Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

European Journal of Pharmacology

Volumn 728, Issue 1, 2014, Pages 107-118

  Mantawy, Eman M ^a   El Bakly, Wesam M ^b   Esmat, Ahmed ^a   Badr, Amira M ^a   El Demerdash, Ebtehal ^a  

^a Ain Shams University   (Egypt)

^b AIN SHAMS UNIVERSITY   (Egypt)

Author keywords

Apoptosis; Cardiotoxicity; Chrysin; Doxorubicin; Inflammation; Oxidative stress

Indexed keywords

CASPASE 3; CATALASE; CHRYSIN; CREATINE KINASE MB; CYCLOOXYGENASE 2; CYTOCHROME C; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; LIPID; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC ANTIBIOTIC; ANTIOXIDANT; BIOLOGICAL MARKER; DOXORUBICIN; FLAVONOID; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG MECHANISM; ECHOCARDIOGRAPHY; HEART MUSCLE CONDUCTION DISTURBANCE; HEART MUSCLE INJURY; HEART PROTECTION; HISTOPATHOLOGY; INFLAMMATION; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; ANIMAL; CARDIOMYOPATHIES; CHEMICALLY INDUCED; DRUG EFFECTS; ELECTROCARDIOGRAPHY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; APOPTOSIS; BIOLOGICAL MARKERS; CARDIOMYOPATHIES; DOXORUBICIN; ELECTROCARDIOGRAPHY; FLAVONOIDS; IMMUNOHISTOCHEMISTRY; MALE; NITRIC OXIDE; OXIDATIVE STRESS; RATS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84896698569     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.01.065     Document Type: Article

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