Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-kB signaling pathway

Journal of Pharmacology and Experimental Therapeutics

Volumn 345, Issue 3, 2013, Pages 473-482

  Dou, Wei ^a,b   Zhang, Jingjing ^a   Zhang, Eryun ^a   Sun, Aning ^a   Ding, Lili ^a   Chou, Guixin ^c   Wang, Zhengtao ^a,c   Mani, Sridhar ^b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c Shanghai R and D Center for Standardization of Traditional Chinese Medicines   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHRYSIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PREGNANE X RECEPTOR; RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLITIS; CONTROLLED STUDY; CYCLOOXYGENASE 2 GENE; CYTOKINE PRODUCTION; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; INTERCELLULAR ADHESION MOLECULE 1 GENE; INTERLEUKIN 6 GENE; MONOCYTE CHEMOTACTIC PROTEIN 1 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STOMACH PROTECTION; TUMOR NECROSIS FACTOR ALPHA GENE; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; COLITIS; DEXTRAN SULFATE; FEMALE; FLAVONOIDS; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENES, REPORTER; HUMANS; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; NF-KAPPA B; PEROXIDASE; RECEPTORS, STEROID; RNA; SIGNAL TRANSDUCTION; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84878028859     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.201863     Document Type: Article

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