메뉴 건너뛰기




Volumn 34, Issue 5, 2011, Pages 821-828

Mechanisms underlying the protective effect of eugenol in rats with acute doxorubicin cardiotoxicity

Author keywords

Capsazepine; Cardiotoxicity; Doxorubicin; Eugenol; Rats

Indexed keywords

CALCIUM; CAPSAZEPINE; CASPASE 3; CREATINE KINASE; DOXORUBICIN; EUGENOL; LACTATE DEHYDROGENASE; LIPID; NITRIC OXIDE; VANILLOID RECEPTOR 1 ANTAGONIST;

EID: 79960227106     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0516-2     Document Type: Article
Times cited : (44)

References (31)
  • 1
    • 0035051385 scopus 로고    scopus 로고
    • Anti-genotoxicity of trans-anethole and eugenol in mice
    • DOI 10.1016/S0278-6915(00)00156-3, PII S0278691500001563
    • S. K. Abraham 2001 Anti-genotoxicity of trans-anethole and eugenol in mice Food Chem. Toxicol. 39 493 498 11313116 10.1016/S0278-6915(00)00156-3 1:CAS:528:DC%2BD3MXislGhu7Y%3D (Pubitemid 32323983)
    • (2001) Food and Chemical Toxicology , vol.39 , Issue.5 , pp. 493-498
    • Abraham, S.K.1
  • 3
    • 0034692551 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity of methyleugenol and related congeners-a mechanism of activation for methyleugenol
    • 11006409 1:CAS:528:DC%2BD3cXmslyisb8%3D
    • J. L. Burkey J. M. Sauer C. A. McQueen I. G. Sipes 2000 Cytotoxicity and genotoxicity of methyleugenol and related congeners-a mechanism of activation for methyleugenol Mutat. Res. 453 25 33 11006409 1:CAS:528:DC%2BD3cXmslyisb8%3D
    • (2000) Mutat. Res. , vol.453 , pp. 25-33
    • Burkey, J.L.1    Sauer, J.M.2    McQueen, C.A.3    Sipes, I.G.4
  • 4
    • 35348900146 scopus 로고    scopus 로고
    • Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down-regulation of NF-κB, ERK1/2, and p38 kinase
    • DOI 10.1016/j.ejphar.2007.07.034, PII S0014299907008023
    • C. Y. Choi K. R. Park J.-.H. Lee Y. J. Jeon K. H. Liu S. Oh D. E. Kim S. S. Yea 2007 Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down-regulation of NF-B, ERK1/2, and p38 kinase Eur. J. Pharmacol. 576 151 159 17698059 10.1016/j.ejphar.2007.07.034 1:CAS:528:DC%2BD2sXhtF2ms7nM (Pubitemid 47588244)
    • (2007) European Journal of Pharmacology , vol.576 , Issue.1-3 , pp. 151-159
    • Choi, C.Y.1    Park, K.-R.2    Lee, J.-H.3    Jeon, Y.J.4    Liu, K.-H.5    Oh, S.6    Kim, D.-E.7    Yea, S.S.8
  • 5
    • 33645771759 scopus 로고    scopus 로고
    • Interrelations between oxidative stress and calcineurin in the attenuation of cardiac apoptosis by eugenol
    • 16444593 10.1007/s11010-006-2386-3 1:CAS:528:DC%2BD28XovVCjsA%3D%3D
    • R. Choudhary K. P. Mishra C. Subramanyam 2006 Interrelations between oxidative stress and calcineurin in the attenuation of cardiac apoptosis by eugenol Mol. Cell. Biochem. 283 115 122 16444593 10.1007/s11010-006-2386-3 1:CAS:528:DC%2BD28XovVCjsA%3D%3D
    • (2006) Mol. Cell. Biochem. , vol.283 , pp. 115-122
    • Choudhary, R.1    Mishra, K.P.2    Subramanyam, C.3
  • 6
    • 0024589447 scopus 로고
    • Differential release of calcitonin gene-related peptide and neuropeptide Y form the isolated heart by capsaicin, ischemia, nicotine, bradykinin and ouabain
