The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs

Nucleic Acids Research

Volumn 42, Issue 3, 2014, Pages 2037-2048

  Czudnochowski, Nadine ^a   Ashley, Gary W ^b   Santi, Daniel V ^b   Alian, Akram ^c   Finer Moore, Janet ^a   Stroud, Robert M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ProLynx   (United States)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURIDINE; PROTEIN RLUB; PROTEIN RLUF; PSEUDOURIDINE; SYNTHETASE; TYROSINE; UNCLASSIFIED DRUG; URIDINE;

ARTICLE; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HYDROGEN BOND; MICHAEL ADDITION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN RNA BINDING; RIBOSOME; RNA SEQUENCE; RNA STRUCTURE; RNA TRANSLATION;

APOENZYMES; ARGININE; CATALYTIC DOMAIN; ESCHERICHIA COLI PROTEINS; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RNA, RIBOSOMAL, 23S; SUBSTRATE SPECIFICITY; TYROSINE; URIDINE; WATER;

EID: 84896706255     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt1050     Document Type: Article

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