Gene transfer of integration defective anti-HSV-1 meganuclease to human corneas ex vivo

Gene Therapy

Volumn 21, Issue 3, 2014, Pages 272-281

  Elbadawy, H M ^a   Gailledrat, M ^b   Desseaux, C ^b   Salvalaio, G ^a   Di Iorio, E ^a,c   Ferrari, B ^a   Bertolin, M ^a   Barbaro, V ^a   Parekh, M ^a   Gayon, R ^d   Munegato, D ^c   Franchin, E ^c   Calistri, A ^c   Palu G ^c   Parolin, C ^c   Ponzin, D ^a   Ferrari, S ^a  

^a The Veneto Eye Bank Foundation   (Italy)

^b Arvid Wallgrens Backe 20   (France)

^c UNIVERSITY OF PADOVA   (Italy)

^d Canal Biotech II   (France)

Author keywords

cornea; herpetic keratitis; meganuclease; rAAV2 1 and HSV 1

Indexed keywords

ANTI HERPES SIMPLEX VIRUS 1 MEGANUCLEASE; ENDONUCLEASE; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CORNEA; CORNEA ENDOTHELIUM; CULTURE MEDIUM; ENDOTHELIUM CELL; EX VIVO GENE TRANSFER; EYEBANK; GENE EXPRESSION; GRAFT REJECTION; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; HUMAN TISSUE; INCUBATION TIME; ORGAN CULTURE; PRIORITY JOURNAL; RECURRENT INFECTION; REDUCTION; REPORTER GENE; TRANSGENE; VIRUS LOAD;

ADENO-ASSOCIATED VIRUS; HUMAN HERPESVIRUS 1;

CORNEA; DEOXYRIBONUCLEASE I; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HERPESVIRUS 1, HUMAN; HUMANS; VIRAL PROTEINS;

EID: 84896703171     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2013.82     Document Type: Article

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