    • A. Franco-Cereceda A. Saria J. M. Lundberg 1989 Differential release of calcitonin gene-related peptide and neuropeptide Y from the isolated heart by capsaicin, ischaemia, nicotine, bradykinin and ouabain Acta Physiol. Scand. 135 173 187 2784250 10.1111/j.1748-1716.1989.tb08565.x 1:CAS:528:DyaL1MXhsVynsr4%3D (Pubitemid 19058579)
    • (1989) Acta Physiologica Scandinavica , vol.135 , Issue.2 , pp. 173-187
    • Franco-Cereceda, A.1    Saria, A.2    Lundberg, J.M.3
  • 7
    • 41549108389 scopus 로고    scopus 로고
    • Deletion of the mouse α-calcitonin gene-related peptide gene increases the vulnerability of the heart to ischemia-reperfusion injury
    • DOI 10.1152/ajpheart.00749.2007
    • R. Huang A. Karve I. Shah M. C. Bowers D. J. DiPette S. C. Supowit G. S. Abela 2008 Deletion of the mouse alpha-calcitonin gene-related peptide gene increases the vulnerability of the heart to ischemia-reperfusion injury Am. J. Physiol. Heart Circ. Physiol. 294 H1291 H1297 18192222 10.1152/ajpheart.00749. 2007 1:CAS:528:DC%2BD1cXjsFymtrs%3D (Pubitemid 351468726)
    • (2008) American Journal of Physiology - Heart and Circulatory Physiology , vol.294 , Issue.3
    • Huang, R.1    Karve, A.2    Shah, I.3    Bowers, M.C.4    DiPette, D.J.5    Supowit, S.C.6    Abela, G.S.7
  • 8
    • 40849123983 scopus 로고    scopus 로고
    • Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress
    • 18234414 10.1016/j.fct.2007.12.020 1:CAS:528:DC%2BD1cXjs1Kiurg%3D
    • B. Jiang L. Zhang M. Li W. Wu M. Yang J. Wang D.-a. Guo 2008 Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress Food Chem. Toxicol. 46 1510 1515 18234414 10.1016/j.fct.2007. 12.020 1:CAS:528:DC%2BD1cXjs1Kiurg%3D
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 1510-1515
    • Jiang, B.1    Zhang, L.2    Li, M.3    Wu, W.4    Yang, M.5    Wang, J.6    Guo, D.-A.7
  • 9
    • 12844273587 scopus 로고    scopus 로고
    • Antioxidant action of eugenol compounds: Role of metal ion in the inhibition of lipid peroxidation
    • DOI 10.1016/j.fct.2004.11.019, PII S0278691504003497
    • M. Ito K. Murakami M. Yoshino 2005 Antioxidant action of eugenol compounds: role of metal ion in the inhibition of lipid peroxidation Food Chem. Toxicol. 43 461 466 15680683 10.1016/j.fct.2004.11.019 1:CAS:528: DC%2BD2MXos1Sgtw%3D%3D (Pubitemid 40170480)
    • (2005) Food and Chemical Toxicology , vol.43 , Issue.3 , pp. 461-466
    • Ito, M.1    Murakami, K.2    Yoshino, M.3
  • 10
    • 33847644599 scopus 로고    scopus 로고
    • Eugenol [2-methoxy-4-(2-propenyl)phenol] prevents 6-hydroxydopamine- induced dopamine depression and lipid peroxidation inductivity in mouse striatum
    • DOI 10.1248/bpb.30.423
    • H. Kabuto M. Tada M. Kohno 2007 Eugenol [2-methoxy-4-(2-propenyl)phenol] prevents 6-hydroxydopamine-induced dopamine depression and lipid peroxidation inductivity in mouse striatum Biol. Pharm. Bull. 30 423 427 17329831 10.1248/bpb.30.423 1:CAS:528:DC%2BD2sXkvVSnt78%3D (Pubitemid 46355914)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.3 , pp. 423-427
    • Kabuto, H.1    Tada, M.2    Kohno, M.3
  • 11
    • 0026006327 scopus 로고
    • L-type cardiac calcium channels in doxorubicin cardiomyopathy in rats morphological, biochemical, and functional correlations
