메뉴 건너뛰기




Volumn 81, Issue 1, 2014, Pages 30-37

Consumption of transgenic milk containing the antimicrobials lactoferrin and lysozyme separately and in conjunction by 6-week-old pigs improves intestinal and systemic health

Author keywords

Hemaetology; Lactoferrin; Lysozyme; Milk; Pigs; Transgenic

Indexed keywords

ANIMALIA; BOS; BOVIDAE; CAPRA HIRCUS; SUIDAE;

EID: 84896548975     PISSN: 00220299     EISSN: 14697629     Source Type: Journal    
DOI: 10.1017/S0022029913000575     Document Type: Article
Times cited : (19)

References (54)
  • 2
    • 42449129106 scopus 로고    scopus 로고
    • Lysozyme transgenic goats' milk influences gastrointestinal morphology in young pigs
    • Brundige DR, Maga EA, Klasing KC & Murray JD 2008 Lysozyme transgenic goats' milk influences gastrointestinal morphology in young pigs. Journal of Nutrition 138 921-926
    • (2008) Journal of Nutrition , vol.138 , pp. 921-926
    • Brundige, D.R.1    Maga, E.A.2    Klasing, K.C.3    Murray, J.D.4
  • 3
    • 77954534431 scopus 로고    scopus 로고
    • Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs
    • Brundige DR, Maga EA, Klasing KC & Murray JD 2010 Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs. Transgenic Research 19 563-574
    • (2010) Transgenic Research , vol.19 , pp. 563-574
    • Brundige, D.R.1    Maga, E.A.2    Klasing, K.C.3    Murray, J.D.4
  • 4
    • 55949117486 scopus 로고    scopus 로고
    • 28-day repeated dose oral toxicity of recombinant human holo-lactoferrin in rats
    • Cerven D, DeGeorge G & Bethell D 2008 28-day repeated dose oral toxicity of recombinant human holo-lactoferrin in rats. Regulatory Toxicology and Pharmacology 52 174-179
    • (2008) Regulatory Toxicology and Pharmacology , vol.52 , pp. 174-179
    • Cerven, D.1    Degeorge, G.2    Bethell, D.3
  • 5
    • 77958005310 scopus 로고    scopus 로고
    • Effects of diets containing different concentrations of propolis on hematological and immunological variables in laying hens
    • Cetin E, Silici S, Cetin N & Güçlü BK 2010 Effects of diets containing different concentrations of propolis on hematological and immunological variables in laying hens. Poultry Science 89 1703-1708
    • (2010) Poultry Science , vol.89 , pp. 1703-1708
    • Cetin, E.1    Silici, S.2    Cetin, N.3    Güçlü, B.K.4
  • 6
    • 80855133479 scopus 로고    scopus 로고
    • Lysozyme transgenic goats' milk positively impacts intestinal cytokine expression and morphology
    • Cooper CA, Brundige DR, Reh WA, Maga EA & Murray JD 2011 Lysozyme transgenic goats' milk positively impacts intestinal cytokine expression and morphology. Transgenic Research 20 1235-1243
    • (2011) Transgenic Research , vol.20 , pp. 1235-1243
    • Cooper, C.A.1    Brundige, D.R.2    Reh, W.A.3    Maga, E.A.4    Murray, J.D.5
  • 7
    • 84877740988 scopus 로고    scopus 로고
    • Consumption of transgenic cows' milk containing human lactoferrin results in beneficial changes in the gastrointestinal tract and systemic health of young pigs
    • Cooper CA, Nelson KM, Maga EA & Murray JD 2013 Consumption of transgenic cows' milk containing human lactoferrin results in beneficial changes in the gastrointestinal tract and systemic health of young pigs. Transgenic Research 22 571-578
    • (2013) Transgenic Research , vol.22 , pp. 571-578
    • Cooper, C.A.1    Nelson, K.M.2    Maga, E.A.3    Murray, J.D.4
  • 8
    • 84868526205 scopus 로고    scopus 로고
    • Hepcidin and the iron-infection axis
    • Drakesmith H & Prentice AM 2012 Hepcidin and the iron-infection axis. Science 338 768-772
    • (2012) Science , vol.338 , pp. 768-772
    • Drakesmith, H.1    Prentice, A.M.2
  • 9
    • 0026095436 scopus 로고
    • Killing of Gram-negative bacteria by lactoferrin and lysozyme
    • Ellison RTJ & Giehl TJ 1991 Killing of Gram-negative bacteria by lactoferrin and lysozyme. Journal of Clinical Investigation 88 1080-1091
    • (1991) Journal of Clinical Investigation , vol.88 , pp. 1080-1091
    • Ellison, R.T.J.1    Giehl, T.J.2
  • 11
    • 0344875071 scopus 로고    scopus 로고
    • Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress
