : (111)

References (56)
  • 1
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 2
    • 58149240312 scopus 로고    scopus 로고
    • Association between high miR-211 microRNA expression and the poor prognosis of oral carcinoma
    • Chang KW, Liu CJ, Chu TH, Cheng HW, Hung PS, et al. (2008) Association between high miR-211 microRNA expression and the poor prognosis of oral carcinoma. J Dent Res 87: 1063-1068.
    • (2008) J Dent Res , vol.87 , pp. 1063-1068
    • Chang, K.W.1    Liu, C.J.2    Chu, T.H.3    Cheng, H.W.4    Hung, P.S.5
  • 3
    • 76749131605 scopus 로고    scopus 로고
    • miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma
    • Liu CJ, Tsai MM, Hung PS, Kao SY, Liu TY, et al. (2010) miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma. Cancer Res 70: 1635-1644.
    • (2010) Cancer Res , vol.70 , pp. 1635-1644
    • Liu, C.J.1    Tsai, M.M.2    Hung, P.S.3    Kao, S.Y.4    Liu, T.Y.5
  • 4
    • 53349153323 scopus 로고    scopus 로고
    • IFN-induced protein with tetratricopeptide repeats 2 inhibits migration activity and increases survival of oral squamous cell carcinoma
    • Lai KC, Chang KW, Liu CJ, Kao SY, Lee TC (2008) IFN-induced protein with tetratricopeptide repeats 2 inhibits migration activity and increases survival of oral squamous cell carcinoma. Mol Cancer Res 6: 1431-1439.
    • (2008) Mol Cancer Res , vol.6 , pp. 1431-1439
    • Lai, K.C.1    Chang, K.W.2    Liu, C.J.3    Kao, S.Y.4    Lee, T.C.5
  • 5
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappaB: Players, pathways, perspectives
    • Gilmore TD (2006) Introduction to NF-kappaB: players, pathways, perspectives. Oncogene 25: 6680-6684.
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 7
    • 0442323562 scopus 로고    scopus 로고
    • NF-kappaB: Tumor promoter or suppressor?
    • Perkins ND (2004) NF-kappaB: tumor promoter or suppressor? Trends Cell Biol 14: 64-69.
    • (2004) Trends Cell Biol , vol.14 , pp. 64-69
    • Perkins, N.D.1
  • 9
    • 33847311819 scopus 로고    scopus 로고
    • MicroRNAs and Immunity: Tiny Players in a Big Field
    • DOI 10.1016/j.immuni.2007.02.005, PII S1074761307001446
    • Taganov KD, Boldin MP, Baltimore D (2007) MicroRNAs and immunity: tiny players in a big field. Immunity 26: 133-137. (Pubitemid 46329443)
    • (2007) Immunity , vol.26 , Issue.2 , pp. 133-137
    • Taganov, K.D.1    Boldin, M.P.2    Baltimore, D.3
  • 10
    • 33847394078 scopus 로고    scopus 로고
    • Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma
    • DOI 10.1038/sj.onc.1209945, PII 1209945
    • Jackson-Bernitsas DG, Ichikawa H, Takada Y, Myers JN, Lin XL, et al. (2007) Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma. Oncogene 26: 1385-1397. (Pubitemid 46340818)
    • (2007) Oncogene , vol.26 , Issue.10 , pp. 1385-1397
    • Jackson-Bernitsas, D.G.1    Ichikawa, H.2    Takada, Y.3    Myers, J.N.4    Lin, X.L.5    Darnay, B.G.6    Chaturvedi, M.M.7    Aggarwal, B.B.8
  • 11
    • 66149140644 scopus 로고    scopus 로고
    • Triggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack
    • Szczepanski MJ, Czystowska M, Szajnik M, Harasymczuk M, Boyiadzis M, et al. (2009) Triggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack. Cancer Res 69: 3105-3113.
    • (2009) Cancer Res , vol.69 , pp. 3105-3113
    • Szczepanski, M.J.1    Czystowska, M.2    Szajnik, M.3    Harasymczuk, M.4    Boyiadzis, M.5
  • 12
    • 65249138193 scopus 로고    scopus 로고
    • MicroRNA-146A contributes to abnormal activation of the type i interferon pathway in human lupus by targeting the key signaling proteins
    • Tang Y, Luo X, Cui H, Ni X, Yuan M, et al. (2009) MicroRNA-146A contributes to abnormal activation of the type i interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum 60: 1065-1075.