    • 1645752 10.1172/JCI115241 1:CAS:528:DyaK3MXks1Ciu78%3D
    • E. C. Keung L. Toll M. Ellis R. A. Jensen 1991 L-type cardiac calcium channels in doxorubicin cardiomyopathy in rats morphological, biochemical, and functional correlations J. Clin. Invest. 87 2108 2113 1645752 10.1172/JCI115241 1:CAS:528:DyaK3MXks1Ciu78%3D
    • (1991) J. Clin. Invest. , vol.87 , pp. 2108-2113
    • Keung, E.C.1    Toll, L.2    Ellis, M.3    Jensen, R.A.4
  • 14
    • 33646780258 scopus 로고    scopus 로고
    • Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages
    • 16707845 10.2220/biomedres.27.69
    • W. Li R. Tsubouchi S. Qiao M. Haneda K. Murakami M. Yoshino 2006 Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages Biomed. Res. 27 69 74 16707845 10.2220/biomedres.27.69
    • (2006) Biomed. Res. , vol.27 , pp. 69-74
    • Li, W.1    Tsubouchi, R.2    Qiao, S.3    Haneda, M.4    Murakami, K.5    Yoshino, M.6
  • 15
    • 0037053106 scopus 로고    scopus 로고
    • The cardioprotection of calcitonin gene-related peptide-mediated preconditioning
    • DOI 10.1016/S0014-2999(02)01538-8, PII S0014299902015388
    • Y. J. Li J. Peng 2002 The cardioprotection of calcitonin gene-related peptide-mediated preconditioning Eur. J. Pharmacol. 442 173 177 12065069 10.1016/S0014-2999(02)01538-8 1:CAS:528:DC%2BD38XksVShs7o%3D (Pubitemid 34626191)
    • (2002) European Journal of Pharmacology , vol.442 , Issue.3 , pp. 173-177
    • Li, Y.-J.1    Peng, J.2
  • 16
    • 1642303190 scopus 로고    scopus 로고
    • Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes
    • DOI 10.1016/j.ejphar.2004.01.011, PII S001429990400072X
    • J. Magyar N. Szentandrássy T. Bányász L. Fülöp A. Varró P. P. Nánási 2004 Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes Eur. J. Pharmacol. 487 29 36 15033373 10.1016/j.ejphar.2004.01. 011 1:CAS:528:DC%2BD2cXitFeiuro%3D (Pubitemid 38368979)
    • (2004) European Journal of Pharmacology , vol.487 , Issue.1-3 , pp. 29-36
    • Magyar, J.1    Szentandrassy, N.2    Banyasz, T.3    Fulop, L.4    Varro, A.5    Nanasi, P.P.6
  • 17
    • 0024341445 scopus 로고
    • A comparison of bradykinin- and capsaicin-induced myocardial and coronary effects in isolated perfused heart of guinea-pig: involvement of substance P and calcitonin gene-related peptide release
    • S. Manzini F. Perretti L. De Benedetti P. Pradelles C. A. Maggi P. Geppetti 1989 A comparison of bradykinin- and capsaicin-induced myocardial and coronary effects in isolated perfused heart of guinea-pig: involvement of substance P and calcitonin gene-related peptide release Br. J. Pharmacol. 97 303 312 2474343 1:CAS:528:DyaL1MXltV2ksL0%3D (Pubitemid 19142731)
    • (1989) British Journal of Pharmacology , vol.97 , Issue.2 , pp. 303-312
    • Manzini, S.1    Perretti, F.2    De Benedetti, L.3    Pradelles, P.4    Maggi, C.A.5    Geppetti, P.6
  • 18
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologie developments in antitumor activity and cardiotoxicity
    • DOI 10.1124/pr.56.2.6