    • Fonseca AM, Pereira CF, Porto G & Arosa FA 2003 Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress. Free Radical Biology and Medicine 35 1404-1416
    • (2003) Free Radical Biology and Medicine , vol.35 , pp. 1404-1416
    • Fonseca, A.M.1    Pereira, C.F.2    Porto, G.3    Arosa, F.A.4
  • 12
    • 0036233799 scopus 로고    scopus 로고
    • Role of lipoteichoic acid in infection and inflammation
    • Ginsburg I 2002 Role of lipoteichoic acid in infection and inflammation. Lancet Infectious Disease 2 171-179
    • (2002) Lancet Infectious Disease , vol.2 , pp. 171-179
    • Ginsburg, I.1
  • 14
    • 77956271563 scopus 로고    scopus 로고
    • Effect of probiotics enriched diet on paralichthys olivaceus infected with lymphocystis disease virus (lcdv
    • Harikrishnan R, Balasundaram C & Heo MS 2010 Effect of probiotics enriched diet on Paralichthys olivaceus infected with lymphocystis disease virus (LCDV). Fish and Shellfish Immunology 29 868-874
    • (2010) Fish and Shellfish Immunology , vol.29 , pp. 868-874
    • Harikrishnan, R.1    Balasundaram, C.2    Heo, M.S.3
  • 15
    • 84860682715 scopus 로고    scopus 로고
    • Pomegranate enriched diet enhances the hematology, innate immune response, and disease resistance in olive flounder against philasterides dicentrarchi
    • Harikrishnan R, Kim JS, Kim MC, Balasundaram C & Heo MS 2012 Pomegranate enriched diet enhances the hematology, innate immune response, and disease resistance in olive flounder against Philasterides dicentrarchi. Veterinary Parasitology 187 147-156
    • (2012) Veterinary Parasitology , vol.187 , pp. 147-156
    • Harikrishnan, R.1    Kim, J.S.2    Kim, M.C.3    Balasundaram, C.4    Heo, M.S.5
  • 17
    • 84861416827 scopus 로고    scopus 로고
    • Transgenic milk containing recombinant human lactoferrin modulates the intestinal flora in piglets
    • Hu W, Zhao J, Wang J, Yu T, Wang J & Li N 2012 Transgenic milk containing recombinant human lactoferrin modulates the intestinal flora in piglets. Biochemistry and Cell Biology 90 485-496
    • (2012) Biochemistry and Cell Biology , vol.90 , pp. 485-496
    • Hu, W.1    Zhao, J.2    Wang, J.3    Yu, T.4    Wang, J.5    Li, N.6
  • 18
    • 0036277078 scopus 로고    scopus 로고
    • Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks
    • Humphrey BD, Huang N & Klasing KC 2002 Rice expressing lactoferrin and lysozyme has antibiotic-like properties when fed to chicks. Journal of Nutrition 132 1214-1218
    • (2002) Journal of Nutrition , vol.132 , pp. 1214-1218
    • Humphrey, B.D.1    Huang, N.2    Klasing, K.C.3
  • 19
    • 77449106558 scopus 로고    scopus 로고
    • Haematopoietic properties of ethanolic extract of Ageratum conyzoides (goat weed) in albino rats
    • Ita SO, Etim OE, Ben EE & Ekpo OF 2007 Haematopoietic properties of ethanolic extract of Ageratum conyzoides (goat weed) in albino rats. Niger Journal of Physiological Science 22 83-87
    • (2007) Niger Journal of Physiological Science , vol.22 , pp. 83-87
    • Ita, S.O.1    Etim, O.E.2    Ben, E.E.3    Ekpo, O.F.4
  • 20
    • 0019869031 scopus 로고
    • Iron uptake and ferritin synthesis by peripheral blood leucocytes in patients with primary idiopathic haemochromatosis
    • Jacobs A & Summers MR 1981 Iron uptake and ferritin synthesis by peripheral blood leucocytes in patients with primary idiopathic haemochromatosis. British Journal of Haematology 49 649-652
    • (1981) British Journal of Haematology , vol.49 , pp. 649-652
    • Jacobs, A.1    Summers, M.R.2
  • 22
    • 84862813626 scopus 로고    scopus 로고
    • Effects of graded levels of dietary methionine hydroxy analogue on immune response and antioxidant status of immune organs in juvenile jian carp (cyprinus carpio var
    • Kuang SY, XiaoWW, Feng L, Liu Y, Jiang J, Jiang WD, Hu K, Li SH, Tang L & Zhou XQ 2012 Effects of graded levels of dietary methionine hydroxy analogue on immune response and antioxidant status of immune organs in juvenile Jian carp (Cyprinus carpio var. Jian). Fish and Shellfish Immunology 32 629-636
    • (2012) Jian). Fish and Shellfish Immunology , vol.32 , pp. 629-636
    • Kuang, S.Y.1    Xiaow, W.2    Feng, L.3    Liu, Y.4    Jiang, J.5    Jiang, W.D.6    Hu, K.7    Li, S.H.8    Tang, L.9    Zhou, X.Q.10