    • (2009) Arthritis Rheum , vol.60 , pp. 1065-1075
    • Tang, Y.1    Luo, X.2    Cui, H.3    Ni, X.4    Yuan, M.5
  • 13
    • 84859746790 scopus 로고    scopus 로고
    • MicroRNA miR-146b-5p regulates signal transduction of TGF-beta by repressing SMAD4 in thyroid cancer
    • Geraldo MV, Yamashita AS, Kimura ET (2012) MicroRNA miR-146b-5p regulates signal transduction of TGF-beta by repressing SMAD4 in thyroid cancer. Oncogene 31: 1910-1922.
    • (2012) Oncogene , vol.31 , pp. 1910-1922
    • Geraldo, M.V.1    Yamashita, A.S.2    Kimura, E.T.3
  • 14
    • 84862908996 scopus 로고    scopus 로고
    • Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis
    • Xiao B, Zhu ED, Li N, Lu DS, Li W, et al. (2012) Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. Oncol Rep 27: 559-566.
    • (2012) Oncol Rep , vol.27 , pp. 559-566
    • Xiao, B.1    Zhu, E.D.2    Li, N.3    Lu, D.S.4    Li, W.5
  • 15
    • 79960336510 scopus 로고    scopus 로고
    • Clinical significance of miR-146a in gastric cancer cases
    • Kogo R, Mimori K, Tanaka F, Komune S, Mori M (2011) Clinical significance of miR-146a in gastric cancer cases. Clin Cancer Res 17: 4277-4284.
    • (2011) Clin Cancer Res , vol.17 , pp. 4277-4284
    • Kogo, R.1    Mimori, K.2    Tanaka, F.3    Komune, S.4    Mori, M.5
  • 16
    • 57149092998 scopus 로고    scopus 로고
    • Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb
    • Kuang W, Tan J, Duan Y, Duan J, Wang W, et al. (2009) Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb. Biochem Biophys Res Commun 378: 259-263.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 259-263
    • Kuang, W.1    Tan, J.2    Duan, Y.3    Duan, J.4    Wang, W.5
  • 17
    • 84865183734 scopus 로고    scopus 로고
    • microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer
    • Hou Z, Yin H, Chen C, Dai X, Li X, et al. (2012) microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer. Mol Med Report 6: 501-506.
    • (2012) Mol Med Report , vol.6 , pp. 501-506
    • Hou, Z.1    Yin, H.2    Chen, C.3    Dai, X.4    Li, X.5
  • 18
    • 77954452779 scopus 로고    scopus 로고
    • CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells
    • Rom S, Rom I, Passiatore G, Pacifici M, Radhakrishnan S, et al. (2010) CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells. FASEB J 24: 2292-2300.
    • (2010) FASEB J , vol.24 , pp. 2292-2300
    • Rom, S.1    Rom, I.2    Passiatore, G.3    Pacifici, M.4    Radhakrishnan, S.5
  • 19
    • 84864011802 scopus 로고    scopus 로고
    • MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4
    • He Y, Huang C, Sun X, Long XR, Lv XW, et al. (2012) MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4. Cell Signal 24: 1923-1930.
    • (2012) Cell Signal , vol.24 , pp. 1923-1930
    • He, Y.1    Huang, C.2    Sun, X.3    Long, X.R.4    Lv, X.W.5
  • 20
    • 40449131878 scopus 로고    scopus 로고
    • Loss of mir-146a function in hormone-refractory prostate cancer
    • DOI 10.1261/rna.874808
    • Lin SL, Chiang A, Chang D, Ying SY (2008) Loss of mir-146a function in hormone-refractory prostate cancer. Rna 14: 417-424. (Pubitemid 351397806)
    • (2008) RNA , vol.14 , Issue.3 , pp. 417-424
    • Lin, S.-L.1    Chiang, A.2    Chang, D.3    Ying, S.-Y.4
  • 25
    • 84862895814 scopus 로고    scopus 로고
    • Numb regulates glioma stem cell fate and growth by altering epidermal growth factor receptor and skp1-cullin-f-box ubiquitin ligase activity
    • Jiang X, Xing H, Kim TM, Jung Y, Huang W, et al. (2012) Numb regulates glioma stem cell fate and growth by altering epidermal growth factor receptor and skp1-cullin-f-box ubiquitin ligase activity. Stem Cells 30: 1313-1326.