    • G. Minotti P. Menna E. Salvatorelli G. Cairo L. Gianni 2004 Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity Pharmacol. Rev. 56 185 229 15169927 10.1124/pr.56.2.6 1:CAS:528:DC%2BD2cXltlKgtb0%3D (Pubitemid 38720829)
    • (2004) Pharmacological Reviews , vol.56 , Issue.2 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 19
    • 0026403946 scopus 로고
    • Hepatotoxicity of eugenol and related compounds in mice depleted of glutathione: Structural requirements for toxic potency
    • 1882130 1:CAS:528:DyaK3MXmtVSms7o%3D
    • T. Mizutani K. Satoh H. Nomura 1991 Hepatotoxicity of eugenol and related compounds in mice depleted of glutathione: structural requirements for toxic potency Res. Commun. Chem. Pathol. Pharmacol. 73 87 95 1882130 1:CAS:528:DyaK3MXmtVSms7o%3D
    • (1991) Res. Commun. Chem. Pathol. Pharmacol. , vol.73 , pp. 87-95
    • Mizutani, T.1    Satoh, K.2    Nomura, H.3
  • 20
    • 55449117707 scopus 로고    scopus 로고
    • Mechanisms of gastroprotective effect of eugenol in indomethacin-induced ulcer in rats
    • 18543354 10.1002/ptr.2502 1:CAS:528:DC%2BD1cXhsVaqt73E
    • M. A. Morsy A. A. Fouad 2008 Mechanisms of gastroprotective effect of eugenol in indomethacin-induced ulcer in rats Phytother. Res. 22 1361 1366 18543354 10.1002/ptr.2502 1:CAS:528:DC%2BD1cXhsVaqt73E
    • (2008) Phytother. Res. , vol.22 , pp. 1361-1366
    • Morsy, M.A.1    Fouad, A.A.2
  • 21
    • 0028874785 scopus 로고
    • The protective effects of eugenol on carbon tetrachloride induced hepatotoxicity in rats
    • 8574354 10.3109/10715769509065281 1:CAS:528:DyaK28Xis1yisw%3D%3D
    • E. Nagababu B. Sesikeran N. Lakshmaiah 1995 The protective effects of eugenol on carbon tetrachloride induced hepatotoxicity in rats Free Radic. Res. 23 617 627 8574354 10.3109/10715769509065281 1:CAS:528:DyaK28Xis1yisw%3D%3D
    • (1995) Free Radic. Res. , vol.23 , pp. 617-627
    • Nagababu, E.1    Sesikeran, B.2    Lakshmaiah, N.3
  • 22
    • 33745621282 scopus 로고    scopus 로고
    • Protective effects of eugenol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells
    • DOI 10.1016/j.fct.2006.04.011, PII S0278691506000974
    • H. C. Ou F. P. Chou T. M. Lin C. H. Yang W. H.-H. Sheu 2006 Protective effects of eugenol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells Food Chem. Toxicol. 44 1485 1495 16762475 10.1016/j.fct.2006.04.011 1:CAS:528:DC%2BD28Xmsl2isLY%3D (Pubitemid 43994281)
    • (2006) Food and Chemical Toxicology , vol.44 , Issue.9 , pp. 1485-1495
    • Ou, H.-C.1    Chou, F.-P.2    Lin, T.-M.3    Yang, C.-H.4    Sheu, W.H.-H.5
  • 23
    • 0037448784 scopus 로고    scopus 로고
    • Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction
    • DOI 10.1161/01.CIR.0000048192.52098.DD
    • P. Pacher L. Liaudet P. Bai J. G. Mabley P. M. Kaminski L. Virág A. Deb E. Szabó Z. Ungvári M. S. Wolin J. T. Groves C. Szabó 2003 Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction Circulation 107 896 904 12591762 10.1161/01.CIR.0000048192.52098.DD 1:CAS:528:DC%2BD3sXht1Cmsb0%3D (Pubitemid 36241050)
    • (2003) Circulation , vol.107 , Issue.6 , pp. 896-904
    • Pacher, P.1    Liaudet, L.2    Bai, P.3    Mabley, J.G.4    Kaminski, P.M.5    Virag, L.6    Deb, A.7    Szabo, E.8    Ungvari, Z.9    Wolin, M.S.10    Groves, J.T.11    Szabo, C.12