  • 24
    • 64549148418 scopus 로고    scopus 로고
    • Hen egg lysozyme attenuates inflammation and modulates local gene expression in a porcine model of dextran sodium sulfate (dss)-induced colitus
    • Lee M, Kovacs-Nolan J, Yang C, Archibold T, Fan MZ & Mine Y 2009 Hen egg lysozyme attenuates inflammation and modulates local gene expression in a porcine model of dextran sodium sulfate (DSS)-induced colitus. Journal of Agricultural Food Chemistry 57 2233-2240
    • (2009) Journal of Agricultural Food Chemistry , vol.57 , pp. 2233-2240
    • Lee, M.1    Kovacs-Nolan, J.2    Yang, C.3    Archibold, T.4    Fan, M.Z.5    Mine, Y.6
  • 25
    • 0032846808 scopus 로고    scopus 로고
    • Elucidation of the antistaphylococcal action of lactoferrin and lysozyme
    • Leitch EC & WilcoxMD1999 Elucidation of the antistaphylococcal action of lactoferrin and lysozyme. Journal of Medical Microbiology 48 867-871
    • (1999) Journal of Medical Microbiology , vol.48 , pp. 867-871
    • Leitch, E.C.1    Wilcox, M.D.2
  • 27
    • 84861405764 scopus 로고    scopus 로고
    • Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life
    • Liao Y, Jiang R & Lonnerdal B 2012 Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life. Biochemistry and Cell Biology 90 476-484
    • (2012) Biochemistry and Cell Biology , vol.90 , pp. 476-484
    • Liao, Y.1    Jiang, R.2    Lonnerdal, B.3
  • 28
    • 77449093071 scopus 로고    scopus 로고
    • Exogenous lysozyme influences clostridium perfringens colonization and intestinal barrier function in broiler chickens
    • Liu D, Guo Y, Wang Z & Yuan J 2010 Exogenous lysozyme influences Clostridium perfringens colonization and intestinal barrier function in broiler chickens. Avian Pathology 39 17-24
    • (2010) Avian Pathology , vol.39 , pp. 17-24
    • Liu, D.1    Guo, Y.2    Wang, Z.3    Yuan, J.4
  • 31
    • 33846244198 scopus 로고    scopus 로고
    • Human lysozyme expressed in the mammary gland of transgenic dairy goats can inhibit the growth of bacteria that cause mastitis and the cold-spoilage of milk
    • Maga EA, Cullor JS, Smith W, Anderson GB & Murray JD 2006b Human lysozyme expressed in the mammary gland of transgenic dairy goats can inhibit the growth of bacteria that cause mastitis and the cold-spoilage of milk. Foodborne Pathology and Disease 3 384-392
    • (2006) Foodborne Pathology and Disease , vol.3 , pp. 384-392
    • Maga, E.A.1    Cullor, J.S.2    Smith, W.3    Anderson, G.B.4    Murray, J.D.5
  • 32
    • 33747063054 scopus 로고    scopus 로고
    • Consumption of milk from transgenic goats expressing human lysozyme in the mammary gland results in the modulation of intestinal microflora
    • Maga EA, Walker RL, Anderson GB & Murray JD 2006c Consumption of milk from transgenic goats expressing human lysozyme in the mammary gland results in the modulation of intestinal microflora. Transgenic Research 15 515-519
    • (2006) Transgenic Research , vol.15 , pp. 515-519
    • Maga, E.A.1    Walker, R.L.2    Anderson, G.B.3    Murray, J.D.4
  • 34
    • 84859181233 scopus 로고    scopus 로고
    • Breeder age affects small intestine development of broiler chicks with immediate or delayed access to feed
    • Mahmoud KZ & Edens FW 2012 Breeder age affects small intestine development of broiler chicks with immediate or delayed access to feed. British Poultry Science 53 32-41
    • (2012) British Poultry Science , vol.53 , pp. 32-41
    • Mahmoud, K.Z.1    Edens, F.W.2
  • 37
    • 0036265580 scopus 로고    scopus 로고
    • Intestinal microflora of human infants and current trends for its nutritional modulation
    • Mountzouris KC, McCartney AL & Gibson GR 2002 Intestinal microflora of human infants and current trends for its nutritional modulation. British Journal of Nutrition 87 405-420
    • (2002) British Journal of Nutrition , vol.87 , pp. 405-420
    • Mountzouris, K.C.1    McCartney, A.L.2    Gibson, G.R.3
  • 38
    • 33846953590 scopus 로고    scopus 로고
    • Protection of the neonate by the innate immune system of developing gut and of human milk
    • Newburg DS & Walker WA 2007 Protection of the neonate by the innate immune system of developing gut and of human milk. Pediatric Research 61 2-8