    • (2012) Stem Cells , vol.30 , pp. 1313-1326
    • Jiang, X.1    Xing, H.2    Kim, T.M.3    Jung, Y.4    Huang, W.5
  • 27
    • 84856264859 scopus 로고    scopus 로고
    • IKKalpha activation of NOTCH links tumorigenesis via FOXA2 suppression
    • Liu M, Lee DF, Chen CT, Yen CJ, Li LY, et al. (2012) IKKalpha activation of NOTCH links tumorigenesis via FOXA2 suppression. Mol Cell 45: 171-184.
    • (2012) Mol Cell , vol.45 , pp. 171-184
    • Liu, M.1    Lee, D.F.2    Chen, C.T.3    Yen, C.J.4    Li, L.Y.5
  • 28
    • 49749107841 scopus 로고    scopus 로고
    • Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth
    • Wang X, Tang S, Le SY, Lu R, Rader JS, et al. (2008) Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS ONE 3: e2557.
    • (2008) PLoS ONE , vol.3
    • Wang, X.1    Tang, S.2    Le, S.Y.3    Lu, R.4    Rader, J.S.5
  • 29
    • 57349100487 scopus 로고    scopus 로고
    • MicroRNA alterations in head and neck squamous cell carcinoma
    • Chang SS, Jiang WW, Smith I, Poeta LM, Begum S, et al. (2008) MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 123: 2791-2797.
    • (2008) Int J Cancer , vol.123 , pp. 2791-2797
    • Chang, S.S.1    Jiang, W.W.2    Smith, I.3    Poeta, L.M.4    Begum, S.5
  • 30
    • 84859982208 scopus 로고    scopus 로고
    • Association between the rs2910164 polymorphism in pre-mir-146a and oral carcinoma progression
    • Hung PS, Chang KW, Kao SY, Chu TH, Liu CJ, et al. (2012) Association between the rs2910164 polymorphism in pre-mir-146a and oral carcinoma progression. Oral Oncol 48: 404-408.
    • (2012) Oral Oncol , vol.48 , pp. 404-408
    • Hung, P.S.1    Chang, K.W.2    Kao, S.Y.3    Chu, T.H.4    Liu, C.J.5
  • 31
    • 50249103246 scopus 로고    scopus 로고
    • MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma
    • Chen YT, Kitabayashi N, Zhou XK, Fahey TJ, 3rd, Scognamiglio T (2008) MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. Mod Pathol 21: 1139-1146.
    • (2008) Mod Pathol , vol.21 , pp. 1139-1146
    • Chen, Y.T.1    Kitabayashi, N.2    Zhou, X.K.3    Fahey III, T.J.4    Scognamiglio, T.5
  • 32
    • 77952838399 scopus 로고    scopus 로고
    • Signatures of microRNAs and selected microRNA target genes in human melanoma
    • Philippidou D, Schmitt M, Moser D, Margue C, Nazarov PV, et al. (2010) Signatures of microRNAs and selected microRNA target genes in human melanoma. Cancer Res 70: 4163-4173.
    • (2010) Cancer Res , vol.70 , pp. 4163-4173
    • Philippidou, D.1    Schmitt, M.2    Moser, D.3    Margue, C.4    Nazarov, P.V.5
  • 33
    • 70450179727 scopus 로고    scopus 로고
    • Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma
    • Cervigne NK, Reis PP, Machado J, Sadikovic B, Bradley G, et al. (2009) Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. Hum Mol Genet 18: 4818-4829.
    • (2009) Hum Mol Genet , vol.18 , pp. 4818-4829
    • Cervigne, N.K.1    Reis, P.P.2    Machado, J.3    Sadikovic, B.4    Bradley, G.5
  • 34
    • 67651002796 scopus 로고    scopus 로고
    • MicroRNA classifiers for predicting prognosis of squamous cell lung cancer
    • Raponi M, Dossey L, Jatkoe T, Wu X, Chen G, et al. (2009) MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res 69: 5776-5783.
    • (2009) Cancer Res , vol.69 , pp. 5776-5783
    • Raponi, M.1    Dossey, L.2    Jatkoe, T.3    Wu, X.4    Chen, G.5
  • 35
    • 56049092548 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma
    • Xu T, Zhu Y, Wei QK, Yuan Y, Zhou F, et al. (2008) A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 29: 2126-2131.
    • (2008) Carcinogenesis , vol.29 , pp. 2126-2131
    • Xu, T.1    Zhu, Y.2    Wei, Q.K.3    Yuan, Y.4    Zhou, F.5
  • 36
    • 60549090858 scopus 로고    scopus 로고
    • Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis
    • Hurst DR, Edmonds MD, Scott GK, Benz CC, Vaidya KS, et al. (2009) Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res 69: 1279-1283.
