Polyphyllin D induces apoptosis in human erythrocytes through Ca 2+ rise and membrane permeabilization

Archives of Toxicology

Volumn 86, Issue 5, 2012, Pages 741-752

  Gao, Minghui ^a   Cheung, K L ^a   Lau, Irene P ^a   Yu, W S ^a   Fung, K P ^a   Yu, Biao ^b   Loo, J F ^a   Kong, S K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

Ca 2+; Caspase 3; Eryptosis; Erythrocytes; Erythroptosis; Polyphyllin D

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM ION; CASPASE 3; POLYPHYLLIN D; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL SIZE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DRUG CYTOTOXICITY; DRUG STRUCTURE; ERYPTOSIS; ERYTHROCYTE; ERYTHROCYTE GHOST; FLOW CYTOMETRY; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; PRIORITY JOURNAL;

APOPTOSIS; CALCIUM; CASPASE 3; CELL MEMBRANE PERMEABILITY; CELL SIZE; CELLS, CULTURED; CYTOSOL; DIOSGENIN; ERYTHROCYTES; HUMANS; MITOCHONDRIAL MEMBRANES;

PARIS POLYPHYLLA;

EID: 84862871418     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0808-4     Document Type: Article

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