    • (2007) Pediatric Research , vol.61 , pp. 2-8
    • Newburg, D.S.1    Walker, W.A.2
  • 40
    • 0024519425 scopus 로고
    • Lipopolysaccharide interaction with lysozyme Binding of lipopolysaccharide to lysozyme and inhibition of lysozyme enzymatic activity
    • Ohno N & Morrison DC 1989a Lipopolysaccharide interaction with lysozyme. Binding of lipopolysaccharide to lysozyme and inhibition of lysozyme enzymatic activity. Journal of Biological Chemistry 264 4434-4441
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 4434-4441
    • Ohno, N.1    Morrison, D.C.2
  • 41
    • 0024847905 scopus 로고
    • Lipopolysaccharide interactions with lysozyme differentially affect lipopolysaccharide immunostimulatory activity
    • Ohno N & Morrison DC 1989b Lipopolysaccharide interactions with lysozyme differentially affect lipopolysaccharide immunostimulatory activity. European Journal of Biochemistry 186 629-636
    • (1989) European Journal of Biochemistry , vol.186 , pp. 629-636
    • Ohno, N.1    Morrison, D.C.2
  • 42
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • Pfaffl MW, Horgan GW & Dempfle L 2002 Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Research 30 36
    • (2002) Nucleic Acids Research , vol.30 , pp. 36
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 43
    • 34848886661 scopus 로고    scopus 로고
    • Use of human lysozyme transgenic goat milk in cheese making: Effects on lactic acid bacteria performance
    • Scharfen EC, Mills DA & Maga EA 2007 Use of human lysozyme transgenic goat milk in cheese making: effects on lactic acid bacteria performance. Journal of Dairy Science 90 4084-4091
    • (2007) Journal of Dairy Science , vol.90 , pp. 4084-4091
    • Scharfen, E.C.1    Mills, D.A.2    Maga, E.A.3
  • 44
    • 0028324925 scopus 로고
    • Binding of lysozyme to lipopolysaccharide suppresses tumor necrosis factor production in vivo
    • Takada K, Ohno N & Yadomae T 1994a Binding of lysozyme to lipopolysaccharide suppresses tumor necrosis factor production in vivo. Infection and Immunity 62 1171-1175
    • (1994) Infection and Immunity , vol.62 , pp. 1171-1175
    • Takada, K.1    Ohno, N.2    Yadomae, T.3
  • 46
    • 23744501922 scopus 로고    scopus 로고
    • The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin
    • Thomassen EA, van Veen HA, van Berkel PH, Nuijens JH & Abrahams JP 2005 The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin. Transgenic Research 14 397-405
    • (2005) Transgenic Research , vol.14 , pp. 397-405
    • Thomassen, E.A.1    Van Veen, H.A.2    Van Berkel, P.H.3    Nuijens, J.H.4    Abrahams, J.P.5
  • 49
    • 69849106960 scopus 로고    scopus 로고
    • Coli O157:H7 and Staphylococcus aureus 1056 MRSA
    • coli O157:H7 and Staphylococcus aureus 1056 MRSA. Biotechnology Letters 31 1265-1267
    • Biotechnology Letters , vol.31 , pp. 1265-1267
  • 51
    • 84866382685 scopus 로고    scopus 로고
    • Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent
    • Wu X, Yung LM, Cheng WH, Yu PB, Babitt JL, Lin HY & Xia Y 2012 Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent. PLoS ONE 7 e44622
    • (2012) PLoS ONE , vol.7
    • Wu, X.1    Yung, L.M.2    Cheng, W.H.3    Yu, P.B.4    Babitt, J.L.5    Lin, H.Y.6    Xia, Y.7
  • 53
    • 61849184878 scopus 로고    scopus 로고
    • Lactoferrin as a natural regimen for selective decontamination of the digestive tract: Recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonates from pathogenic challenge in the gastrointestinal tract
    • Yen CC, Lin CY, Chong KY, Tsai TC, Shen CJ, Lin MF, Su CY, Chen HL & Chen CM 2009 Lactoferrin as a natural regimen for selective decontamination of the digestive tract: recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonates from pathogenic challenge in the gastrointestinal tract. Journal of Infectious Disease 199 590-598
    • (2009) Journal of Infectious Disease , vol.199 , pp. 590-598
    • Yen, C.C.1    Lin, C.Y.2    Chong, K.Y.3    Tsai, T.C.4    Shen, C.J.5    Lin, M.F.6    Su, C.Y.7    Chen, H.L.8    Chen, C.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.