Chemical composition of the ethanolic propolis extracts and its effect on HeLa cells

Journal of Ethnopharmacology

Volumn 135, Issue 3, 2011, Pages 772-778

  Barbarić, Monika ^a   Mišković, Katarina ^b   Bojić, Mirza ^a   Lončar, Mirela Baus ^b,c   Smolčić Bubalo, Asja ^d   Debeljak, Željko ^a   Medić Šarić, Marica ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b Department of Medicinal Biology   (Croatia)

^c RUDER BO KOVI INSTITUTE   (Croatia)

^d Phyto Pharma   (Croatia)

Author keywords

Cytotoxic evaluation; Flavonoids; HeLa; HPLC; Phenolic acids; Propolis

Indexed keywords

APIGENIN; CAFFEIC ACID; CHRYSIN; FERULIC ACID; GALANGIN; KAEMPFEROL; PARA COUMARIC ACID; PINOCEMBRINE; PROPOLIS; QUERCETIN; TECTOCHRYSIN;

ARTICLE; CELL GROWTH; CHEMICAL COMPOSITION; CYTOTOXICITY; DRUG EFFECT; DRUG STRUCTURE; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; UTERINE CERVIX CARCINOMA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APITHERAPY; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EUROPE, EASTERN; FEMALE; FLAVONOIDS; HELA CELLS; HUMANS; HYDROXYBENZOIC ACIDS; MOLECULAR STRUCTURE; PHYTOTHERAPY; PROPOLIS;

EID: 79957501869     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.015     Document Type: Article

References (42)