    • (2009) Cancer Res , vol.69 , pp. 1279-1283
    • Hurst, D.R.1    Edmonds, M.D.2    Scott, G.K.3    Benz, C.C.4    Vaidya, K.S.5
  • 37
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J, et al. (2008) Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene.
    • (2008) Oncogene
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5
  • 38
    • 76749152907 scopus 로고    scopus 로고
    • miR-146a suppresses invasion of pancreatic cancer cells
    • Li Y, Vandenboom TG, 2nd, Wang Z, Kong D, Ali S, et al. (2010) miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res 70: 1486-1495.
    • (2010) Cancer Res , vol.70 , pp. 1486-1495
    • Li, Y.1    Vandenboom II, T.G.2    Wang, Z.3    Kong, D.4    Ali, S.5
  • 39
    • 73849121794 scopus 로고    scopus 로고
    • Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype
    • Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, et al. (2010) Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype. Nat Med 16: 49-58.
    • (2010) Nat Med , vol.16 , pp. 49-58
    • Starczynowski, D.T.1    Kuchenbauer, F.2    Argiropoulos, B.3    Sung, S.4    Morin, R.5
  • 40
    • 77950466208 scopus 로고    scopus 로고
    • Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer
    • Liu CJ, Kao SY, Tu HF, Tsai MM, Chang KW, et al. (2010) Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer. Oral Dis 16: 360-364.
    • (2010) Oral Dis , vol.16 , pp. 360-364
    • Liu, C.J.1    Kao, S.Y.2    Tu, H.F.3    Tsai, M.M.4    Chang, K.W.5
  • 41
    • 23244466456 scopus 로고    scopus 로고
    • Areca (betel) nut extract activates mitogen-activated protein kinases and NF-kappaB in oral keratinocytes
    • DOI 10.1002/ijc.21104
    • Lin SC, Lu SY, Lee SY, Lin CY, Chen CH, et al. (2005) Areca (betel) nut extract activates mitogen-activated protein kinases and NF-kappaB in oral keratinocytes. Int J Cancer 116: 526-535. (Pubitemid 41099188)
    • (2005) International Journal of Cancer , vol.116 , Issue.4 , pp. 526-535
    • Lin, S.-C.1    Lu, S.-Y.2    Lee, S.-Y.3    Lin, C.-Y.4    Chen, C.-H.5    Chang, K.-W.6
  • 42
    • 33745600572 scopus 로고    scopus 로고
    • Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte
    • Lu SY, Chang KW, Liu CJ, Tseng YH, Lu HH, et al. (2006) Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte. Carcinogenesis 27: 1273-1284.
    • (2006) Carcinogenesis , vol.27 , pp. 1273-1284
    • Lu, S.Y.1    Chang, K.W.2    Liu, C.J.3    Tseng, Y.H.4    Lu, H.H.5
  • 43
    • 58149235288 scopus 로고    scopus 로고
    • Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells
    • Lu HH, Liu CJ, Liu TY, Kao SY, Lin SC, et al. (2008) Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells. J Dent Res 87: 1069-1074.
    • (2008) J Dent Res , vol.87 , pp. 1069-1074
    • Lu, H.H.1    Liu, C.J.2    Liu, T.Y.3    Kao, S.Y.4    Lin, S.C.5
  • 44
    • 77749285708 scopus 로고    scopus 로고
    • miR-146a induces differentiation of periodontal ligament cells
    • Hung PS, Chen FC, Kuang SH, Kao SY, Lin SC, et al. (2010) miR-146a induces differentiation of periodontal ligament cells. J Dent Res 89: 252-257.
    • (2010) J Dent Res , vol.89 , pp. 252-257
    • Hung, P.S.1    Chen, F.C.2    Kuang, S.H.3    Kao, S.Y.4    Lin, S.C.5
  • 45
    • 38949100425 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-5 (IGFBP-5) suppresses the tumourigenesis of head and neck squamous cell carcinoma
    • Hung PS, Kao SY, Shih YH, Chiou SH, Liu CJ, et al. (2008) Insulin-like growth factor binding protein-5 (IGFBP-5) suppresses the tumourigenesis of head and neck squamous cell carcinoma. J Pathol 214: 368-376.
    • (2008) J Pathol , vol.214 , pp. 368-376
    • Hung, P.S.1    Kao, S.Y.2    Shih, Y.H.3    Chiou, S.H.4    Liu, C.J.5
  • 46
    • 81155126038 scopus 로고    scopus 로고
    • Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer
    • Patel V, Marsh CA, Dorsam RT, Mikelis CM, Masedunskas A, et al. (2011) Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer. Cancer Res 71: 7103-7112.