  • 24
    • 0034815485 scopus 로고    scopus 로고
    • Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy
    • 11589785 10.1034/j.1600-0773.2001.d01-148.x 1:CAS:528: DC%2BD3MXnsVensbs%3D
    • M. M. Sayed-Ahmed M. M. Khattab M. Z. Gad A. M. Osman 2001 Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy Pharmacol. Toxicol. 89 140 144 11589785 10.1034/j.1600-0773.2001. d01-148.x 1:CAS:528:DC%2BD3MXnsVensbs%3D
    • (2001) Pharmacol. Toxicol. , vol.89 , pp. 140-144
    • Sayed-Ahmed, M.M.1    Khattab, M.M.2    Gad, M.Z.3    Osman, A.M.4
  • 25
    • 0032563825 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy
    • DOI 10.1056/NEJM199809243391307
    • P. K. Singal N. Iliskovic 1998 Doxorubicin-induced cardiomyopathy N. Engl. J. Med. 339 900 905 9744975 10.1056/NEJM199809243391307 1:STN:280:DyaK1cvhsVektw%3D%3D (Pubitemid 28446849)
    • (1998) New England Journal of Medicine , vol.339 , Issue.13 , pp. 900-905
    • Singal, P.K.1    Iliskovic, N.2
  • 27
    • 0026068803 scopus 로고
    • Metabolism and cytotoxicity of eugenol in isolated rat hepatocytes
    • 1991333 10.1016/0009-2797(91)90069-J 1:CAS:528:DyaK3MXhsFyksbc%3D
    • D. C. Thompson D. Constantin-Teodosiu P. Moldéus 1991 Metabolism and cytotoxicity of eugenol in isolated rat hepatocytes Chem. Biol. Interact. 77 137 147 1991333 10.1016/0009-2797(91)90069-J 1:CAS:528:DyaK3MXhsFyksbc%3D
    • (1991) Chem. Biol. Interact. , vol.77 , pp. 137-147
    • Thompson, D.C.1    Constantin-Teodosiu, D.2    Moldéus, P.3
  • 28
    • 0031905294 scopus 로고    scopus 로고
    • Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays
    • DOI 10.1006/taap.1997.8348
    • D. C. Thompson R. Barhoumi R. C. Burghardt 1998 Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays Toxicol. Appl. Pharmacol. 149 55 63 9512727 10.1006/taap.1997.8348 1:CAS:528:DyaK1cXhs1alsr0%3D (Pubitemid 28105572)
    • (1998) Toxicology and Applied Pharmacology , vol.149 , Issue.1 , pp. 55-63
    • Thompson, D.C.1    Barhoumi, R.2    Burghardt, R.C.3
  • 29
    • 13844266162 scopus 로고    scopus 로고
    • Eugenol as an in vivo radioprotective agent
    • DOI 10.1269/jrr.45.435
    • A. B. Tiku S. K. Abraham R. K. Kale 2004 Eugenol as an in vivo radioprotective agent J. Radiat. Res. 45 435 440 15613789 10.1269/jrr.45.435 1:CAS:528:DC%2BD2MXisVOqsb8%3D (Pubitemid 40254072)
    • (2004) Journal of Radiation Research , vol.45 , Issue.3 , pp. 435-440
    • Tiku, A.B.1    Abraham, S.K.2    Kale, R.K.3
  • 30
    • 20544451368 scopus 로고    scopus 로고
    • The protective effects of rutaecarpine on gastric mucosa injury in rats
    • DOI 10.1055/s-2005-864135
    • L. Wang C. P. Hu P. Y. Deng S. S. Shen H. Q. Zhu J. S. Ding G. S. Tan Y. J. Li 2005 The protective effects of rutaecarpine on gastric mucosa injury in rats Planta Med. 71 416 419 15931578 10.1055/s-2005-864135 1:CAS:528: DC%2BD2MXlsFemtbY%3D (Pubitemid 40839773)
    • (2005) Planta Medica , vol.71 , Issue.5 , pp. 416-419
    • Wang, L.1    Hu, C.-P.2    Deng, P.-Y.3    Shen, S.-S.4    Zhu, H.-Q.5    Ding, J.-S.6    Tan, G.-S.7    Li, Y.-J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.