CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo: Role of immature dendritic cells

Journal of Virology

Volumn 74, Issue 17, 2000, Pages 8003-8010

  Zhang, Y ^a   Chirmule, N ^a   Gao, G P ^a   Wilson, J ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CD40 ANTIGEN; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; GENE THERAPY; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TRANSGENE; VIRUS RECOMBINANT;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD40; BETA-GALACTOSIDASE; BONE MARROW CELLS; DENDRITIC CELLS; DEPENDOVIRUS; FLUORESCENT ANTIBODY TECHNIQUE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; LAC OPERON; LIGANDS; MICE; MICE, INBRED C57BL; MUSCLE FIBERS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0033882190     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.17.8003-8010.2000     Document Type: Article

References (42)

1. Functional diversity of helper T lymphocytes
2. 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
3. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
4. Dendritic cells and the control of immunity
5. Help for cytotoxic-T-cell responses is mediated by CD40 signaling
6. Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help
7. Biology of adeno-associated virus
8. Induction of immunity to antigens expressed by recombinant adeno-associated virus depends on the route of administration
9. Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL
10. Gene therapy via primary myoblasts: Long-term expression of factor IX protein following transplantation in vivo
11. Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo
12. Recombinant adeno-associated virus for muscle directed gene therapy
13. Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector
14. Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
15. Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer
16. Gene expression following direct injection of DNA into liver
17. Transduction of dendritic cells by DNA viral vectors directs the immune responses to transgene products in muscle fibers
18. Hepatic gene therapy: Persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivo
19. Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein
20. Prospects for the use of adeno-associated virus as a vector for human gene therapy
21. Adeno-associated virus-mediated gene transfer to the brain: Duration and modulation of expression
22. Genetic immunization with adeno-associated virus vectors expressing herpes simplex virus type 2 glycoproteins B and D
23. Developmental regulation of MHC class II transport in mouse dendritic cells
24. Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2
25. Role of tyrosine phosphorylation of a cellular protein in adeno-associated virus 2-mediated transgene expression
26. Phagocytosis of antigens by Langerhans cells in vitro
27. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
28. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
29. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen
30. Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity
31. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas
32. 5 integrin: A co-receptor for adeno-associated virus type 2 infection
33. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
34. Dendritic cell subtypes in mouse lymphoid organs: Cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes
35. Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination
36. Direct gene transfer into mouse muscle in vivo
37. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector
38. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
39. CD40 ligand-dependent T cell activation: Requirement of B7-CD28 signaling through CD40
40. Immunology of gene therapy with adenoviral vectors in mouse skeletal muscle
41. Bifurcated dendritic cell differentiation in vitro from murine lineage phenotype-negative c-kit+ bone marrow hematopoietic progenitor cells
42. Induction of dendritic cell differentiation by granulocyte-macrophage colony-stimulating factor, stem cell factor, and tumor necrosis factor alpha in vitro from lineage phenotypes-negative c-kit+ murine hematopoietic progenitor cells