Mitochondrial toxin betulinic acid induces in vitro eryptosis in human red blood cells through membrane permeabilization

Archives of Toxicology

Volumn 88, Issue 3, 2014, Pages 755-768

  Gao, Minghui ^a   Lau, P M ^a   Kong, S K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Ca2+ i; Betulinic acid; Eryptosis; Erythrocytes; Erythroptosis; Membrane permeabilization

Indexed keywords

BETULIC ACID; CALCEIN; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; PHOSPHATIDYLSERINE; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; CALCIUM; IMIDAZOLE DERIVATIVE; TRITERPENE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM DEPLETION; CANCER CELL CULTURE; CELL DEATH; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL PERMEABILIZATION; CELL TRANSFORMATION; CONTROLLED STUDY; ECHINOCYTE; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LETHAL DOSE; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; APOPTOSIS; CELL CULTURE; DRUG EFFECTS; METABOLISM; MITOCHONDRION;

BETULA PENDULA; BETULA PUBESCENS;

APOPTOSIS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; ERYTHROCYTES; HUMANS; IMIDAZOLES; MITOCHONDRIA; TRITERPENES;

EID: 84896695556     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1162-x     Document Type: Article

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