A conserved aspartate of tRNA pseudouridine synthase is essential for activity and a probable nucleophilic catalyst

Biochemistry

Volumn 37, Issue 1, 1998, Pages 344-351

  Huang, Lixuan ^a   Pookanjanatavip, Manee ^b   Gu, Xiangrong ^c   Santi, Daniel V ^c  

^a DUPONT COMPANY   (United States)

^b CHIANG MAI UNIVERSITY   (Thailand)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; ASPARTIC ACID; FLUOROURACIL; MUTANT PROTEIN; PSEUDOURIDINE; TRANSFER RNA;

ARTICLE; CATALYST; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ESCHERICHIA COLI; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ASPARTIC ACID; BINDING SITES; CATALYSIS; CLONING, MOLECULAR; CONSERVED SEQUENCE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ESCHERICHIA COLI; FLUOROURACIL; GENETIC VECTORS; INTRAMOLECULAR TRANSFERASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHOSPHORUS RADIOISOTOPES; RNA, TRANSFER, ASP; RNA, TRANSFER, PHE; URACIL;

EID: 0032488657     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971874+     Document Type: Article

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