    • (2011) Cancer Res , vol.71 , pp. 7103-7112
    • Patel, V.1    Marsh, C.A.2    Dorsam, R.T.3    Mikelis, C.M.4    Masedunskas, A.5
  • 48
    • 58049170793 scopus 로고    scopus 로고
    • MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes
    • Pichler K, Schneider G, Grassmann R (2008) MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes. Retrovirology 5: 100.
    • (2008) Retrovirology , vol.5 , pp. 100
    • Pichler, K.1    Schneider, G.2    Grassmann, R.3
  • 49
    • 80053389114 scopus 로고    scopus 로고
    • TRAF6 is an amplified oncogene bridging the RAS and NF-kappaB pathways in human lung cancer
    • Starczynowski DT, Lockwood WW, Delehouzee S, Chari R, Wegrzyn J, et al. (2011) TRAF6 is an amplified oncogene bridging the RAS and NF-kappaB pathways in human lung cancer. J Clin Invest 121: 4095-4105.
    • (2011) J Clin Invest , vol.121 , pp. 4095-4105
    • Starczynowski, D.T.1    Lockwood, W.W.2    Delehouzee, S.3    Chari, R.4    Wegrzyn, J.5
  • 50
    • 79958698402 scopus 로고    scopus 로고
    • TRAF6 ubiquitinates TGFbeta type I receptor to promote its cleavage and nuclear translocation in cancer
    • Mu Y, Sundar R, Thakur N, Ekman M, Gudey SK, et al. (2011) TRAF6 ubiquitinates TGFbeta type I receptor to promote its cleavage and nuclear translocation in cancer. Nat Commun 2: 330.
    • (2011) Nat Commun , vol.2 , pp. 330
    • Mu, Y.1    Sundar, R.2    Thakur, N.3    Ekman, M.4    Gudey, S.K.5
  • 51
    • 77953563697 scopus 로고    scopus 로고
    • The code within the code: MicroRNAs target coding regions
    • Forman JJ, Coller HA (2010) The code within the code: microRNAs target coding regions. Cell Cycle 9: 1533-1541.
    • (2010) Cell Cycle , vol.9 , pp. 1533-1541
    • Forman, J.J.1    Coller, H.A.2
  • 52
    • 67649623162 scopus 로고    scopus 로고
    • Symmetric division and expression of its regulatory gene Numb in human cervical squamous carcinoma cells
    • Chen H, Chen X, Ye F, Lu W, Xie X (2009) Symmetric division and expression of its regulatory gene Numb in human cervical squamous carcinoma cells. Pathobiology 76: 149-154.
    • (2009) Pathobiology , vol.76 , pp. 149-154
    • Chen, H.1    Chen, X.2    Ye, F.3    Lu, W.4    Xie, X.5
  • 53
    • 80052177544 scopus 로고    scopus 로고
    • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
    • Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, et al. (2011) Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 333: 1154-1157.
    • (2011) Science , vol.333 , pp. 1154-1157
    • Agrawal, N.1    Frederick, M.J.2    Pickering, C.R.3    Bettegowda, C.4    Chang, K.5
  • 54
    • 80052158097 scopus 로고    scopus 로고
    • The mutational landscape of head and neck squamous cell carcinoma
    • Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, et al. (2011) The mutational landscape of head and neck squamous cell carcinoma. Science 333: 1157-1160.
    • (2011) Science , vol.333 , pp. 1157-1160
    • Stransky, N.1    Egloff, A.M.2    Tward, A.D.3    Kostic, A.D.4    Cibulskis, K.5
  • 55
    • 79954447907 scopus 로고    scopus 로고
    • Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003)
    • Chung CH, Dignam JJ, Hammond ME, Klimowicz AC, Petrillo SK, et al. (2011) Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003). J Clin Oncol 29: 1326-1334.
    • (2011) J Clin Oncol , vol.29 , pp. 1326-1334
    • Chung, C.H.1    Dignam, J.J.2    Hammond, M.E.3    Klimowicz, A.C.4    Petrillo, S.K.5
  • 56
    • 69249209681 scopus 로고    scopus 로고
    • Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling
    • Wang Z, Sandiford S, Wu C, Li SS (2009) Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling. EMBO J 28: 2360-2373.
    • (2009) EMBO J , vol.28 , pp. 2360-2373
    • Wang, Z.1    Sandiford, S.2    Wu, C.3    Li, S.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.