1. F.K. Abd El-Hadi, and A.G. Hegazi Egyptian propolis: 2. Chemical composition, antiviral and antimicrobial activities of East Nile Delta propolis Zeitschrift für Naturforschung 57c 2002 386 394 (Pubitemid 34489940)
2. N.S. Al-Waili Clinical and mycological benefits of topical application of honey, olive oil and beeswax in diaper dermatitis Clinical Microbiology and Infection 11 2005 160 163 (Pubitemid 40253825)
3. M. Amoros, E. Lurton, J. Boustie, L. Girre, F. Sauvager, and M. Cormier Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate Journal of Natural Products 57 1994 644 647 (Pubitemid 24196760)
4. M. Amoros, F. Sauvager, L. Girre, and M. Cormier In vitro antiviral activity of propolis Apidologie 23 1992 231 240
5. J. Ban, Š. Popović, and D. Maysinger Cytostatic effect of propolis in vitro Acta Pharmaceutica Jugoslavica 33 1983 245 255
6. V.S. Bankova, S.L. De Castro, and M.C. Marucci Propolis: recent advances in chemistry and plant origin Apidologie 31 2000 3 15 (Pubitemid 30106313)
7. V.S. Bankova, S.S. Popov, and N.L. Marekov High-performance-liquid chromatography analysis of flavonoids from propolis Journal of Chromatography 242 1982 135 143
8. F. Borrelli, P. Maffia, L. Pinto, A. Ianaro, A. Russo, F. Capasso, and A. Ialenti Phytochemical compounds involved in the anti-inflammatory effect of propolis extract Fitoterapia 73 2002 S53 S63
9. L. Boyanova, G. Gergova, R. Nikolov, S. Derejian, E. Lazarova, N. Katsarov, I. Mitov, and Z. Krastev Activity of Bulgarian propolis against 94 Helicobacter pylori strains in vitro by agar-well diffusion, agar dilution and disc diffusion methods Journal of Medical Microbiology 54 2005 481 483 (Pubitemid 40605167)
10. M.L. Bruschi, S.L. Franco, and M.P.D. Gremiao Application of an HPLC method for analysis of propolis extract Journal of Liquid Chromatography & Related Technologies 26 2003 2399 2409 (Pubitemid 37022181)
11. G.A. Burdock Review of the biological properties and toxicity of bee propolis Food and Chemical Toxicology 36 1998 347 363 (Pubitemid 28255348)
12. S. Castaldo, and F. Capasso Propolis, an old remedy used in modern medicine Fitoterapia 73 2002 S1 S6
13. C. Chiao, A.M. Carothers, D. Grunberger, G. Solomon, A.G. Preston, and C.J. Barrett Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells Cancer Research 55 1995 3576 3583
14. J. Cvek, M. Medić-Šarić, I. Jasprica, S. Zubčić, D. Vitali, A. Mornar, I. Vedrina-Dragojević, and S. Tomić Optimisation of an extraction procedure and chemical characterisation of Croatian propolis tinctures Phytochemical Analysis 18 2007 451 459 (Pubitemid 47422802)
15. M. Debiaggi, F. Tateo, L. Pagani, M. Luini, and E. Romero Effects of propolis flavonoids on virus infectivity and replication Microbiologica 13 1990 207 213 (Pubitemid 20336867)
16. O.-A.Y. El-khawaga, T.A. Salem, and M.F. Elshal Protective role of Egyptian propolis against tumor in mice Clinica Chimica Acta 338 2003 11 16 (Pubitemid 37456683)
17. J.D. Fontana, M. Passos, M.H.R. dos Santos, C.K. Fontana, B.H. Oliveira, L. Schause, R. Pontarolo, A. Barbirato, M.A. Ruggiero, and F.M. Lancas Profiling propolis flavonoids by means of micellar electrokinetic capillary chromatography, capillary gas chromatography and bactericidal action Chromatographia 52 2000 147 151 (Pubitemid 30643970)
18. J. Galvao, J.A. Abreu, T. Cruz, G.A.S. Machado, P. Niraldo, A. Daugasch, C.S. Moraes, P. Fort, and Y.K. Park Biological therapy using propolis as nutritional supplement in cancer treatment International Journal of Cancer Research 3 2007 43 53 (Pubitemid 46805395)
19. E. Ghisalberti Propolis: a review Bee World 60 1979 59 84
20. R. Gonzales, I. Corcho, and D. Remirez Hepatoprotective effects of propolis extract on carbon tetrachloride-induced liver injury in rats Phytotherapy Research 9 1995 14 17
21. J. Ito, F.-R. Chang, H.-K. Wang, Y.K. Park, M. Ikegaki, N. Kilgore, and K.-H. Lee Anti-AIDS agents 48: anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis Journal of Natural Products 64 2001 1278 1281 (Pubitemid 33029206)
22. M. Kartal, S. Yildiz, S. Kaya, S. Kurucu, and G. Topcu Antimicrobial activity of propolis samples from two different regions of Anatolia Journal of Ethnopharmacology 56 2003 69 73 (Pubitemid 36398661)
23. H. Koo, B.P.F.A. Gomes, P.L. Rosalen, G.M.B. Ambrosano, Y.K. Park, and J.A. Cury In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens Archives of Oral Biology 45 2000 141 148 (Pubitemid 30097337)
24. A. Kujumgiev, I. Svetkova, Y. Serkedjieva, V. Bankova, R. Christov, and S. Popov Antibacterial, antifungal and antiviral activity of propolis of different geographic origin Journal of Ethnopharmacology 64 1999 235 240 (Pubitemid 29170208)
25. M.C. Marcucci Propolis: chemical composition, biological properties and therapeutical activity Apidologie 26 1995 83 99
26. K.R. Markham, K.A. Mitchell, A.L. Wilkins, J.A. Daldy, and Y. Lu HPLC and GC-MS identification of the major organic constituents in New Zealand propolis Phytochemistry 42 1996 205 211 (Pubitemid 126686184)
27. M. Medić-Šarić, V. Rastija, and M. Bojić Recent advances in the application of high-performance liquid chromatography in analysis of polyphenols in wine and propolis Journal of AOAC International 94 2011 32 42
28. G. Mickisch, S. Fajta, H. Bier, R. Tschada, and P. Alken Cross-resistance patterns related to glutathione metabolism in primary human renal cell carcinoma Urological Research 19 1991 99 103
29. M.F. Najafi, F. Vahedy, M. Seyyedin, H.R. Jomehzadeh, and K. Bozary Effect of the water extracts of propolis on stimulation and inhibition of different cells Cytotechnology 54 2007 49 56 (Pubitemid 46944863)
30. Y. Nakajima, M. Shimazawa, S. Mishima, and H. Hara Water extract of propolis and its main constituents, caffeoylquinic acid derivatives, exert neuroprotective effects via antioxidant actions Life Sciences 80 2007 370 377 (Pubitemid 44958715)
31. N. Oršolić, and I. Bašić Immunomodulation by water-soluble derivative of propolis (WSDP) a factor of antitumor reactivity Journal of Ethnopharmacology 84 2003 265 273 (Pubitemid 36324266)
32. N. Oršolić, and I. Bašić Water-soluble derivative of propolis and its polyphenolic compounds enhance tumoricidal activity of macrophages Journal of Ethnopharmacology 102 2005 37 45 (Pubitemid 41375936)
33. N. Oršolić, A. Horvat Knežević, L. Šver, S. Terzić, and I. Bašić Immunomodulatory and antimetastatic action of propolis and related polyphenolic compounds Journal of Ethnopharmacology 94 2004 307 315 (Pubitemid 39127467)
34. M.H. Pan, and C.T. Ho Chemopreventive effects of natural dietary compounds on cancer development Chemical Society Reviews 37 2008 2558 2574
35. M. Popova, S. Silici, O. Kaftanoglu, and V. Bankova Antibacterial activity of Turkish propolis and its qualitative and quantitative chemical composition Phytomedicine 12 2005 221 228 (Pubitemid 40348624)
36. C.V. Rao, D. Desai, A. Rivenson, B. Simi, S. Amin, and S.B. Reddy Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate Cancer Research 55 1995 2310 2315
37. A. Russo, R. Longo, and A. Vanella Antioxidant activity of propolis: role of caffeic acid and phenethyl ester and galangin Fitoterapia 73 2002 S21 29
38. S. Scheller, S. Dworniczak, K. Waldemar-Klimmek, M. Rajca, A. Tomczyk, and J. Shani Synergism between ethanolic extract of propolis (EEP) and anti-tuberculosis drugs on growth of mycobacteria Zeitschrift für Naturforschung 54c 1999 549 553 (Pubitemid 29414018)
39. S. Scheller, W. Krol, J. Swiacik, S. Owezarek, J. Gabrys, and J. Shani Antitumoral property of ethanolic extract of propolis in mice bearing Ehrlich carcinoma, as compared to bleomycin Zeitschrift für Naturforschung Section C - Journal of Biosciences 44 1989 1049 1052
40. P. Schnitzler, A. Neuner, S. Nolkemper, C. Zundel, H. Nowack, K.H. Sensch, and J. Reichling Antiviral activity and mode of action of propolis extracts and selected compounds Phytotherapy Research 1 2010 20 28
41. N.B. Takaisi-Kikuni, and H. Schilcher Electron microscopic and microcalorimetric investigations of the possible mechanism of the antibacterial action of a defined propolis provenance Planta Medica 60 1994 222 227 (Pubitemid 24207713)
42. A.R. Waladkhani, and M.R. Clemens Effect of dietary phytochemicals on cancer development International Journal of Molecular Medicine 1 1998 747 753